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Trial · NCT01916941

Neural Mechanisms of Change During the Treatment of Alcohol Use Disorders With Prazosin

NCT01916941, Not applicable, Completed, University of New Mexico; results first posted 2017-10-17

3 sourcestrials-2026-11-12-0.5.0

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ConductScience Library. Neural Mechanisms of Change During the Treatment of Alcohol Use Disorders With Prazosin. Trials, record NCT01916941. Release trials-2026-11-12-0.5.0, 12 Nov 2026. https://conductscience.org/library/trials/NCT01916941

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Trial

As registered on ClinicalTrials.gov, in the graph's capture of the registry.

Title
Neural Mechanisms of Change During the Treatment of Alcohol Use Disorders With Prazosin
NCT number
NCT01916941
Status
Completed
Phases
Not applicable
Enrollment
36 participants, actual
Lead sponsor
University of New Mexico
Conditions
Alcohol Use Disorder
Interventions
Prazosin, Placebo
First posted
2013-08-06
Last updated
2017-10-17
Results first posted
2017-10-17

Source ClinicalTrials.gov

Registered outcomes1

Each outcome the trial registered, primary first, in ClinicalTrials.gov's words.

ListOutcomeTime frameDescription
PrimaryNumber of Standard Alcoholic Drinks Consumed Per Week (Drinks Per Week)from 2-4 weeks and from 4-6 weeks

Outcomes1

Each outcome the trial posted results for, in ClinicalTrials.gov's words.

TypeOutcomeTime framePopulationUnitsMeasured as
PRIMARYNumber of Standard Alcoholic Drinks Consumed Per Week (Drinks Per Week)from 2-4 weeks and from 4-6 weeksdrinks per weekMEAN

Results by group4

Each measurement the trial posted, group by group, in the words and numbers it posted.

OutcomeGroupCategoryValueSpreadUnits
Number of Standard Alcoholic Drinks Consumed Per Week (Drinks Per Week)Prazosinfrom 2-4 weeks13.65Standard Deviation 18.92drinks per week
Number of Standard Alcoholic Drinks Consumed Per Week (Drinks Per Week)Placebofrom 2-4 weeks14.55Standard Deviation 17.29drinks per week
Number of Standard Alcoholic Drinks Consumed Per Week (Drinks Per Week)Prazosinfrom 4-6 weeks15.11Standard Deviation 23.66drinks per week
Number of Standard Alcoholic Drinks Consumed Per Week (Drinks Per Week)Placebofrom 4-6 weeks11.11Standard Deviation 15.01drinks per week

Participant flow6

How many started, completed or left each group, period by period.

PeriodMilestoneGroupParticipantsUnits counted
Overall StudySTARTEDPrazosin18
Overall StudySTARTEDPlacebo18
Overall StudyCOMPLETEDPrazosin13
Overall StudyCOMPLETEDPlacebo14
Overall StudyNOT COMPLETEDPrazosin5
Overall StudyNOT COMPLETEDPlacebo4

Adverse events2

Each adverse event the trial posted, group by group: the participants affected out of those at risk.

TypeEventOrgan systemGroupAffectedAt riskEvents
otherDizziness on standingCardiac disordersPrazosin1018
otherDizziness on standingCardiac disordersPlacebo418

Adverse event totals6

The totals the trial posted for each group.

TotalGroupAffectedAt risk
Total, all-cause mortalityPrazosin
Total, all-cause mortalityPlacebo
Total, other adverse eventsPrazosin1018
Total, other adverse eventsPlacebo418
Total, serious adverse eventsPrazosin018
Total, serious adverse eventsPlacebo018

Papers0

The papers the trial lists on ClinicalTrials.gov.

None in this release.

Grants1

The grants NIH RePORTER links to the trial, newest funded first: NIH's, and some of AHRQ's, CDC's, FDA's and VA's. Each shows its title, principal investigators, organization and funder in its newest year.

ProjectTitlePrincipal investigatorsOrganizationFunderFiscal years
K23AA021156Neural Mechanisms of Change During Alcohol Use DisorderTreatment with PrazosinWILCOX, CLAIREUNIVERSITY OF NEW MEXICO HEALTH SCIS CTRNATIONAL INSTITUTE ON ALCOHOL ABUSE AND ALCOHOLISM2013 to 2017

Trial comparisons1

Comparisons of the trial's two groups, calculated by ConductScience from the counts it posted.

Comparison
Prazosin vs Placebo: serious adverse events

Tests0

The ConductCognition tests this trial's registered outcomes name, as ScienceGraph matched them in trial-tests-2026-11-12-0.2.1.

None in this release.

Data dates

The day each source was copied for this release.

ClinicalTrials.gov
2026-11-12
ClinicalTrials.gov
Results, from AACT
2026-03-23
AACT
NIH grant links
2026-11-13
NIH RePORTER

Sources 3

  • ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
  • ClinicalTrials.govNo license stated
  • NIH RePORTER's clinical studies and project filesPublic domain
Each source's terms
  • ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
  • ClinicalTrials.govnone stated
  • NIH RePORTER's clinical studies and project filesPublic domain (NIH RePORTER)

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

For software

Read this trial from software.

The record and each of its lists are JSON, twenty rows a page. No key.

GET https://conductscience.org/api/trials/v1/NCT01916941

GET https://conductscience.org/api/trials/v1/NCT01916941/registered