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Trial · NCT01808313

Results by group328

Each measurement the trial posted, group by group, in the words and numbers it posted.

OutcomeGroupCategoryValueSpreadUnits
Change From Baseline in 6-minutes Walk Test (6MWT) at Week 12Ambrisentan53.59Standard Deviation 64.494Meters
Change From Baseline in 6MWT at Week 24Ambrisentan64.36Standard Deviation 91.173Meters
Number of Participants With a Change From Baseline in Their World Health Organization (WHO) Functional Classification (FC) at Weeks 12 and 24AmbrisentanImproved by 2 classes at Week 120Participants
Number of Participants With a Change From Baseline in Their World Health Organization (WHO) Functional Classification (FC) at Weeks 12 and 24AmbrisentanImproved by 1 class at Week 1244Participants
Number of Participants With a Change From Baseline in Their World Health Organization (WHO) Functional Classification (FC) at Weeks 12 and 24AmbrisentanNot changing at Week 1284Participants
Number of Participants With a Change From Baseline in Their World Health Organization (WHO) Functional Classification (FC) at Weeks 12 and 24AmbrisentanWorsened by 1 class at Week 124Participants
Number of Participants With a Change From Baseline in Their World Health Organization (WHO) Functional Classification (FC) at Weeks 12 and 24AmbrisentanWorsened by 2 classes at Week 121Participants
Number of Participants With a Change From Baseline in Their World Health Organization (WHO) Functional Classification (FC) at Weeks 12 and 24AmbrisentanImproved by 2 classes at Week 240Participants
Number of Participants With a Change From Baseline in Their World Health Organization (WHO) Functional Classification (FC) at Weeks 12 and 24AmbrisentanImproved by 1 class at Week 2451Participants
Number of Participants With a Change From Baseline in Their World Health Organization (WHO) Functional Classification (FC) at Weeks 12 and 24AmbrisentanNot changing at Week 2477Participants
Number of Participants With a Change From Baseline in Their World Health Organization (WHO) Functional Classification (FC) at Weeks 12 and 24AmbrisentanWorsened by 1 class at Week 243Participants
Number of Participants With a Change From Baseline in Their World Health Organization (WHO) Functional Classification (FC) at Weeks 12 and 24AmbrisentanWorsened by 2 classes at Week 242Participants
Change From Baseline in the Borg Dyspnea Index (BDI) at Weeks 12 and 24AmbrisentanWeek 12-0.34Standard Deviation 1.521scores on a scale
Change From Baseline in the Borg Dyspnea Index (BDI) at Weeks 12 and 24AmbrisentanWeek 24-0.22Standard Deviation 1.952scores on a scale
Change From Baseline in the N-Terminal Pro-B-Type Natriuretic Peptide at Weeks 12 and 24AmbrisentanWeek 12, n=1230.44Standard Deviation 2.687log(ng/L)
Change From Baseline in the N-Terminal Pro-B-Type Natriuretic Peptide at Weeks 12 and 24AmbrisentanWeek 24, n=1220.37Standard Deviation 3.103log(ng/L)
Number of Participants With the Indicated Event, as an Assessment of Time to Clinical Worsening of Pulmonary Arterial Hypertension (PAH) up to Week 24, Assessed as the First Occurrence of a Particular Event
AmbrisentanDeath at Week 122Participants
Number of Participants With the Indicated Event, as an Assessment of Time to Clinical Worsening of Pulmonary Arterial Hypertension (PAH) up to Week 24, Assessed as the First Occurrence of a Particular Event
AmbrisentanLung Transplant at Week 120Participants
Number of Participants With the Indicated Event, as an Assessment of Time to Clinical Worsening of Pulmonary Arterial Hypertension (PAH) up to Week 24, Assessed as the First Occurrence of a Particular Event
AmbrisentanHospitalization for PAH at Week 120Participants
Number of Participants With the Indicated Event, as an Assessment of Time to Clinical Worsening of Pulmonary Arterial Hypertension (PAH) up to Week 24, Assessed as the First Occurrence of a Particular Event
AmbrisentanAtrial Septostomy at Week 120Participants

Source ClinicalTrials.govtrials-2026-11-12-0.5.0

Sources 3

  • ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
  • ClinicalTrials.govNo license stated
  • NIH RePORTER's clinical studies and project filesPublic domain
Each source's terms
  • ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
  • ClinicalTrials.govnone stated
  • NIH RePORTER's clinical studies and project filesPublic domain (NIH RePORTER)

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

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