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Trial · NCT01749098

A Study To Examine The Effects Of PF-04958242 On Ketamine-Induced Cognitive Impairment In Healthy Volunteers

NCT01749098, Phase 1, Completed, Biogen

3 sourcestrials-2026-11-12-0.5.0

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ConductScience Library. A Study To Examine The Effects Of PF-04958242 On Ketamine-Induced Cognitive Impairment In Healthy Volunteers. Trials, record NCT01749098. Release trials-2026-11-12-0.5.0, 12 Nov 2026. https://conductscience.org/library/trials/NCT01749098

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Trial

As registered on ClinicalTrials.gov, in the graph's capture of the registry.

Title
A Study To Examine The Effects Of PF-04958242 On Ketamine-Induced Cognitive Impairment In Healthy Volunteers
NCT number
NCT01749098
Status
Completed
Phases
Phase 1
Enrollment
29 participants, actual
Lead sponsor
Biogen
Conditions
Schizophrenia
Interventions
PF-04958242, Ketamine, Placebo, Ketamine
First posted
2012-12-13
Last updated
2019-11-21

Source ClinicalTrials.gov

Registered outcomes7

Each outcome the trial registered, primary first, in ClinicalTrials.gov's words.

ListOutcomeTime frameDescription
PrimaryTest score on the Hopkins Verbal Learning Test - Immediate RecallDay 5
SecondaryTest score on the Weschler Digit Span TestDay 5
SecondaryTest score on the CogState N-back testDay 5
SecondaryTest score on the CogState Spatial Working memory testDay 5
SecondaryTest score on the CogState One Card Learning testDay 5
SecondaryTest score on the Hopkins Verbal Learning test - Delayed RecallDay 5
SecondaryRetrospective rating on the Positive and Negative Syndrome Scale -modified scale'Day 5

Outcomes0

Each outcome the trial posted results for, in ClinicalTrials.gov's words.

None in this release.

Results by group0

Each measurement the trial posted, group by group, in the words and numbers it posted.

None in this release.

Participant flow0

How many started, completed or left each group, period by period.

None in this release.

Adverse events0

Each adverse event the trial posted, group by group: the participants affected out of those at risk.

None in this release.

Adverse event totals0

The totals the trial posted for each group.

None in this release.

Papers0

The papers the trial lists on ClinicalTrials.gov.

None in this release.

Grants0

The grants NIH RePORTER links to the trial, newest funded first: NIH's, and some of AHRQ's, CDC's, FDA's and VA's. Each shows its title, principal investigators, organization and funder in its newest year.

None in this release.

Trial comparisons0

Comparisons of the trial's two groups, calculated by ConductScience from the counts it posted.

None in this release.

Tests5

The ConductCognition tests this trial's registered outcomes name, as ScienceGraph matched them in trial-tests-2026-11-12-0.2.1.

TestNamed asSource
Verbal LearningPrimary outcomeConductCognition
1-Back TaskSecondary outcomeConductCognition
2-Back TaskSecondary outcomeConductCognition
Digit Span TestSecondary outcomeConductCognition
Spatial Working MemorySecondary outcomeConductCognition

Data dates

The day each source was copied for this release.

ClinicalTrials.gov
2026-11-12
ClinicalTrials.gov
Results, from AACT
2026-03-23
AACT
NIH grant links
2026-11-13
NIH RePORTER

Sources 3

  • ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
  • ClinicalTrials.govNo license stated
  • NIH RePORTER's clinical studies and project filesPublic domain
Each source's terms
  • ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
  • ClinicalTrials.govnone stated
  • NIH RePORTER's clinical studies and project filesPublic domain (NIH RePORTER)

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

For software

Read this trial from software.

The record and each of its lists are JSON, twenty rows a page. No key.

GET https://conductscience.org/api/trials/v1/NCT01749098

GET https://conductscience.org/api/trials/v1/NCT01749098/registered