Trial · NCT01857856
PHOspholamban RElated CArdiomyopathy STudy - Intervention
NCT01857856, Phase 3, Completed, M.p. van den Berg, MD, PhD, professor in Cardiology
3 sourcestrials-2026-11-12-0.5.0
Cite this record
ConductScience Library. PHOspholamban RElated CArdiomyopathy STudy - Intervention. Trials, record NCT01857856. Release trials-2026-11-12-0.5.0, 12 Nov 2026. https://conductscience.org/library/trials/NCT01857856
On this page
Trial
As registered on ClinicalTrials.gov, in the graph's capture of the registry.
- Title
- PHOspholamban RElated CArdiomyopathy STudy - Intervention
- NCT number
- NCT01857856
- Status
- Completed
- Phases
- Phase 3
- Enrollment
- 84 participants, actual
- Lead sponsor
- M.p. van den Berg, MD, PhD, professor in Cardiology
- Conditions
- Phospholamban R14del Mutation-related Cardiomyopathy
- Interventions
- Eplerenone
- First posted
- 2013-05-20
- Last updated
- 2021-10-18
- Other registries' IDs
- eudract:2013-001067-23
Source ClinicalTrials.gov
Registered outcomes19
Each outcome the trial registered, primary first, in ClinicalTrials.gov's words.
| List | Outcome | Time frame | Description |
|---|---|---|---|
| Primary | Left ventricular (LV) enddiastolic volume, increase >10%, as measured by MRI | three years | |
| Primary | LV ejection fraction, absolute decrease >5%, as measured by MRI | three years | |
| Primary | Right ventricular (RV) enddiastolic volume, increase >10%, as measured by MRI | three years | |
| Primary | RV ejection fraction, absolute decrease >5%, as measured by MRI | three years | |
| Primary | late gadolinium enhancement, absolute increase >5%, as measured by MRI | three years | |
| Primary | Change in ventricular premature complexes, increase >100% in combination with absolute number >1000/24 hrs (Holter monitoring) | yearly at 0, 1, 2 and 3 years | |
| Primary | Change in the occurrence of non-sustained ventricular tachycardia (Holter monitoring, exercise testing) | yearly at 0, 1, 2 and 3 years | |
| Primary | Change in QRS voltage, decrease >25% (ECG) | yearly at 0,1,2 and 3 years | |
| Primary | Change in symptoms/signs of heart failure and/or arrhythmias necessitating treatment according to the attending physician and likely due to arrhythmogenic cardiomyopathy | yearly at 0,1,2 and 3 years, and possibly in between at referral | |
| Primary | (Change in) cardiovascular death, including sudden death, likely due to arrhythmogenic cardiomyopathy | yearly at 0,1,2 and 3 years, and possibly in between at referral |
1 to 10 of 19Source ClinicalTrials.gov
See all 19 registered outcomesOutcomes0
Each outcome the trial posted results for, in ClinicalTrials.gov's words.
None in this release.
Results by group0
Each measurement the trial posted, group by group, in the words and numbers it posted.
None in this release.
Participant flow0
How many started, completed or left each group, period by period.
None in this release.
Adverse events0
Each adverse event the trial posted, group by group: the participants affected out of those at risk.
None in this release.
Adverse event totals0
The totals the trial posted for each group.
None in this release.
Papers7
The papers the trial lists on ClinicalTrials.gov.
Grants0
The grants NIH RePORTER links to the trial, newest funded first: NIH's, and some of AHRQ's, CDC's, FDA's and VA's. Each shows its title, principal investigators, organization and funder in its newest year.
None in this release.
Trial comparisons0
Comparisons of the trial's two groups, calculated by ConductScience from the counts it posted.
None in this release.
Tests0
The ConductCognition tests this trial's registered outcomes name, as ScienceGraph matched them in trial-tests-2026-11-12-0.2.1.
None in this release.
Data dates
The day each source was copied for this release.
Sources 3
- ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
- ClinicalTrials.govNo license stated
- NIH RePORTER's clinical studies and project filesPublic domain
Each source's terms
- ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
- ClinicalTrials.govnone stated
- NIH RePORTER's clinical studies and project filesPublic domain (NIH RePORTER)
ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.
For software
Read this trial from software.
The record and each of its lists are JSON, twenty rows a page. No key.
GET https://conductscience.org/api/trials/v1/NCT01857856
GET https://conductscience.org/api/trials/v1/NCT01857856/registered