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Trial · NCT01769196

Results by group36

Each measurement the trial posted, group by group, in the words and numbers it posted.

OutcomeGroupCategoryValueSpreadUnits
Progression Free SurvivalSimtuzumab12.695% Confidence Interval 11.3 to 14.4months
Progression Free SurvivalSimtuzumab Placebo15.495% Confidence Interval 12.6 to 19.1months
PFS Among the Participants With sLOXL2 ≥ 50th PercentileSimtuzumab11.795% Confidence Interval 9.9 to 15.9months
PFS Among the Participants With sLOXL2 ≥ 50th PercentileSimtuzumab Placebo14.395% Confidence Interval 10.4 to 19.1months
PFS Among the Participants With sLOXL2 ≥ 75th PercentileSimtuzumab11.695% Confidence Interval 9.0 to 15.0months
PFS Among the Participants With sLOXL2 ≥ 75th PercentileSimtuzumab Placebo16.995% Confidence Interval 7.7 to 21.7months
Overall Survival (OS)SimtuzumabNA95% Confidence Interval NA to NAmonths
Overall Survival (OS)Simtuzumab PlaceboNA95% Confidence Interval NA to NAmonths
Overall Survival Among the Participants With sLOXL2 ≥ 50th PercentileSimtuzumabNA95% Confidence Interval NA to NAmonths
Overall Survival Among the Participants With sLOXL2 ≥ 50th PercentileSimtuzumab PlaceboNA95% Confidence Interval NA to NAmonths
Overall Survival Among the Participants With sLOXL2 ≥ 75th PercentileSimtuzumabNA95% Confidence Interval 19.2 to NAmonths
Overall Survival Among the Participants With sLOXL2 ≥ 75th PercentileSimtuzumab PlaceboNA95% Confidence Interval NA to NAmonths
Relative Change From Baseline in FVC % PredictedSimtuzumabWeek 54-9.20Standard Error 0.643Percent change in FVC % predicted
Relative Change From Baseline in FVC % PredictedSimtuzumab PlaceboWeek 54-8.88Standard Error 0.658Percent change in FVC % predicted
Relative Change From Baseline in FVC % PredictedSimtuzumabWeek 106-13.70Standard Error 0.883Percent change in FVC % predicted
Relative Change From Baseline in FVC % PredictedSimtuzumab PlaceboWeek 106-12.16Standard Error 0.908Percent change in FVC % predicted
Relative Change From Baseline in FVC % PredictedSimtuzumabWeek 130-18.09Standard Error 1.712Percent change in FVC % predicted
Relative Change From Baseline in FVC % PredictedSimtuzumab PlaceboWeek 130-11.83Standard Error 1.600Percent change in FVC % predicted
Definite Acute Exacerbations of IPF Among Adjudicated Respiratory HospitalizationsSimtuzumab5Participants
Definite Acute Exacerbations of IPF Among Adjudicated Respiratory HospitalizationsSimtuzumab Placebo5Participants

Source ClinicalTrials.govtrials-2026-11-12-0.5.0

Sources 3

  • ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
  • ClinicalTrials.govNo license stated
  • NIH RePORTER's clinical studies and project filesPublic domain
Each source's terms
  • ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
  • ClinicalTrials.govnone stated
  • NIH RePORTER's clinical studies and project filesPublic domain (NIH RePORTER)

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

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