Trial · NCT01802216
Kidney and Periodontal Disease Study
NCT01802216, Not applicable, Completed, University of California, San Francisco; results first posted 2019-04-30
3 sourcestrials-2026-11-12-0.5.0
Cite this record
ConductScience Library. Kidney and Periodontal Disease Study. Trials, record NCT01802216. Release trials-2026-11-12-0.5.0, 12 Nov 2026. https://conductscience.org/library/trials/NCT01802216
On this page
Trial
As registered on ClinicalTrials.gov, in the graph's capture of the registry.
- Title
- Kidney and Periodontal Disease Study
- NCT number
- NCT01802216
- Status
- Completed
- Phases
- Not applicable
- Enrollment
- 51 participants, actual
- Lead sponsor
- University of California, San Francisco
- Conditions
- Chronic Kidney Disease, Periodontal Disease
- Interventions
- Scaling and root planing, Minocycline
- First posted
- 2013-03-01
- Last updated
- 2019-04-30
- Results first posted
- 2019-04-30
- Limitations and caveats
- A large trial with a true control group is needed to determine the extent to which periodontal treatment may slow the trajectory of kidney function deterioration.
Source ClinicalTrials.gov
Registered outcomes2
Each outcome the trial registered, primary first, in ClinicalTrials.gov's words.
| List | Outcome | Time frame | Description |
|---|---|---|---|
| Primary | Number of Participants Completing Study Protocol | Baseline, Month 4, Month 8, Month 12 | The investigators will determine the number of participants who complete baseline, month 4, month 8, and month 12 study visits. |
| Secondary | Change in Estimated Glomerular Filtration Rate | Baseline, Month 4, Month 12 | Using the creatinine-based CKD-EPI equation, the investigators will determine change in estimated glomerular filtration rate from baseline to 12 month by individual and treatment group |
Source ClinicalTrials.gov
Outcomes2
Each outcome the trial posted results for, in ClinicalTrials.gov's words.
| Type | Outcome | Time frame | Population | Units | Measured as |
|---|---|---|---|---|---|
| PRIMARY | Number of Participants Completing Study Protocol | Baseline, Month 4, Month 8, Month 12 | Participants | COUNT_OF_PARTICIPANTS | |
| SECONDARY | Change in Estimated Glomerular Filtration Rate | Baseline, Month 4, Month 12 | mL/min/1.73m^2 | MEAN |
Source ClinicalTrials.gov
Results by group14
Each measurement the trial posted, group by group, in the words and numbers it posted.
| Outcome | Group | Category | Value | Spread | Units |
|---|---|---|---|---|---|
| Number of Participants Completing Study Protocol | Control/Delayed Treatment | Completed Baseline Visit | 17 | Participants | |
| Number of Participants Completing Study Protocol | Intensive Periodontal Disease Treatment | Completed Baseline Visit | 34 | Participants | |
| Number of Participants Completing Study Protocol | Control/Delayed Treatment | Completed 4 Month Visit | 14 | Participants | |
| Number of Participants Completing Study Protocol | Intensive Periodontal Disease Treatment | Completed 4 Month Visit | 30 | Participants | |
| Number of Participants Completing Study Protocol | Control/Delayed Treatment | Completed 8 Month Visit | 14 | Participants | |
| Number of Participants Completing Study Protocol | Intensive Periodontal Disease Treatment | Completed 8 Month Visit | 29 | Participants | |
| Number of Participants Completing Study Protocol | Control/Delayed Treatment | Completed 12 Month Visit | 14 | Participants | |
| Number of Participants Completing Study Protocol | Intensive Periodontal Disease Treatment | Completed 12 Month Visit | 30 | Participants | |
| Change in Estimated Glomerular Filtration Rate | Control/Delayed Treatment | Baseline Visit | 46.3 | Standard Deviation 10.8 | mL/min/1.73m^2 |
| Change in Estimated Glomerular Filtration Rate | Intensive Periodontal Disease Treatment | Baseline Visit | 43.4 | Standard Deviation 14.7 | mL/min/1.73m^2 |
1 to 10 of 14Source ClinicalTrials.gov
See all 14 results by groupParticipant flow24
How many started, completed or left each group, period by period.
