Trial · NCT01926236
Active Symptom Control Alone or With mFOLFOX Chemotherapy for Locally Advanced/ Metastatic Biliary Tract Cancers
NCT01926236, Phase 3, Completed, The Christie NHS Foundation Trust
3 sourcestrials-2026-11-12-0.5.0
Cite this record
ConductScience Library. Active Symptom Control Alone or With mFOLFOX Chemotherapy for Locally Advanced/ Metastatic Biliary Tract Cancers. Trials, record NCT01926236. Release trials-2026-11-12-0.5.0, 12 Nov 2026. https://conductscience.org/library/trials/NCT01926236
On this page
Trial
As registered on ClinicalTrials.gov, in the graph's capture of the registry.
- Title
- Active Symptom Control Alone or With mFOLFOX Chemotherapy for Locally Advanced/ Metastatic Biliary Tract Cancers
- NCT number
- NCT01926236
- Status
- Completed
- Phases
- Phase 3
- Enrollment
- 162 participants, actual
- Lead sponsor
- The Christie NHS Foundation Trust
- Conditions
- Biliary Tract Cancer, Gallbladder Cancer, Cholangiocarcinoma, Ampullary Cancer
- Interventions
- Active Symptom Control, L-folinic acid, 5 FU, Oxaliplatin
- First posted
- 2013-08-20
- Last updated
- 2020-01-28
- Other registries' IDs
- eudract:2013-001812-30
Source ClinicalTrials.gov
Registered outcomes8
Each outcome the trial registered, primary first, in ClinicalTrials.gov's words.
| List | Outcome | Time frame | Description |
|---|---|---|---|
| Primary | Overall survival | Evaluated by monthly follow-up until 12 months after last patient included | |
| Secondary | Progression-free survival | Evaluated by monthly follow-up until 12 months after last patient included | Clinical progression assessed monthly, radiological progression assessed to RECIST criteria every 12 weeks for patients in the chemotherapy arm. |
| Secondary | Response rate (chemotherapy arm only) | After 12 weeks of treatment | |
| Secondary | Toxicity (frequency of adverse events and serious adverse events) | Evaluated monthly until 12 months after last patient included | Events will be classified according to CTCAE V4.03 |
| Secondary | Quality of life | Evaluated every 3 months until 12 months after last patient included | Assessed from patient completed questionnaire data: QLQ-C30 and QoL BiL |
| Secondary | Costs of health and social care | Evaluated every 3 months until 12 months after last patient included | |
| Secondary | Health status (Euroqol) | Evaluated every 3 months until 12 months after last patient included | |
| Secondary | Quality adjusted life years (QALYs) | Evaluated every 3 months until 12 months after last patient included | Estimated from Euroqol and survival using published utility tariffs |
Source ClinicalTrials.gov
Outcomes0
Each outcome the trial posted results for, in ClinicalTrials.gov's words.
None in this release.
Results by group0
Each measurement the trial posted, group by group, in the words and numbers it posted.
None in this release.
Participant flow0
How many started, completed or left each group, period by period.
None in this release.
Adverse events0
Each adverse event the trial posted, group by group: the participants affected out of those at risk.
None in this release.
Adverse event totals0
The totals the trial posted for each group.
None in this release.
Papers1
The papers the trial lists on ClinicalTrials.gov.
| PMID | Listed as |
|---|---|
| 33798493 | DERIVED |
Source PubMed
Grants0
The grants NIH RePORTER links to the trial, newest funded first: NIH's, and some of AHRQ's, CDC's, FDA's and VA's. Each shows its title, principal investigators, organization and funder in its newest year.
None in this release.
Trial comparisons0
Comparisons of the trial's two groups, calculated by ConductScience from the counts it posted.
None in this release.
Tests0
The ConductCognition tests this trial's registered outcomes name, as ScienceGraph matched them in trial-tests-2026-11-12-0.2.1.
None in this release.
Data dates
The day each source was copied for this release.
Sources 3
- ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
- ClinicalTrials.govNo license stated
- NIH RePORTER's clinical studies and project filesPublic domain
Each source's terms
- ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
- ClinicalTrials.govnone stated
- NIH RePORTER's clinical studies and project filesPublic domain (NIH RePORTER)
ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.
For software
Read this trial from software.
The record and each of its lists are JSON, twenty rows a page. No key.
GET https://conductscience.org/api/trials/v1/NCT01926236
GET https://conductscience.org/api/trials/v1/NCT01926236/registered