Trial · NCT01978535
Iron Sucrose in Adolescents With Iron Deficiency and Postural Orthostatic Tachycardia Syndrome (POTS)
NCT01978535, Phase 1, Phase 2, Terminated, Mayo Clinic; results first posted 2017-11-17
3 sourcestrials-2026-11-12-0.5.0
Cite this record
ConductScience Library. Iron Sucrose in Adolescents With Iron Deficiency and Postural Orthostatic Tachycardia Syndrome (POTS). Trials, record NCT01978535. Release trials-2026-11-12-0.5.0, 12 Nov 2026. https://conductscience.org/library/trials/NCT01978535
On this page
Trial
As registered on ClinicalTrials.gov, in the graph's capture of the registry.
- Title
- Iron Sucrose in Adolescents With Iron Deficiency and Postural Orthostatic Tachycardia Syndrome (POTS)
- NCT number
- NCT01978535
- Status
- Terminated
- Phases
- Phase 1, Phase 2
- Enrollment
- 3 participants, actual
- Lead sponsor
- Mayo Clinic
- Conditions
- Postural Orthostatic Tachycardia Syndrome
- Interventions
- Iron infusion, Normal saline infusion
- First posted
- 2013-11-07
- Last updated
- 2017-11-17
- Results first posted
- 2017-11-17
- Limitations and caveats
- The study was terminated early due to difficulty in recruiting subjects.
Source ClinicalTrials.gov
Registered outcomes1
Each outcome the trial registered, primary first, in ClinicalTrials.gov's words.
| List | Outcome | Time frame | Description |
|---|---|---|---|
| Primary | Cardiovascular Indices-interval Change in Heart Rate During 10-minute Head up Tilt Table Test | 7 (+/- 2) days following intervention | This study will assess whether a single infusion of iron sucrose will improve cardiovascular indices, specifically a reduction in the interval of measured heart rate change, during a ten minute head up tilt, in adolescent subjects with POTS and non-anemic iron deficiency |
Source ClinicalTrials.gov
Outcomes1
Each outcome the trial posted results for, in ClinicalTrials.gov's words.
| Type | Outcome | Time frame | Population | Units | Measured as |
|---|---|---|---|---|---|
| PRIMARY | Cardiovascular Indices-interval Change in Heart Rate During 10-minute Head up Tilt Table Test | 7 (+/- 2) days following intervention | The outcome measure was not analyzed because there were insufficient data. |
Source ClinicalTrials.gov
Results by group0
Each measurement the trial posted, group by group, in the words and numbers it posted.
None in this release.
Participant flow6
How many started, completed or left each group, period by period.
| Period | Milestone | Group | Participants | Units counted |
|---|---|---|---|---|
| Overall Study | STARTED | Iron Infusion | 1 | |
| Overall Study | STARTED | Normal Saline Infusion | 2 | |
| Overall Study | COMPLETED | Iron Infusion | 1 | |
| Overall Study | COMPLETED | Normal Saline Infusion | 2 | |
| Overall Study | NOT COMPLETED | Iron Infusion | 0 | |
| Overall Study | NOT COMPLETED | Normal Saline Infusion | 0 |
Source ClinicalTrials.gov
Adverse events0
Each adverse event the trial posted, group by group: the participants affected out of those at risk.
None in this release.
Adverse event totals6
The totals the trial posted for each group.
| Total | Group | Affected | At risk |
|---|---|---|---|
| Total, all-cause mortality | Iron Infusion | 0 | 1 |
| Total, all-cause mortality | Normal Saline Infusion | 0 | 2 |
| Total, other adverse events | Iron Infusion | 0 | 1 |
| Total, other adverse events | Normal Saline Infusion | 0 | 2 |
| Total, serious adverse events | Iron Infusion | 0 | 1 |
| Total, serious adverse events | Normal Saline Infusion | 0 | 2 |
Source ClinicalTrials.gov
Papers0
The papers the trial lists on ClinicalTrials.gov.
None in this release.
Grants0
The grants NIH RePORTER links to the trial, newest funded first: NIH's, and some of AHRQ's, CDC's, FDA's and VA's. Each shows its title, principal investigators, organization and funder in its newest year.
None in this release.
Trial comparisons2
Comparisons of the trial's two groups, calculated by ConductScience from the counts it posted.
| Comparison | Source |
|---|---|
| Iron Infusion vs Normal Saline Infusion: deaths from any cause | Trial comparisons |
| Iron Infusion vs Normal Saline Infusion: serious adverse events | Trial comparisons |
Tests0
The ConductCognition tests this trial's registered outcomes name, as ScienceGraph matched them in trial-tests-2026-11-12-0.2.1.
None in this release.
Data dates
The day each source was copied for this release.
Sources 3
- ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
- ClinicalTrials.govNo license stated
- NIH RePORTER's clinical studies and project filesPublic domain
Each source's terms
- ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
- ClinicalTrials.govnone stated
- NIH RePORTER's clinical studies and project filesPublic domain (NIH RePORTER)
ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.
For software
Read this trial from software.
The record and each of its lists are JSON, twenty rows a page. No key.
GET https://conductscience.org/api/trials/v1/NCT01978535
GET https://conductscience.org/api/trials/v1/NCT01978535/registered