Trial · NCT01881568
Efficacy Comparison of Topical and Intravenous Tranexamic Acid to Reduce the Number of Blood Transfusions in TKA
NCT01881568, Phase 3, Completed, Hospital Universitario La Paz
3 sourcestrials-2026-11-12-0.5.0
Cite this record
ConductScience Library. Efficacy Comparison of Topical and Intravenous Tranexamic Acid to Reduce the Number of Blood Transfusions in TKA. Trials, record NCT01881568. Release trials-2026-11-12-0.5.0, 12 Nov 2026. https://conductscience.org/library/trials/NCT01881568
On this page
Trial
As registered on ClinicalTrials.gov, in the graph's capture of the registry.
- Title
- Efficacy Comparison of Topical and Intravenous Tranexamic Acid to Reduce the Number of Blood Transfusions in TKA
- NCT number
- NCT01881568
- Status
- Completed
- Phases
- Phase 3
- Enrollment
- 79 participants, actual
- Lead sponsor
- Hospital Universitario La Paz
- Conditions
- Blood Loss
- Interventions
- Tranexamic Acid, Tranexamic Acid
- First posted
- 2013-06-19
- Last updated
- 2014-12-03
Source ClinicalTrials.gov
Registered outcomes9
Each outcome the trial registered, primary first, in ClinicalTrials.gov's words.
| List | Outcome | Time frame | Description |
|---|---|---|---|
| Primary | Blood transfusion rate | participants will be followed for the duration of hospital stay, an expected average of 5 days | Number of transfused patients in each arm/Total number of patients in each arm |
| Secondary | Visible blood loss | 24 hours after surgery | Number of milliliters drained in Redon after 24 hours post OP |
| Secondary | Invisible blood loss | 48 hours after surgery | Number of milliliters estimated with Nedler formula 48 hours after surgery. Invisible blood loss= 75\*weight(Kg)\*\[(Hb0-Hb1)/Hb0\]+ blood transfused(mL) |
| Secondary | Surgery infection rate | One month after surgery | * Percent of patients with proved signs of infection during the hospital stay * Percent of patients with proved signs of infection one month after surgery(safety reasons) |
| Secondary | Range of motion | participants will be followed for the duration of hospital stay, an expected average of 5 days | \- Range (in degrees) from full extension to full flexion during the hospital stay |
| Secondary | Prevalence of drug-related adverse events | participants will be followed for the duration of hospital stay, an expected average of 5 days | Rate and characteristics of the adverse events during the hospital stay |
| Secondary | Rate of PE | One month after surgery | * Percent of PE during the hospital stay * Percent of PE one month after surgery(safety reasons) |
| Secondary | Rate of DVT | One month after surgery | * Percent of DVT during the hospital stay * Percent of DVT one month after surgery(safety reasons) |
| Secondary | Rate or Thrombophlebitis | One month after surgery | * Percent of Thrombophlebitis during the hospital stay * Percent of Thrombophlebitis one month after surgery(safety reasons) |
Source ClinicalTrials.gov
Outcomes0
Each outcome the trial posted results for, in ClinicalTrials.gov's words.
None in this release.
Results by group0
Each measurement the trial posted, group by group, in the words and numbers it posted.
None in this release.
Participant flow0
How many started, completed or left each group, period by period.
None in this release.
Adverse events0
Each adverse event the trial posted, group by group: the participants affected out of those at risk.
None in this release.
Adverse event totals0
The totals the trial posted for each group.
None in this release.
Papers1
The papers the trial lists on ClinicalTrials.gov.
| PMID | Listed as |
|---|---|
| 25471907 | DERIVED |
Source PubMed
Grants0
The grants NIH RePORTER links to the trial, newest funded first: NIH's, and some of AHRQ's, CDC's, FDA's and VA's. Each shows its title, principal investigators, organization and funder in its newest year.
None in this release.
Trial comparisons0
Comparisons of the trial's two groups, calculated by ConductScience from the counts it posted.
None in this release.
Tests0
The ConductCognition tests this trial's registered outcomes name, as ScienceGraph matched them in trial-tests-2026-11-12-0.2.1.
None in this release.
Data dates
The day each source was copied for this release.
Sources 3
- ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
- ClinicalTrials.govNo license stated
- NIH RePORTER's clinical studies and project filesPublic domain
Each source's terms
- ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
- ClinicalTrials.govnone stated
- NIH RePORTER's clinical studies and project filesPublic domain (NIH RePORTER)
ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.
For software
Read this trial from software.
The record and each of its lists are JSON, twenty rows a page. No key.
GET https://conductscience.org/api/trials/v1/NCT01881568
GET https://conductscience.org/api/trials/v1/NCT01881568/registered