Trial · NCT01875445

Inositol in Trichotillomania

NCT01875445, Phase 2, Completed, University of Chicago; results first posted 2017-05-19

3 sourcestrials-2026-11-12-0.5.0

Cite this record

ConductScience Library. Inositol in Trichotillomania. Trials, record NCT01875445. Release trials-2026-11-12-0.5.0, 12 Nov 2026. https://conductscience.org/library/trials/NCT01875445

On this page

Trial

As registered on ClinicalTrials.gov, in the graph's capture of the registry.

Title: Inositol in Trichotillomania
NCT number: NCT01875445
Status: Completed
Phases: Phase 2
Enrollment: 38 participants, actual
Lead sponsor: University of Chicago
Conditions: Trichotillomania, Hair Pulling
Interventions: Inositol, Placebo
First posted: 2013-06-11
Last updated: 2023-02-23
Results first posted: 2017-05-19

Source ClinicalTrials.gov

Registered outcomes2

Each outcome the trial registered, primary first, in ClinicalTrials.gov's words.

List	Outcome	Time frame	Description
Primary	The National Institute of Mental Health Trichotillomania Symptom Severity Scale (NIMH-TSS)	Once every two weeks for the 10 weeks of the study	The entire study for an individual subject will last 10 weeks. Every 2 weeks the subject will take the NIMH-TSS for the duration of the 10 weeks, but only baseline and final values will be used for general final outcome assessment. The scale itself asses severity of hair pulling.
Secondary	The Massachusetts General Hospital (MGH) Hairpulling Scale	Once every two weeks for the 10 weeks of the study	The entire study for an individual subject will last 10 weeks. Every 2 weeks the subject will take the MGH Hairpulling Scale for the duration of the 10 weeks, baseline and final visits will be use for general final outcome assessment. The scale itself asses severity of hair pulling.

Source ClinicalTrials.gov

Outcomes2

Each outcome the trial posted results for, in ClinicalTrials.gov's words.

Type	Outcome	Time frame	Population	Units	Measured as
PRIMARY	The National Institute of Mental Health Trichotillomania Symptom Severity Scale (NIMH-TSS)	Once every two weeks for the 10 weeks of the study	Last observation carried forward for general means.	units on a scale	MEAN
SECONDARY	The Massachusetts General Hospital (MGH) Hairpulling Scale	Once every two weeks for the 10 weeks of the study	Last observation carried forwards for general averages.	units on a scale	MEAN

Source ClinicalTrials.gov

Results by group4

Each measurement the trial posted, group by group, in the words and numbers it posted.

Outcome	Group	Value	Spread	Units
The National Institute of Mental Health Trichotillomania Symptom Severity Scale (NIMH-TSS)	Placebo	8.4	Standard Deviation 5.5	units on a scale
The National Institute of Mental Health Trichotillomania Symptom Severity Scale (NIMH-TSS)	Inositol	8.4	Standard Deviation 5.1	units on a scale
The Massachusetts General Hospital (MGH) Hairpulling Scale	Placebo	14.5	Standard Deviation 5.1	units on a scale
The Massachusetts General Hospital (MGH) Hairpulling Scale	Inositol	13.2	Standard Deviation 6.8	units on a scale

Source ClinicalTrials.gov

Participant flow6

How many started, completed or left each group, period by period.

Period	Milestone	Group	Participants
Overall Study	STARTED	Placebo	19
Overall Study	STARTED	Inositol	19
Overall Study	COMPLETED	Placebo	12
Overall Study	COMPLETED	Inositol	19
Overall Study	NOT COMPLETED	Placebo	7
Overall Study	NOT COMPLETED	Inositol	0

Source ClinicalTrials.gov

Adverse events12

Each adverse event the trial posted, group by group: the participants affected out of those at risk.

Type	Event	Organ system	Group	Affected	At risk	Events
other	Nausea/Upset Stomach	Gastrointestinal disorders	Placebo	2	19	3
other	Nausea/Upset Stomach	Gastrointestinal disorders	Inositol	4	19	6
other	Stomach Pain	Gastrointestinal disorders	Placebo	0	19	0
other	Stomach Pain	Gastrointestinal disorders	Inositol	2	19	2
other	Headache	General disorders	Placebo	2	19	2
other	Headache	General disorders	Inositol	2	19	2
other	Diarrhea	Gastrointestinal disorders	Placebo	0	19	0
other	Diarrhea	Gastrointestinal disorders	Inositol	2	19	2
other	Gas	Gastrointestinal disorders	Placebo	0	19	0
other	Gas	Gastrointestinal disorders	Inositol	1	19	1

1 to 10 of 12Source ClinicalTrials.gov

See all 12 adverse events

Adverse event totals6

The totals the trial posted for each group.

Total	Group	Affected	At risk
Total, all-cause mortality	Placebo	0	19
Total, all-cause mortality	Inositol	0	19
Total, other adverse events	Placebo	4	19
Total, other adverse events	Inositol	9	19
Total, serious adverse events	Placebo	0	19
Total, serious adverse events	Inositol	1	19

Source ClinicalTrials.gov

Papers1

The papers the trial lists on ClinicalTrials.gov.

PMID	Listed as
34582562	DERIVED

Source PubMed

Grants0

The grants NIH RePORTER links to the trial, newest funded first: NIH's, and some of AHRQ's, CDC's, FDA's and VA's. Each shows its title, principal investigators, organization and funder in its newest year.

None in this release.

Trial comparisons2

Comparisons of the trial's two groups, calculated by ConductScience from the counts it posted.

Comparison	Source
Inositol vs Placebo: deaths from any cause	Trial comparisons
Inositol vs Placebo: serious adverse events	Trial comparisons

Tests0

The ConductCognition tests this trial's registered outcomes name, as ScienceGraph matched them in trial-tests-2026-11-12-0.2.1.

None in this release.

Data dates

The day each source was copied for this release.

ClinicalTrials.gov: 2026-11-12; ClinicalTrials.gov
Results, from AACT: 2026-03-23; AACT
NIH grant links: 2026-11-13; NIH RePORTER

Sources 3

ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
ClinicalTrials.govNo license stated
NIH RePORTER's clinical studies and project filesPublic domain

Each source's terms

ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
ClinicalTrials.govnone stated
NIH RePORTER's clinical studies and project filesPublic domain (NIH RePORTER)

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

For software

Read this trial from software.

The record and each of its lists are JSON, twenty rows a page. No key.

GET https://conductscience.org/api/trials/v1/NCT01875445

GET https://conductscience.org/api/trials/v1/NCT01875445/registered

API reference For AI assistants