Effect of Remifentanil on Postoperative Cognition Function in Patients Undergoing Major Abdominal Surgery
NCT01627873, Phase 4, Completed, Catholic University of the Sacred Heart
Trial 10
As registered on ClinicalTrials.gov, in the graph's capture of the registry.
| Field | Value | Source |
|---|---|---|
| Title | Effect of Remifentanil on Postoperative Cognition Function in Patients Undergoing Major Abdominal Surgery | ClinicalTrials.gov |
| NCT number | NCT01627873 | ClinicalTrials.gov |
| Status | Completed | ClinicalTrials.gov |
| Phases | Phase 4 | ClinicalTrials.gov |
| Enrollment | 622 participants, actual | ClinicalTrials.gov |
| Lead sponsor | Catholic University of the Sacred Heart | ClinicalTrials.gov |
| Conditions | Patients Undergoing Major Abdominal Surgery, Postoperative Confusion | ClinicalTrials.gov |
| Interventions | Remifentanil, Fentanyl | ClinicalTrials.gov |
| First posted | 2012-06-26 | ClinicalTrials.gov |
| Last updated | 2012-06-26 | ClinicalTrials.gov |
Registered outcomes 3
Each outcome the trial registered, primary first, in ClinicalTrials.gov's words.
| List | Outcome | Time frame | Description | Source |
|---|---|---|---|---|
| Primary | Rey verbal memory test of words before and after major abdominal surgery | participants will be followed the day before and after surgery and for the duration of hospital stay, an expected average of 5 days | In test of Rey to the subject is presented for 5 times the same list of 15 bisyllabic words or trisillabic common use of which he must recall as many as possible within 1 minute; after about 15 minutes the patient, meanwhile distracted by the test , must again try to remember the greatest number possible without a further reading. The maximum possible score of the first phase of the test is an expression of the ability of short term memory of the subject, the result of the test is repeated at a distance of 15 minutes is indicative of its storage capacity, to intermediate term. | ClinicalTrials.gov |
| Primary | Stroop Test before and after surgery | participants will be followed the day before and after surgery and for the duration of hospital stay, an expected average of 5 days | In the Stroop Test patient is instructed to read a random sequence of adjectives "green", "red", "blue" written in black font, then he refers the colour of a succession of circumferences filled of the three colors above in random order; finally, another random succession of three words "green", "red", "blue" written in three characters of the same colors, but not associated with corresponding adjective. Number of errors that the subject does in reading is an indication of its ability to attention | ClinicalTrials.gov |
| Secondary | Quantitative determination of serum pro and anti inflammatory cytokines before and after surgery | participants will be followed the day before and after surgery and for the duration of hospital stay, an expected average of 5 days | Blood samples will be made for the quantitative determination of serum cytokines IL-1β, IL-6, IL-8, TNF-α, IL-10 and IL-12. Determinations will be given by Multiplex Elisa method. | ClinicalTrials.gov |
Outcomes 0
Each outcome the trial posted results for, in ClinicalTrials.gov's words.
| Type | Outcome | Time frame | Population | Units | Measured as | Source |
|---|
Results by group 0
Each measurement the trial posted, group by group, in the words and numbers it posted.
| Outcome | Group | Category | Value | Spread | Units | Source |
|---|
Participant flow 0
How many started, completed or left each group, period by period.
| Period | Milestone | Group | Participants | Units counted | Source |
|---|
Adverse events 0
Each adverse event the trial posted, group by group: the participants affected out of those at risk.
| Type | Event | Organ system | Group | Affected | At risk | Events | Source |
|---|
Adverse event totals 0
The totals the trial posted for each group.
| Total | Group | Affected | At risk | Source |
|---|
Papers 13
The papers the trial lists on ClinicalTrials.gov.
| PMID | Listed as | Source |
|---|---|---|
| 7762856 | BACKGROUND | PubMed |
| 9248516 | BACKGROUND | PubMed |
| 9525362 | BACKGROUND | PubMed |
| 9861139 | BACKGROUND | PubMed |
| 10603995 | BACKGROUND | PubMed |
| 10800812 | BACKGROUND | PubMed |
| 10935000 | BACKGROUND | PubMed |
| 12078822 | BACKGROUND | PubMed |
| 12473019 | BACKGROUND | PubMed |
| 15684252 | BACKGROUND | PubMed |
| 16508385 | BACKGROUND | PubMed |
| 17325501 | BACKGROUND | PubMed |
| 18005471 | BACKGROUND | PubMed |
Trial comparisons 0
Comparisons of the trial's two groups, calculated by ConductScience from the counts it posted.
| Comparison | Source |
|---|
Tests 1
The ConductCognition tests this trial's registered outcomes name, as ScienceGraph matched them in trial-tests-2026-11-12-0.2.1.
| Test | Named as | Source |
|---|---|---|
| Stroop Color-Word Test | Primary outcome | ConductCognition |
Source 4
| Field | Value | Source |
|---|---|---|
| Release | trials-2026-11-12-0.3.0 | ClinicalTrials.gov |
| Release manifest SHA-256 | 4a570df2e7274cee2d4fa2959402fab41880e2cd412e4b590390035fbea69391 | ClinicalTrials.gov |
| Registry capture | 2026-11-12 | ClinicalTrials.gov |
| Results copy, AACT | 2026-03-23 | ClinicalTrials.gov |
Release trials-2026-11-12-0.3.0
ClinicalTrials.gov's posted results, through CTTI's AACT: ClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299 ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.
ClinicalTrials.gov: none stated ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.