Trial · NCT01951820
Comparison of Two Topical Anesthetics: Benzocaine Versus Pliaglis
NCT01951820, Phase 4, Completed, University of Michigan; results first posted 2016-07-22
3 sourcestrials-2026-11-12-0.5.0
Cite this record
ConductScience Library. Comparison of Two Topical Anesthetics: Benzocaine Versus Pliaglis. Trials, record NCT01951820. Release trials-2026-11-12-0.5.0, 12 Nov 2026. https://conductscience.org/library/trials/NCT01951820
On this page
Trial
As registered on ClinicalTrials.gov, in the graph's capture of the registry.
- Title
- Comparison of Two Topical Anesthetics: Benzocaine Versus Pliaglis
- NCT number
- NCT01951820
- Status
- Completed
- Phases
- Phase 4
- Enrollment
- 64 participants, actual
- Lead sponsor
- University of Michigan
- Conditions
- Anesthesia of Mucous Membrane
- Interventions
- Pliaglis, Benzocaine, Articaine
- First posted
- 2013-09-27
- Last updated
- 2016-07-22
- Results first posted
- 2016-07-22
Source ClinicalTrials.gov
Registered outcomes1
Each outcome the trial registered, primary first, in ClinicalTrials.gov's words.
| List | Outcome | Time frame | Description |
|---|---|---|---|
| Primary | Measurement of Pain Associated With Injection, in Millimeters, According to Visual Analog Scale | 2.5 minutes | The investigation is trying to determine if the compounded topical anesthetic (Pliaglis) is more effective than the active control (benzocaine) in numbing the gums before needle penetration. The effectiveness of the topical anesthetics will be determined by the patient indicating their level of discomfort felt upon needle stick by using a Heft-Parker visual analog pain scale (scale of 0 - 170mm with 0mm equating to no pain and 170mm equating to maximum pain). |
Source ClinicalTrials.gov
Outcomes1
Each outcome the trial posted results for, in ClinicalTrials.gov's words.
| Type | Outcome | Time frame | Population | Units | Measured as |
|---|---|---|---|---|---|
| PRIMARY | Measurement of Pain Associated With Injection, in Millimeters, According to Visual Analog Scale | 2.5 minutes | mm | MEAN |
Source ClinicalTrials.gov
Results by group2
Each measurement the trial posted, group by group, in the words and numbers it posted.
| Outcome | Group | Category | Value | Spread | Units |
|---|---|---|---|---|---|
| Measurement of Pain Associated With Injection, in Millimeters, According to Visual Analog Scale | Benzocaine | 38.5 | Full Range 0 to 170 | mm | |
| Measurement of Pain Associated With Injection, in Millimeters, According to Visual Analog Scale | Pliaglis | 26.9 | Full Range 0 to 170 | mm |
Source ClinicalTrials.gov
Participant flow6
How many started, completed or left each group, period by period.
| Period | Milestone | Group | Participants | Units counted |
|---|---|---|---|---|
| Overall Study | STARTED | Benzocaine | 34 | |
| Overall Study | STARTED | Pliaglis | 30 | |
| Overall Study | COMPLETED | Benzocaine | 34 | |
| Overall Study | COMPLETED | Pliaglis | 30 | |
| Overall Study | NOT COMPLETED | Benzocaine | 0 | |
| Overall Study | NOT COMPLETED | Pliaglis | 0 |
Source ClinicalTrials.gov
Adverse events0
Each adverse event the trial posted, group by group: the participants affected out of those at risk.
None in this release.
Adverse event totals6
The totals the trial posted for each group.
| Total | Group | Affected | At risk |
|---|---|---|---|
| Total, all-cause mortality | Benzocaine | ||
| Total, all-cause mortality | Pliaglis | ||
| Total, other adverse events | Benzocaine | 0 | 34 |
| Total, other adverse events | Pliaglis | 0 | 30 |
| Total, serious adverse events | Benzocaine | 0 | 34 |
| Total, serious adverse events | Pliaglis | 0 | 30 |
Source ClinicalTrials.gov
Papers0
The papers the trial lists on ClinicalTrials.gov.
None in this release.
Grants0
The grants NIH RePORTER links to the trial, newest funded first: NIH's, and some of AHRQ's, CDC's, FDA's and VA's. Each shows its title, principal investigators, organization and funder in its newest year.
None in this release.
Trial comparisons1
Comparisons of the trial's two groups, calculated by ConductScience from the counts it posted.
| Comparison |
|---|
| Benzocaine vs Pliaglis: serious adverse events |
Source Trial comparisons
Tests0
The ConductCognition tests this trial's registered outcomes name, as ScienceGraph matched them in trial-tests-2026-11-12-0.2.1.
None in this release.
Data dates
The day each source was copied for this release.
Sources 3
- ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
- ClinicalTrials.govNo license stated
- NIH RePORTER's clinical studies and project filesPublic domain
Each source's terms
- ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
- ClinicalTrials.govnone stated
- NIH RePORTER's clinical studies and project filesPublic domain (NIH RePORTER)
ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.
For software
Read this trial from software.
The record and each of its lists are JSON, twenty rows a page. No key.
GET https://conductscience.org/api/trials/v1/NCT01951820
GET https://conductscience.org/api/trials/v1/NCT01951820/registered