Trial · NCT01785680
Moderate Acute Malnutrition (MAM) and Severe Acute Malnutrition (SAM) in Sierra Leone
NCT01785680, Not applicable, Completed, Washington University School of Medicine; results first posted 2020-03-26
3 sourcestrials-2026-11-12-0.5.0
Cite this record
ConductScience Library. Moderate Acute Malnutrition (MAM) and Severe Acute Malnutrition (SAM) in Sierra Leone. Trials, record NCT01785680. Release trials-2026-11-12-0.5.0, 12 Nov 2026. https://conductscience.org/library/trials/NCT01785680
On this page
Trial
As registered on ClinicalTrials.gov, in the graph's capture of the registry.
- Title
- Moderate Acute Malnutrition (MAM) and Severe Acute Malnutrition (SAM) in Sierra Leone
- NCT number
- NCT01785680
- Status
- Completed
- Phases
- Not applicable
- Enrollment
- 1,957 participants, actual
- Lead sponsor
- Washington University School of Medicine
- Conditions
- Malnutrition
- Interventions
- Integrated Protocol, Current protocol
- First posted
- 2013-02-07
- Last updated
- 2020-03-26
- Results first posted
- 2020-03-26
Source ClinicalTrials.gov
Registered outcomes4
Each outcome the trial registered, primary first, in ClinicalTrials.gov's words.
| List | Outcome | Time frame | Description |
|---|---|---|---|
| Primary | Recovery Under the Integrated Program and the Standard Protocol | 12 weeks | Recovery by the end of treatment standard protocol will be compared to the integrated protocol. Recovery will be defined as mid upper arm circumference (MUAC) reaching ≥12.5 cm. Subjects will return to clinic every 2 weeks until MUAC of 12.5 cm is reached or until 12 weeks has elapsed. |
| Secondary | Change in Growth Rates | 12 weeks | Subjects will return to clinic every 2 weeks until MUAC of 12.5 cm is reached or until 12 weeks has elapsed. Measurement is taken at each visit but final recovery measurement will be used. |
| Secondary | Duration of Treatment | 12 weeks | Subjects will return to clinic every 2 weeks until MUAC of 12.5 cm is reached or until 12 weeks has elapsed. Time to achieve MUAC of 12.5 cm will be documented. |
| Secondary | Change in Recovery Status After 12 Weeks | 6 months | Any changes in recovery will be measured 6 months at follow-up visit. Number of children still well nourished. |
Source ClinicalTrials.gov
Outcomes4
Each outcome the trial posted results for, in ClinicalTrials.gov's words.
| Type | Outcome | Time frame | Population | Units | Measured as |
|---|---|---|---|---|---|
| PRIMARY | Recovery Under the Integrated Program and the Standard Protocol | 12 weeks | Recovery was defined as mid upper arm circumference ≥12.5 cm. | Participants | COUNT_OF_PARTICIPANTS |
| SECONDARY | Change in Growth Rates | 12 weeks | cm | MEAN | |
| SECONDARY | Duration of Treatment | 12 weeks | Number of clinic visits | MEAN | |
| SECONDARY | Change in Recovery Status After 12 Weeks | 6 months | Participants | COUNT_OF_PARTICIPANTS |
Source ClinicalTrials.gov
Results by group8
Each measurement the trial posted, group by group, in the words and numbers it posted.
| Outcome | Group | Category | Value | Spread | Units |
|---|---|---|---|---|---|
| Recovery Under the Integrated Program and the Standard Protocol | Integrated Protocol | 910 | Participants | ||
| Recovery Under the Integrated Program and the Standard Protocol | Current Protocol | 682 | Participants | ||
| Change in Growth Rates | Integrated Protocol | 0.52 | Standard Deviation 0.04 | cm | |
| Change in Growth Rates | Current Protocol | 0.25 | Standard Deviation 0.02 | cm | |
| Duration of Treatment | Integrated Protocol | 2.7 | Standard Deviation 0.06 | Number of clinic visits | |
| Duration of Treatment | Current Protocol | 3.5 | Standard Deviation 0.07 | Number of clinic visits | |
| Change in Recovery Status After 12 Weeks | Integrated Protocol | 544 | Participants | ||
| Change in Recovery Status After 12 Weeks | Current Protocol | 459 | Participants |
Source ClinicalTrials.gov
Participant flow6
How many started, completed or left each group, period by period.
| Period | Milestone | Group | Participants | Units counted |
|---|---|---|---|---|
| Overall Study | STARTED | Integrated Protocol | 1,100 | |
| Overall Study | STARTED | Current Protocol | 857 | |
| Overall Study | COMPLETED | Integrated Protocol | 1,100 | |
| Overall Study | COMPLETED | Current Protocol | 857 | |
| Overall Study | NOT COMPLETED | Integrated Protocol | 0 | |
| Overall Study | NOT COMPLETED | Current Protocol | 0 |
Source ClinicalTrials.gov
Adverse events0
Each adverse event the trial posted, group by group: the participants affected out of those at risk.
None in this release.
Adverse event totals6
The totals the trial posted for each group.
| Total | Group | Affected | At risk |
|---|---|---|---|
| Total, all-cause mortality | Integrated Protocol | 42 | 1,100 |
| Total, all-cause mortality | Current Protocol | 35 | 857 |
| Total, other adverse events | Integrated Protocol | 0 | 1,100 |
| Total, other adverse events | Current Protocol | 0 | 857 |
| Total, serious adverse events | Integrated Protocol | 0 | 1,100 |
| Total, serious adverse events | Current Protocol | 0 | 857 |
Source ClinicalTrials.gov
Papers7
The papers the trial lists on ClinicalTrials.gov.
Grants1
The grants NIH RePORTER links to the trial, newest funded first: NIH's, and some of AHRQ's, CDC's, FDA's and VA's. Each shows its title, principal investigators, organization and funder in its newest year.
| Project | Title | Principal investigators | Organization | Funder | Fiscal years |
|---|---|---|---|---|---|
| U01GH000647 | INTEGRATED PROTOCOL FOR TREATMENT OF MAM AND SAM IN HUMANITARIAN EMERGENCIES | MANARY, MARK JOHN | WASHINGTON UNIVERSITY | Center for Global Health | 2012 to 2013 |
Source NIH RePORTER
Trial comparisons4
Comparisons of the trial's two groups, calculated by ConductScience from the counts it posted.
| Comparison | Source |
|---|---|
| Integrated Protocol vs Current Protocol: Recovery Under the Integrated Program and the Standard Protocol | Trial comparisons |
| Integrated Protocol vs Current Protocol: Change in Recovery Status After 12 Weeks | Trial comparisons |
| Integrated Protocol vs Current Protocol: deaths from any cause | Trial comparisons |
| Integrated Protocol vs Current Protocol: serious adverse events | Trial comparisons |
Tests0
The ConductCognition tests this trial's registered outcomes name, as ScienceGraph matched them in trial-tests-2026-11-12-0.2.1.
None in this release.
Data dates
The day each source was copied for this release.
Sources 3
- ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
- ClinicalTrials.govNo license stated
- NIH RePORTER's clinical studies and project filesPublic domain
Each source's terms
- ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
- ClinicalTrials.govnone stated
- NIH RePORTER's clinical studies and project filesPublic domain (NIH RePORTER)
ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.
For software
Read this trial from software.
The record and each of its lists are JSON, twenty rows a page. No key.
GET https://conductscience.org/api/trials/v1/NCT01785680
GET https://conductscience.org/api/trials/v1/NCT01785680/registered