Trial · NCT01730209
Efficacy of RAD001/Everolimus in Autism and NeuroPsychological Deficits in Children With Tuberous Sclerosis Complex
NCT01730209, Phase 2, Phase 3, Unknown, Erasmus Medical Center
3 sourcestrials-2026-11-12-0.5.0
Cite this record
ConductScience Library. Efficacy of RAD001/Everolimus in Autism and NeuroPsychological Deficits in Children With Tuberous Sclerosis Complex. Trials, record NCT01730209. Release trials-2026-11-12-0.5.0, 12 Nov 2026. https://conductscience.org/library/trials/NCT01730209
On this page
Trial
As registered on ClinicalTrials.gov, in the graph's capture of the registry.
- Title
- Efficacy of RAD001/Everolimus in Autism and NeuroPsychological Deficits in Children With Tuberous Sclerosis Complex
- NCT number
- NCT01730209
- Status
- Unknown
- Phases
- Phase 2, Phase 3
- Enrollment
- 60 participants, estimated
- Lead sponsor
- Erasmus Medical Center
- Conditions
- Tuberous Sclerosis Complex, TSC Related Cognitive Disability, TSC Related Autism, TSC Related Learning Problems
- Interventions
- Everolimus, Placebo
- First posted
- 2012-11-21
- Last updated
- 2015-05-05
Source ClinicalTrials.gov
Registered outcomes14
Each outcome the trial registered, primary first, in ClinicalTrials.gov's words.
| List | Outcome | Time frame | Description |
|---|---|---|---|
| Primary | Cognitive ability measured by IQ | 12 months | Assessed by Wechsler scales: Wechsler Preschool and Primary Scale of Intelligence (WPPSI-III NL) and Wechsler Intelligence Scale for Children (WISC-III-NL) |
| Secondary | Autistic features | 12 Months | Assessed by Autism Diagnostic Observation Schedule (ADOS) |
| Secondary | Social and communicational skills | 12 Months | Assessed by social responsiveness scale (SRS) and Dutch Children's Communication Checklist (CCC-2-NL) questionnaires |
| Secondary | Working memory and attention, information processing | 6 and 12 Months | Assessed by Cambridge Neuropsychological Test Automated Battery (CANTAB) |
| Secondary | Visual-motor integration | 12 Months | Assessed by BEERY Visual-Motor Integration (BEERY VMI), grooved pegboard |
| Secondary | Child behavior | 12 Months | Assessed by Child Behavior Checklist (CBCL) and Teacher's Report Form (TRF) questionnaires |
| Secondary | Executive functioning | 12 Months | Assessed by Behavior Rating Inventory of Executive Functioning (BRIEF) questionnaire Dutch version |
| Secondary | Sleeping problems | 12 Months | Assessed by Sleep Disturbance Scale for Children (SDSC) questionnaire |
| Secondary | Child health | 12 Months | Assessed by Child Health Questionnaire Parent Form (CHQ-PF50) questionnaire |
| Secondary | Sensory related difficulties | 12 Months | Assessed by Short Sensory Profile (SSP) questionnaire |
1 to 10 of 14Source ClinicalTrials.gov
See all 14 registered outcomesOutcomes0
Each outcome the trial posted results for, in ClinicalTrials.gov's words.
None in this release.
Results by group0
Each measurement the trial posted, group by group, in the words and numbers it posted.
None in this release.
Participant flow0
How many started, completed or left each group, period by period.
None in this release.
Adverse events0
Each adverse event the trial posted, group by group: the participants affected out of those at risk.
None in this release.
Adverse event totals0
The totals the trial posted for each group.
None in this release.
Papers1
The papers the trial lists on ClinicalTrials.gov.
| PMID | Listed as |
|---|---|
| 31217257 | DERIVED |
Source PubMed
Grants0
The grants NIH RePORTER links to the trial, newest funded first: NIH's, and some of AHRQ's, CDC's, FDA's and VA's. Each shows its title, principal investigators, organization and funder in its newest year.
None in this release.
Trial comparisons0
Comparisons of the trial's two groups, calculated by ConductScience from the counts it posted.
None in this release.
Tests0
The ConductCognition tests this trial's registered outcomes name, as ScienceGraph matched them in trial-tests-2026-11-12-0.2.1.
None in this release.
Data dates
The day each source was copied for this release.
Sources 3
- ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
- ClinicalTrials.govNo license stated
- NIH RePORTER's clinical studies and project filesPublic domain
Each source's terms
- ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
- ClinicalTrials.govnone stated
- NIH RePORTER's clinical studies and project filesPublic domain (NIH RePORTER)
ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.
For software
Read this trial from software.
The record and each of its lists are JSON, twenty rows a page. No key.
GET https://conductscience.org/api/trials/v1/NCT01730209
GET https://conductscience.org/api/trials/v1/NCT01730209/registered