| Period | Milestone | Group | Participants | Units counted |
|---|---|---|---|---|
| Baseline | STARTED | Control/Delayed Treatment | 17 | |
| Baseline | STARTED | Intensive Periodontal Disease Treatment | 34 | |
| Baseline | COMPLETED | Control/Delayed Treatment | 17 | |
| Baseline | COMPLETED | Intensive Periodontal Disease Treatment | 34 | |
| Baseline | NOT COMPLETED | Control/Delayed Treatment | 0 | |
| Baseline | NOT COMPLETED | Intensive Periodontal Disease Treatment | 0 | |
| 4 Month Visit | STARTED | Control/Delayed Treatment | 17 | |
| 4 Month Visit | STARTED | Intensive Periodontal Disease Treatment | 34 | |
| 4 Month Visit | COMPLETED | Control/Delayed Treatment | 14 | |
| 4 Month Visit | COMPLETED | Intensive Periodontal Disease Treatment | 30 |
1 to 10 of 24Source ClinicalTrials.gov
See all 24 participant flowAdverse events2
Each adverse event the trial posted, group by group: the participants affected out of those at risk.
| Type | Event | Organ system | Group | Affected | At risk | Events |
|---|---|---|---|---|---|---|
| serious | Minocycline Reaction | General disorders | Control/Delayed Treatment | 0 | 17 | 0 |
| serious | Minocycline Reaction | General disorders | Intensive Periodontal Disease Treatment | 1 | 34 | 1 |
Source ClinicalTrials.gov
Adverse event totals6
The totals the trial posted for each group.
| Total | Group | Affected | At risk |
|---|---|---|---|
| Total, all-cause mortality | Control/Delayed Treatment | 0 | 17 |
| Total, all-cause mortality | Intensive Periodontal Disease Treatment | 0 | 34 |
| Total, other adverse events | Control/Delayed Treatment | 0 | 17 |
| Total, other adverse events | Intensive Periodontal Disease Treatment | 0 | 34 |
| Total, serious adverse events | Control/Delayed Treatment | 0 | 17 |
| Total, serious adverse events | Intensive Periodontal Disease Treatment | 1 | 34 |
Source ClinicalTrials.gov
Papers1
The papers the trial lists on ClinicalTrials.gov.
| PMID | Listed as |
|---|---|
| 32734226 | DERIVED |
Source PubMed
Grants0
The grants NIH RePORTER links to the trial, newest funded first: NIH's, and some of AHRQ's, CDC's, FDA's and VA's. Each shows its title, principal investigators, organization and funder in its newest year.
None in this release.
Trial comparisons2
Comparisons of the trial's two groups, calculated by ConductScience from the counts it posted.
| Comparison | Source |
|---|---|
| Intensive Periodontal Disease Treatment vs Control/Delayed Treatment: deaths from any cause | Trial comparisons |
| Intensive Periodontal Disease Treatment vs Control/Delayed Treatment: serious adverse events | Trial comparisons |
Tests0
The ConductCognition tests this trial's registered outcomes name, as ScienceGraph matched them in trial-tests-2026-11-12-0.2.1.
None in this release.
Data dates
The day each source was copied for this release.
Sources 3
- ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
- ClinicalTrials.govNo license stated
- NIH RePORTER's clinical studies and project filesPublic domain
Each source's terms
- ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
- ClinicalTrials.govnone stated
- NIH RePORTER's clinical studies and project filesPublic domain (NIH RePORTER)
ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.
For software
Read this trial from software.
The record and each of its lists are JSON, twenty rows a page. No key.
GET https://conductscience.org/api/trials/v1/NCT01802216
GET https://conductscience.org/api/trials/v1/NCT01802216/flow?page=2