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Trial · NCT01811472

Results by group123

Each measurement the trial posted, group by group, in the words and numbers it posted.

OutcomeGroupCategoryValueSpreadUnits
Change From Baseline in Percentage of Fat in the Liver as Assessed Using MRI at Week 24Placebo0.0095% Confidence Interval -1.63 to 1.63Percentage of liver fat
Change From Baseline in Percentage of Fat in the Liver as Assessed Using MRI at Week 24Pradigastat (LCQ908) 5mg/10mg-1.6895% Confidence Interval -3.93 to 0.56Percentage of liver fat
Change From Baseline in Percentage of Fat in the Liver as Assessed Using MRI at Week 24Pradigastat (LCQ908) 10mg/20mg-2.8995% Confidence Interval -4.59 to -1.18Percentage of liver fat
Change From Baseline in Percentage of Fat in the Liver as Assessed Using MRI at Week 12Placebo-0.8090% Confidence Interval -2.31 to 0.72Percentage of liver fat
Change From Baseline in Percentage of Fat in the Liver as Assessed Using MRI at Week 12Pradigastat (LCQ908) 5mg/10mg-1.7190% Confidence Interval -3.79 to 0.37Percentage of liver fat
Change From Baseline in Percentage of Fat in the Liver as Assessed Using MRI at Week 12Pradigastat (LCQ908) 10mg/20mg-2.9890% Confidence Interval -4.55 to -1.42Percentage of liver fat
Percentage of Responders at Week 12PlaceboAt least 30% reduction in percent liver fat10.00Percentage of responders
Percentage of Responders at Week 12Pradigastat (LCQ908) 5mg/10mgAt least 30% reduction in percent liver fat18.18Percentage of responders
Percentage of Responders at Week 12Pradigastat (LCQ908) 10mg/20mgAt least 30% reduction in percent liver fat31.58Percentage of responders
Percentage of Responders at Week 12PlaceboAt least 50% reduction in percent liver fat5.00Percentage of responders
Percentage of Responders at Week 12Pradigastat (LCQ908) 5mg/10mgAt least 50% reduction in percent liver fat0.00Percentage of responders
Percentage of Responders at Week 12Pradigastat (LCQ908) 10mg/20mgAt least 50% reduction in percent liver fat21.05Percentage of responders
Percentage of Responders at Week 12PlaceboLiver fat content < 10%5.00Percentage of responders
Percentage of Responders at Week 12Pradigastat (LCQ908) 5mg/10mgLiver fat content < 10%18.18Percentage of responders
Percentage of Responders at Week 12Pradigastat (LCQ908) 10mg/20mgLiver fat content < 10%36.84Percentage of responders
Percentage of Responders at Week 12PlaceboLiver fat content <5.6%0.00Percentage of responders
Percentage of Responders at Week 12Pradigastat (LCQ908) 5mg/10mgLiver fat content <5.6%0.00Percentage of responders
Percentage of Responders at Week 12Pradigastat (LCQ908) 10mg/20mgLiver fat content <5.6%21.05Percentage of responders
Percentage of Responders at Week 24PlaceboAt least 30% reduction in percent liver fat10.53Percentage of responders
Percentage of Responders at Week 24Pradigastat (LCQ908) 5mg/10mgAt least 30% reduction in percent liver fat30.00Percentage of responders

Source ClinicalTrials.govtrials-2026-11-12-0.5.0

Sources 3

  • ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
  • ClinicalTrials.govNo license stated
  • NIH RePORTER's clinical studies and project filesPublic domain
Each source's terms
  • ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
  • ClinicalTrials.govnone stated
  • NIH RePORTER's clinical studies and project filesPublic domain (NIH RePORTER)

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

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