Trial · NCT01924442

ROOBY Trial Follow-up Extension

NCT01924442, Completed, VA Office of Research and Development; results first posted 2019-06-07

3 sourcestrials-2026-11-12-0.5.0

Cite this record

ConductScience Library. ROOBY Trial Follow-up Extension. Trials, record NCT01924442. Release trials-2026-11-12-0.5.0, 12 Nov 2026. https://conductscience.org/library/trials/NCT01924442

On this page

Trial

As registered on ClinicalTrials.gov, in the graph's capture of the registry.

Title: ROOBY Trial Follow-up Extension
NCT number: NCT01924442
Status: Completed
Enrollment: 2,203 participants, actual
Lead sponsor: VA Office of Research and Development
Conditions: All Cause Mortality, MACE
First posted: 2013-08-16
Last updated: 2019-06-07
Results first posted: 2019-06-07

Source ClinicalTrials.gov

Registered outcomes2

Each outcome the trial registered, primary first, in ClinicalTrials.gov's words.

List	Outcome	Time frame	Description
Primary	Long-term All Cause Mortality Between On-pump and Off-pump Patients.	5 Years	Five-year mortality was initially assessed by matching the participants in the follow-up study to data in the VA Vital Status File and the National Death Index, which provided cause-of-death codes according to the International Classification of Diseases, 10th Revision.
Secondary	Long-term Major Adverse Cardiovascular Event (MACE) Between On-pump and Off-pump Patients	5 years	Secondary outcomes included the 5-year rates of death from cardiac causes, repeat revascularization and nonfatal myocardial infarction.

Source ClinicalTrials.gov

Outcomes2

Each outcome the trial posted results for, in ClinicalTrials.gov's words.

Type	Outcome	Time frame	Population	Units	Measured as
PRIMARY	Long-term All Cause Mortality Between On-pump and Off-pump Patients.	5 Years		Participants	COUNT_OF_PARTICIPANTS
SECONDARY	Long-term Major Adverse Cardiovascular Event (MACE) Between On-pump and Off-pump Patients	5 years		Participants	COUNT_OF_PARTICIPANTS

Source ClinicalTrials.gov

Results by group18

Each measurement the trial posted, group by group, in the words and numbers it posted.

Outcome	Group	Category	Value	Units
Long-term All Cause Mortality Between On-pump and Off-pump Patients.	On-Pump	All cause death	131	Participants
Long-term All Cause Mortality Between On-pump and Off-pump Patients.	Off-Pump	All cause death	168	Participants
Long-term All Cause Mortality Between On-pump and Off-pump Patients.	On-Pump	Composite MACE outcome with death	298	Participants
Long-term All Cause Mortality Between On-pump and Off-pump Patients.	Off-Pump	Composite MACE outcome with death	342	Participants
Long-term All Cause Mortality Between On-pump and Off-pump Patients.	On-Pump	No MACE outcome	670	Participants
Long-term All Cause Mortality Between On-pump and Off-pump Patients.	Off-Pump	No MACE outcome	594	Participants
Long-term Major Adverse Cardiovascular Event (MACE) Between On-pump and Off-pump Patients	On-Pump	Death from cardiac causes	58	Participants
Long-term Major Adverse Cardiovascular Event (MACE) Between On-pump and Off-pump Patients	Off-Pump	Death from cardiac causes	70	Participants
Long-term Major Adverse Cardiovascular Event (MACE) Between On-pump and Off-pump Patients	On-Pump	Acute myocardial infarction	105	Participants
Long-term Major Adverse Cardiovascular Event (MACE) Between On-pump and Off-pump Patients	Off-Pump	Acute myocardial infarction	134	Participants

1 to 10 of 18Source ClinicalTrials.gov

See all 18 results by group

Participant flow6

How many started, completed or left each group, period by period.

Period	Milestone	Group	Participants
Overall Study	STARTED	On-Pump	1,099
Overall Study	STARTED	Off-Pump	1,104
Overall Study	COMPLETED	On-Pump	1,059
Overall Study	COMPLETED	Off-Pump	967
Overall Study	NOT COMPLETED	On-Pump	40
Overall Study	NOT COMPLETED	Off-Pump	137

Source ClinicalTrials.gov

Adverse events10

Each adverse event the trial posted, group by group: the participants affected out of those at risk.

Type	Event	Organ system	Group	Affected	At risk	Events
serious	Death from cardiac causes	Cardiac disorders	On-Pump	58	1,099	58
serious	Death from cardiac causes	Cardiac disorders	Off-Pump	70	1,104	70
serious	Acute myocardial infarction	Cardiac disorders	On-Pump	105	1,099	105
serious	Acute myocardial infarction	Cardiac disorders	Off-Pump	134	1,104	134
serious	Repeat revascularization procedure	Cardiac disorders	On-Pump	131	1,099	131
serious	Repeat revascularization procedure	Cardiac disorders	Off-Pump	145	1,104	145
serious	Percutaneous coronary intervention	Cardiac disorders	On-Pump	127	1,099	127
serious	Percutaneous coronary intervention	Cardiac disorders	Off-Pump	131	1,104	131
serious	Repeat Coronary artery bypass grafting (CABG)	Cardiac disorders	On-Pump	5	1,099	5
serious	Repeat Coronary artery bypass grafting (CABG)	Cardiac disorders	Off-Pump	16	1,104	16

Source ClinicalTrials.gov

Adverse event totals6

The totals the trial posted for each group.

Total	Group	Affected	At risk
Total, all-cause mortality	On-Pump	131	1,099
Total, all-cause mortality	Off-Pump	168	1,104
Total, other adverse events	On-Pump	0	1,099
Total, other adverse events	Off-Pump	0	1,104
Total, serious adverse events	On-Pump	426	1,099
Total, serious adverse events	Off-Pump	496	1,104

Source ClinicalTrials.gov

Papers2

The papers the trial lists on ClinicalTrials.gov.

PMID	Listed as	Source
28813218	DERIVED	PubMed
35171210	DERIVED	PubMed

Grants0

The grants NIH RePORTER links to the trial, newest funded first: NIH's, and some of AHRQ's, CDC's, FDA's and VA's. Each shows its title, principal investigators, organization and funder in its newest year.

None in this release.

Trial comparisons2

Comparisons of the trial's two groups, calculated by ConductScience from the counts it posted.

Comparison	Source
On-Pump vs Off-Pump: deaths from any cause	Trial comparisons
On-Pump vs Off-Pump: serious adverse events	Trial comparisons

Tests0

The ConductCognition tests this trial's registered outcomes name, as ScienceGraph matched them in trial-tests-2026-11-12-0.2.1.

None in this release.

Data dates

The day each source was copied for this release.

ClinicalTrials.gov: 2026-11-12; ClinicalTrials.gov
Results, from AACT: 2026-03-23; AACT
NIH grant links: 2026-11-13; NIH RePORTER

Sources 3

ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
ClinicalTrials.govNo license stated
NIH RePORTER's clinical studies and project filesPublic domain

Each source's terms

ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
ClinicalTrials.govnone stated
NIH RePORTER's clinical studies and project filesPublic domain (NIH RePORTER)

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

For software

Read this trial from software.

The record and each of its lists are JSON, twenty rows a page. No key.

GET https://conductscience.org/api/trials/v1/NCT01924442

GET https://conductscience.org/api/trials/v1/NCT01924442/registered

API reference For AI assistants