Phase 3 Study of Ataluren in Participants With Nonsense Mutation Duchenne Muscular Dystrophy (nmDMD)
Trial · NCT01826487
Results by group120
Each measurement the trial posted, group by group, in the words and numbers it posted.
1 to 20 of 120
Download this page as JSON| Outcome | Group | Category | Value | Spread | Units |
|---|---|---|---|---|---|
| Change From Baseline in 6MWD at Week 48 | Placebo | -60.67 | Standard Error 9.323 | meters | |
| Change From Baseline in 6MWD at Week 48 | Ataluren | -47.69 | Standard Error 9.247 | meters | |
| Time to 10 Percent (%) Persistent Worsening in 6MWD | Placebo | <300 meters | 56 | 95% Confidence Interval 1.0 to 111.0 | days |
| Time to 10 Percent (%) Persistent Worsening in 6MWD | Ataluren | <300 meters | 164 | 95% Confidence Interval 1.0 to 225.0 | days |
| Time to 10 Percent (%) Persistent Worsening in 6MWD | Placebo | >=300 to <400 meters | 280 | 95% Confidence Interval 169.0 to NA | days |
| Time to 10 Percent (%) Persistent Worsening in 6MWD | Ataluren | >=300 to <400 meters | NA | 95% Confidence Interval 280.0 to NA | days |
| Time to 10 Percent (%) Persistent Worsening in 6MWD | Placebo | >=400 meters | NA | 95% Confidence Interval NA to NA | days |
| Time to 10 Percent (%) Persistent Worsening in 6MWD | Ataluren | >=400 meters | NA | 95% Confidence Interval NA to NA | days |
| Change From Baseline in Time to Walk/Run 10 Meters at Week 48 | Placebo | 3.47 | Standard Deviation 6.393 | seconds | |
| Change From Baseline in Time to Walk/Run 10 Meters at Week 48 | Ataluren | 2.27 | Standard Deviation 5.216 | seconds | |
| Change From Baseline in Time to Climb 4 Stairs at Week 48 | Placebo | 4.46 | Standard Deviation 7.310 | seconds | |
| Change From Baseline in Time to Climb 4 Stairs at Week 48 | Ataluren | 2.65 | Standard Deviation 5.297 | seconds | |
| Change From Baseline in Time to Descend 4 Stairs at Week 48 | Placebo | 3.97 | Standard Deviation 7.854 | seconds | |
| Change From Baseline in Time to Descend 4 Stairs at Week 48 | Ataluren | 2.15 | Standard Deviation 5.306 | seconds | |
| Change From Baseline in Physical Function Total Score as Measured by NSAA at Week 48 | Placebo | -8.4 | Standard Deviation 10.65 | units on a scale | |
| Change From Baseline in Physical Function Total Score as Measured by NSAA at Week 48 | Ataluren | -6.3 | Standard Deviation 10.64 | units on a scale | |
| Number of Participants With Change From Baseline in Activities of Daily Living and Disease Status at Week 48, as Assessed by a Standardized Survey Administered by Site Personnel | Placebo | Physical Functioning: Upper Extremity Activity / Much better | 1 | Participants | |
| Number of Participants With Change From Baseline in Activities of Daily Living and Disease Status at Week 48, as Assessed by a Standardized Survey Administered by Site Personnel | Ataluren | Physical Functioning: Upper Extremity Activity / Much better | 4 | Participants | |
| Number of Participants With Change From Baseline in Activities of Daily Living and Disease Status at Week 48, as Assessed by a Standardized Survey Administered by Site Personnel | Placebo | Physical Functioning: Upper Extremity Activity / Slightly better | 7 | Participants | |
| Number of Participants With Change From Baseline in Activities of Daily Living and Disease Status at Week 48, as Assessed by a Standardized Survey Administered by Site Personnel | Ataluren | Physical Functioning: Upper Extremity Activity / Slightly better | 7 | Participants |
Source ClinicalTrials.govtrials-2026-11-12-0.5.0
Sources 3
- ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
- ClinicalTrials.govNo license stated
- NIH RePORTER's clinical studies and project filesPublic domain
Each source's terms
- ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
- ClinicalTrials.govnone stated
- NIH RePORTER's clinical studies and project filesPublic domain (NIH RePORTER)
ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.
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GET https://conductscience.org/api/trials/v1/NCT01826487/results