Trial · NCT01696643
Results by group24
Each measurement the trial posted, group by group, in the words and numbers it posted.
1 to 20 of 24
Download this page as JSON| Outcome | Group | Category | Value | Spread | Units |
|---|---|---|---|---|---|
| Percentage of Participants With Treatment-Emergent Adverse Events (TEAEs) | CB-5945 | Had at least 1 TEAE | 58.5 | percentage of participants | |
| Percentage of Participants With Treatment-Emergent Adverse Events (TEAEs) | Placebo | Had at least 1 TEAE | 54.0 | percentage of participants | |
| Percentage of Participants With Treatment-Emergent Adverse Events (TEAEs) | CB-5945 | Had at least 1 drug-related TEAE | 19.9 | percentage of participants | |
| Percentage of Participants With Treatment-Emergent Adverse Events (TEAEs) | Placebo | Had at least 1 drug-related TEAE | 12.1 | percentage of participants | |
| Percentage of Participants With Treatment-Emergent Adverse Events (TEAEs) | CB-5945 | Discontinued treatment due to a TEAE | 10.0 | percentage of participants | |
| Percentage of Participants With Treatment-Emergent Adverse Events (TEAEs) | Placebo | Discontinued treatment due to a TEAE | 5.7 | percentage of participants | |
| Change From Baseline in Mean Daily Opioid Dose at Weeks 49-52 | CB-5945 | -12.456 | Standard Deviation 90.2190 | milligrams of METDD | |
| Change From Baseline in Mean Daily Opioid Dose at Weeks 49-52 | Placebo | -12.297 | Standard Deviation 88.8681 | milligrams of METDD | |
| Change From Baseline in Patient Assessment of Constipation-Quality of Life (PAC-QOL) Questionnaire at Week 52 | CB-5945 | -0.63 | Standard Deviation 0.699 | units on a scale | |
| Change From Baseline in Patient Assessment of Constipation-Quality of Life (PAC-QOL) Questionnaire at Week 52 | Placebo | -0.45 | Standard Deviation 0.583 | units on a scale | |
| Change From Baseline in Patient-Reported Constipation Severity Assessment (PCSA) at Week 52 | CB-5945 | -3.0 | Standard Deviation 3.24 | units on a scale | |
| Change From Baseline in Patient-Reported Constipation Severity Assessment (PCSA) at Week 52 | Placebo | -2.2 | Standard Deviation 3.19 | units on a scale | |
| Plasma Trough Concentrations of CB-5945 | CB-5945 | Week 4 (n=615) | 517.51 | Standard Deviation 403.391 | picograms per milliliter (pg/mL) |
| Plasma Trough Concentrations of CB-5945 | CB-5945 | Week 12 (n=522) | 549.66 | Standard Deviation 425.131 | picograms per milliliter (pg/mL) |
| Plasma Trough Concentrations of CB-5945 | CB-5945 | Week 24 (n=419) | 547.31 | Standard Deviation 453.548 | picograms per milliliter (pg/mL) |
| Plasma Trough Concentrations of CB-5945 | CB-5945 | Week 36 (n=288) | 573.57 | Standard Deviation 517.118 | picograms per milliliter (pg/mL) |
| Plasma Trough Concentrations of CB-5945 | CB-5945 | Week 52 (n=203) | 616.57 | Standard Deviation 725.849 | picograms per milliliter (pg/mL) |
| Plasma Trough Concentrations of CB-5945 | CB-5945 | Overall (n=631) | 517.19 | Standard Deviation 375.963 | picograms per milliliter (pg/mL) |
| Number of Participants With Adjudicated Cardiovascular, Gastrointestinal, or Central Opioid Withdrawal Events | CB-5945 | CV event | 1 | participants | |
| Number of Participants With Adjudicated Cardiovascular, Gastrointestinal, or Central Opioid Withdrawal Events | Placebo | CV event | 2 | participants |
Source ClinicalTrials.govtrials-2026-11-12-0.5.0
Sources 3
- ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
- ClinicalTrials.govNo license stated
- NIH RePORTER's clinical studies and project filesPublic domain
Each source's terms
- ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
- ClinicalTrials.govnone stated
- NIH RePORTER's clinical studies and project filesPublic domain (NIH RePORTER)
ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.
For software
Read this list from software.
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GET https://conductscience.org/api/trials/v1/NCT01696643/results