Trial · NCT01644253
Registered outcomes13
Each outcome the trial registered, primary first, in ClinicalTrials.gov's words.
1 to 13 of 13
Download this page as JSON| List | Outcome | Time frame | Description |
|---|---|---|---|
| Primary | Incidence and severity of adverse events | any time point during the study up to 18 months | |
| Primary | CLL Cysteine 481 mutation status | CLL patients in Cohort 7 will be followed for 9 months unless no cysteine 481 mutation is detected. | The primary endpoint for Cohort 7 is the elimination of the cysteine 481 mutant clone (\<1%). |
| Secondary | Overall Response Rate (ORR) | any time point during the study up to 18 months | |
| Secondary | Progression-free survival (PFS) | any time point during the study up to 18 months | |
| Secondary | Overall survival (OS) | any time point during the study up to 18 months | |
| Secondary | Duration of response (DOR) | any time point during the study up to 18 months | |
| Secondary | Resolution of disease-related symptoms | any time point during the study up to 18 months | Resolution of disease-related symptoms which are common to the disease include fever, weight loss, night sweats, fatigue, loss of appetite pain, and pruritus; symptoms will be assessed by descriptive statistics and data listings. |
| Secondary | Maximum serum drug concentration (Cmax) | any time point during the study up to 12 months | |
| Secondary | Minimum serum drug concentration (Cmin) | any time point during the study up to 12 months | |
| Secondary | Area under the concentration-time curve (AUC0-t and AUC0-∞) | any time point during the study up to 12 months | |
| Secondary | Systemic clearance (CL) | any time point during the study up to 12 months | |
| Secondary | Volume of distribution (Vd) | any time point during the study up to 12 months | |
| Secondary | Elimination half-life (t1/2) | any time point during the study up to 12 months |
Source ClinicalTrials.govtrials-2026-11-12-0.5.0
Sources 3
- ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
- ClinicalTrials.govNo license stated
- NIH RePORTER's clinical studies and project filesPublic domain
Each source's terms
- ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
- ClinicalTrials.govnone stated
- NIH RePORTER's clinical studies and project filesPublic domain (NIH RePORTER)
ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.
For software
Read this list from software.
Twenty rows a page, as JSON. No key.
GET https://conductscience.org/api/trials/v1/NCT01644253/registered