Trial · NCT01810302
Safety Study of Nicardipine to Treat Cerebral Vasospasm
NCT01810302, Phase 2, Terminated, University of Florida; results first posted 2014-08-29
3 sourcestrials-2026-11-12-0.5.0
Cite this record
ConductScience Library. Safety Study of Nicardipine to Treat Cerebral Vasospasm. Trials, record NCT01810302. Release trials-2026-11-12-0.5.0, 12 Nov 2026. https://conductscience.org/library/trials/NCT01810302
On this page
Trial
As registered on ClinicalTrials.gov, in the graph's capture of the registry.
- Title
- Safety Study of Nicardipine to Treat Cerebral Vasospasm
- NCT number
- NCT01810302
- Status
- Terminated
- Phases
- Phase 2
- Enrollment
- 2 participants, actual
- Lead sponsor
- University of Florida
- Conditions
- Cerebral Vasospasm
- Interventions
- Nicardipine hydrochloride, Preservative-free normal saline
- First posted
- 2013-03-13
- Last updated
- 2014-08-29
- Results first posted
- 2014-08-29
- Limitations and caveats
- This single center study was terminated early due to inability to maintain an adequate drug supply; therefore, statistical analysis of the 2 participants was not done.
Source ClinicalTrials.gov
Registered outcomes2
Each outcome the trial registered, primary first, in ClinicalTrials.gov's words.
| List | Outcome | Time frame | Description |
|---|---|---|---|
| Primary | Number of Participants With Bacterial Meningitis. | Day 1 of study drug until post-hemorrhage day 10. | |
| Secondary | Number of Participants With Cerebral Vasospasm. | Day 1 of study drug until post-hemorrhage day 10. |
Source ClinicalTrials.gov
Outcomes2
Each outcome the trial posted results for, in ClinicalTrials.gov's words.
| Type | Outcome | Time frame | Population | Units | Measured as |
|---|---|---|---|---|---|
| PRIMARY | Number of Participants With Bacterial Meningitis. | Day 1 of study drug until post-hemorrhage day 10. | Number of participants were not sufficient to perform data analysis. | ||
| SECONDARY | Number of Participants With Cerebral Vasospasm. | Day 1 of study drug until post-hemorrhage day 10. | Number of participants were not sufficient to perform data analysis. |
Source ClinicalTrials.gov
Results by group0
Each measurement the trial posted, group by group, in the words and numbers it posted.
None in this release.
Participant flow6
How many started, completed or left each group, period by period.
| Period | Milestone | Group | Participants | Units counted |
|---|---|---|---|---|
| Overall Study | STARTED | Nicardipine Hydrochloride | 1 | |
| Overall Study | STARTED | Preservative-free Normal Saline | 1 | |
| Overall Study | COMPLETED | Nicardipine Hydrochloride | 0 | |
| Overall Study | COMPLETED | Preservative-free Normal Saline | 0 | |
| Overall Study | NOT COMPLETED | Nicardipine Hydrochloride | 1 | |
| Overall Study | NOT COMPLETED | Preservative-free Normal Saline | 1 |
Source ClinicalTrials.gov
Adverse events32
Each adverse event the trial posted, group by group: the participants affected out of those at risk.
| Type | Event | Organ system | Group | Affected | At risk | Events |
|---|---|---|---|---|---|---|
| other | Altered Mental Status | Nervous system disorders | Nicardipine Hydrochloride | 1 | 1 | |
| other | Altered Mental Status | Nervous system disorders | Preservative-free Normal Saline | 1 | 1 | |
| other | Fever | General disorders | Nicardipine Hydrochloride | 1 | 1 | |
| other | Fever | General disorders | Preservative-free Normal Saline | 1 | 1 | |
| other | Hypernatremia | Metabolism and nutrition disorders | Nicardipine Hydrochloride | 1 | 1 | |
| other | Hypernatremia | Metabolism and nutrition disorders | Preservative-free Normal Saline | 0 | 1 | |
| other | Hyponatremia | Metabolism and nutrition disorders | Nicardipine Hydrochloride | 0 | 1 | |
| other | Hyponatremia | Metabolism and nutrition disorders | Preservative-free Normal Saline | 1 | 1 | |
| other | Hypotension | Vascular disorders | Nicardipine Hydrochloride | 1 | 1 | |
| other | Hypotension | Vascular disorders | Preservative-free Normal Saline | 0 | 1 |
1 to 10 of 32Source ClinicalTrials.gov
See all 32 adverse eventsAdverse event totals6
The totals the trial posted for each group.
| Total | Group | Affected | At risk |
|---|---|---|---|
| Total, all-cause mortality | Nicardipine Hydrochloride | ||
| Total, all-cause mortality | Preservative-free Normal Saline | ||
| Total, other adverse events | Nicardipine Hydrochloride | 1 | 1 |
| Total, other adverse events | Preservative-free Normal Saline | 1 | 1 |
| Total, serious adverse events | Nicardipine Hydrochloride | 1 | 1 |
| Total, serious adverse events | Preservative-free Normal Saline | 0 | 1 |
Source ClinicalTrials.gov
Papers0
The papers the trial lists on ClinicalTrials.gov.
None in this release.
Grants0
The grants NIH RePORTER links to the trial, newest funded first: NIH's, and some of AHRQ's, CDC's, FDA's and VA's. Each shows its title, principal investigators, organization and funder in its newest year.
None in this release.
Trial comparisons1
Comparisons of the trial's two groups, calculated by ConductScience from the counts it posted.
| Comparison |
|---|
| Nicardipine Hydrochloride vs Preservative-free Normal Saline: serious adverse events |
Source Trial comparisons
Tests0
The ConductCognition tests this trial's registered outcomes name, as ScienceGraph matched them in trial-tests-2026-11-12-0.2.1.
None in this release.
Data dates
The day each source was copied for this release.
Sources 3
- ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
- ClinicalTrials.govNo license stated
- NIH RePORTER's clinical studies and project filesPublic domain
Each source's terms
- ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
- ClinicalTrials.govnone stated
- NIH RePORTER's clinical studies and project filesPublic domain (NIH RePORTER)
ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.
For software
Read this trial from software.
The record and each of its lists are JSON, twenty rows a page. No key.
GET https://conductscience.org/api/trials/v1/NCT01810302
GET https://conductscience.org/api/trials/v1/NCT01810302/events?page=2