Trial · NCT01928082
The Effects of Estrogen Replacement Therapy in Postmenopausal Women With Hypercalciuria and Low Bone Mass
NCT01928082, Phase 2, Terminated, University of Chicago; results first posted 2018-03-07
3 sourcestrials-2026-11-12-0.5.0
Cite this record
ConductScience Library. The Effects of Estrogen Replacement Therapy in Postmenopausal Women With Hypercalciuria and Low Bone Mass. Trials, record NCT01928082. Release trials-2026-11-12-0.5.0, 12 Nov 2026. https://conductscience.org/library/trials/NCT01928082
On this page
Trial
As registered on ClinicalTrials.gov, in the graph's capture of the registry.
- Title
- The Effects of Estrogen Replacement Therapy in Postmenopausal Women With Hypercalciuria and Low Bone Mass
- NCT number
- NCT01928082
- Status
- Terminated
- Phases
- Phase 2
- Enrollment
- 1 participants, actual
- Lead sponsor
- University of Chicago
- Conditions
- Hypercalciuria, Hypercalciuria, Familial Idiopathic, Osteopenia, Osteoporosis
- Interventions
- Transdermal estradiol
- First posted
- 2013-08-23
- Last updated
- 2018-12-10
- Results first posted
- 2018-03-07
- Limitations and caveats
- Early termination leading to 0 subjects analyzed
Source ClinicalTrials.gov
Registered outcomes15
Each outcome the trial registered, primary first, in ClinicalTrials.gov's words.
| List | Outcome | Time frame | Description |
|---|---|---|---|
| Primary | Absolute Change in 24 Hour Urinary Calcium Excretion | 4 weeks, 8 weeks | 0 participants were measured because the study was terminated |
| Secondary | Serum 1,25-dihydroxyvitamin D3 | 4 weeks, 8 weeks | 0 participants were analyzed because the study was terminated |
| Secondary | Serum Bone Morphogenetic Protein 2 | 4 weeks, 8 weeks | Not available because the study was terminated |
| Secondary | Serum Sclerostin | 4 weeks, 8 weeks | Not available because the study was terminated |
| Other | Serum Estradiol | 4 weeks, 8 weeks | Not available because the study was terminated |
| Other | Serum Total Calcium | 4 weeks, 8 weeks | Not available because the study was terminated |
| Other | Calculated Serum Ionized Calcium | 4 weeks, 8 weeks | Not available because the study was terminated |
| Other | Calculated Tubular Resorption of Calcium | 4 weeks, 8 weeks | Not available because the study was terminated |
| Other | Serum 25 Hydroxyvitamin D | 4 weeks, 8 weeks | Not available because the study was terminated |
| Other | Serum Parathyroid Hormone | 4 weeks, 8 weeks | Not available because the study was terminated |
1 to 10 of 15Source ClinicalTrials.gov
See all 15 registered outcomesOutcomes15
Each outcome the trial posted results for, in ClinicalTrials.gov's words.
| Type | Outcome | Time frame | Population | Units | Measured as |
|---|---|---|---|---|---|
| PRIMARY | Absolute Change in 24 Hour Urinary Calcium Excretion | 4 weeks, 8 weeks | 0 participants were analyzed because the study was terminated | ||
| SECONDARY | Serum 1,25-dihydroxyvitamin D3 | 4 weeks, 8 weeks | The study was terminated | ||
| SECONDARY | Serum Bone Morphogenetic Protein 2 | 4 weeks, 8 weeks | the study was terminated | ||
| SECONDARY | Serum Sclerostin | 4 weeks, 8 weeks | Not available because the study was terminated | ||
| OTHER_PRE_SPECIFIED | Serum Estradiol | 4 weeks, 8 weeks | Not available because the study was terminated | ||
| OTHER_PRE_SPECIFIED | Serum Total Calcium | 4 weeks, 8 weeks | Not available because the study was terminated | ||
| OTHER_PRE_SPECIFIED | Calculated Serum Ionized Calcium | 4 weeks, 8 weeks | Not available because the study was terminated | ||
| OTHER_PRE_SPECIFIED | Calculated Tubular Resorption of Calcium | 4 weeks, 8 weeks | Not available because the study was terminated | ||
| OTHER_PRE_SPECIFIED | Serum 25 Hydroxyvitamin D | 4 weeks, 8 weeks | Not available because the study was terminated | ||
| OTHER_PRE_SPECIFIED | Serum Parathyroid Hormone | 4 weeks, 8 weeks | Not available because the study was terminated |
1 to 10 of 15Source ClinicalTrials.gov
See all 15 outcomesResults by group0
Each measurement the trial posted, group by group, in the words and numbers it posted.
None in this release.
Participant flow3
How many started, completed or left each group, period by period.
| Period | Milestone | Group | Participants | Units counted |
|---|---|---|---|---|
| Overall Study | STARTED | Transdermal Estradiol | 1 | |
| Overall Study | COMPLETED | Transdermal Estradiol | 0 | |
| Overall Study | NOT COMPLETED | Transdermal Estradiol | 1 |
Source ClinicalTrials.gov
Adverse events0
Each adverse event the trial posted, group by group: the participants affected out of those at risk.
None in this release.
Adverse event totals3
The totals the trial posted for each group.
| Total | Group | Affected | At risk |
|---|---|---|---|
| Total, all-cause mortality | Transdermal Estradiol | 0 | 0 |
| Total, other adverse events | Transdermal Estradiol | 0 | 0 |
| Total, serious adverse events | Transdermal Estradiol | 0 | 0 |
Source ClinicalTrials.gov
Papers15
The papers the trial lists on ClinicalTrials.gov.
Grants0
The grants NIH RePORTER links to the trial, newest funded first: NIH's, and some of AHRQ's, CDC's, FDA's and VA's. Each shows its title, principal investigators, organization and funder in its newest year.
None in this release.
Trial comparisons0
Comparisons of the trial's two groups, calculated by ConductScience from the counts it posted.
None in this release.
Tests0
The ConductCognition tests this trial's registered outcomes name, as ScienceGraph matched them in trial-tests-2026-11-12-0.2.1.
None in this release.
Data dates
The day each source was copied for this release.
Sources 3
- ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
- ClinicalTrials.govNo license stated
- NIH RePORTER's clinical studies and project filesPublic domain
Each source's terms
- ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
- ClinicalTrials.govnone stated
- NIH RePORTER's clinical studies and project filesPublic domain (NIH RePORTER)
ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.
For software
Read this trial from software.
The record and each of its lists are JSON, twenty rows a page. No key.
GET https://conductscience.org/api/trials/v1/NCT01928082
GET https://conductscience.org/api/trials/v1/NCT01928082/registered