Trial · NCT01813058
Does Tranexamic Acid Decrease Blood Loss in Pediatric Idiopathic Scoliosis Surgery?
NCT01813058, Phase 1, Phase 2, Completed, Boston Children's Hospital; results first posted 2019-02-20
3 sourcestrials-2026-11-12-0.5.0
Cite this record
ConductScience Library. Does Tranexamic Acid Decrease Blood Loss in Pediatric Idiopathic Scoliosis Surgery? Trials, record NCT01813058. Release trials-2026-11-12-0.5.0, 12 Nov 2026. https://conductscience.org/library/trials/NCT01813058
On this page
Trial
As registered on ClinicalTrials.gov, in the graph's capture of the registry.
- Title
- Does Tranexamic Acid Decrease Blood Loss in Pediatric Idiopathic Scoliosis Surgery?
- NCT number
- NCT01813058
- Status
- Completed
- Phases
- Phase 1, Phase 2
- Enrollment
- 120 participants, actual
- Lead sponsor
- Boston Children's Hospital
- Conditions
- Adolescent Idiopathic Scoliosis
- Interventions
- Tranexamic Acid, Placebo
- First posted
- 2013-03-18
- Last updated
- 2019-02-20
- Results first posted
- 2019-02-20
Source ClinicalTrials.gov
Registered outcomes1
Each outcome the trial registered, primary first, in ClinicalTrials.gov's words.
| List | Outcome | Time frame | Description |
|---|---|---|---|
| Primary | Perioperative Blood Loss | perioperarively - during entire hospital admission | Perioperative blood loss (during operation and for entire hospital admission) |
Source ClinicalTrials.gov
Outcomes1
Each outcome the trial posted results for, in ClinicalTrials.gov's words.
| Type | Outcome | Time frame | Population | Units | Measured as |
|---|---|---|---|---|---|
| PRIMARY | Perioperative Blood Loss | perioperarively - during entire hospital admission | mL | MEAN |
Source ClinicalTrials.gov
Results by group2
Each measurement the trial posted, group by group, in the words and numbers it posted.
| Outcome | Group | Category | Value | Spread | Units |
|---|---|---|---|---|---|
| Perioperative Blood Loss | Placebo | 1031 | Standard Deviation 484 | mL | |
| Perioperative Blood Loss | Tranexamic Acid | 836 | Standard Deviation 373 | mL |
Source ClinicalTrials.gov
Participant flow6
How many started, completed or left each group, period by period.
| Period | Milestone | Group | Participants | Units counted |
|---|---|---|---|---|
| Overall Study | STARTED | Placebo | 60 | |
| Overall Study | STARTED | Tranexamic Acid | 60 | |
| Overall Study | COMPLETED | Placebo | 55 | |
| Overall Study | COMPLETED | Tranexamic Acid | 56 | |
| Overall Study | NOT COMPLETED | Placebo | 5 | |
| Overall Study | NOT COMPLETED | Tranexamic Acid | 4 |
Source ClinicalTrials.gov
Adverse events0
Each adverse event the trial posted, group by group: the participants affected out of those at risk.
None in this release.
Adverse event totals6
The totals the trial posted for each group.
| Total | Group | Affected | At risk |
|---|---|---|---|
| Total, all-cause mortality | Placebo | 0 | 55 |
| Total, all-cause mortality | Tranexamic Acid | 0 | 56 |
| Total, other adverse events | Placebo | 0 | 55 |
| Total, other adverse events | Tranexamic Acid | 0 | 56 |
| Total, serious adverse events | Placebo | 0 | 55 |
| Total, serious adverse events | Tranexamic Acid | 0 | 56 |
Source ClinicalTrials.gov
Papers3
The papers the trial lists on ClinicalTrials.gov.
Grants0
The grants NIH RePORTER links to the trial, newest funded first: NIH's, and some of AHRQ's, CDC's, FDA's and VA's. Each shows its title, principal investigators, organization and funder in its newest year.
None in this release.
Trial comparisons2
Comparisons of the trial's two groups, calculated by ConductScience from the counts it posted.
| Comparison | Source |
|---|---|
| Tranexamic Acid vs Placebo: deaths from any cause | Trial comparisons |
| Tranexamic Acid vs Placebo: serious adverse events | Trial comparisons |
Tests0
The ConductCognition tests this trial's registered outcomes name, as ScienceGraph matched them in trial-tests-2026-11-12-0.2.1.
None in this release.
Data dates
The day each source was copied for this release.
Sources 3
- ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
- ClinicalTrials.govNo license stated
- NIH RePORTER's clinical studies and project filesPublic domain
Each source's terms
- ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
- ClinicalTrials.govnone stated
- NIH RePORTER's clinical studies and project filesPublic domain (NIH RePORTER)
ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.
For software
Read this trial from software.
The record and each of its lists are JSON, twenty rows a page. No key.
GET https://conductscience.org/api/trials/v1/NCT01813058
GET https://conductscience.org/api/trials/v1/NCT01813058/registered