Trial · NCT01987297
Combined Retinoic Acid,Arsenic Trioxide and Chemo for Newly-diagnosed APL
NCT01987297, Phase 4, Unknown, Shanghai Jiao Tong University School of Medicine
3 sourcestrials-2026-11-12-0.4.0
Cite this record
ConductScience Library. Combined Retinoic Acid,Arsenic Trioxide and Chemo for Newly-diagnosed APL. Trials, record NCT01987297. Release trials-2026-11-12-0.4.0, 12 Nov 2026. https://conductscience.org/library/trials/NCT01987297
On this page
Trial
As registered on ClinicalTrials.gov, in the graph's capture of the registry.
- Title
- Combined Retinoic Acid,Arsenic Trioxide and Chemo for Newly-diagnosed APL
- NCT number
- NCT01987297
- Status
- Unknown
- Phases
- Phase 4
- Enrollment
- 738 participants, estimated
- Lead sponsor
- Shanghai Jiao Tong University School of Medicine
- Conditions
- Acute Promyelocytic Leukemia
- Interventions
- ATRA+Arsenic, ATRA+Chemo
- First posted
- 2013-11-19
- Last updated
- 2019-08-19
Source ClinicalTrials.gov
Registered outcomes7
Each outcome the trial registered, primary first, in ClinicalTrials.gov's words.
| List | Outcome | Time frame | Description |
|---|---|---|---|
| Primary | Disease free survival (DFS) | 3 year | DFS is defined for patients having achieve CR as time to relapse either in bone marrow or extra medullary site, or fail to achieve molecular remission, or death of all causes. |
| Secondary | Complete remission (CR) rate | after induction therapy | Blast and promyelocytic leukemia less than 5% in bone marrow |
| Secondary | Molecular CR (mCR) | after consolidation therapy | mCR is defined the absence of detectable PML-RARα transcripts by nested RT-PCR or RQ-PCR in two successive bone marrow samples |
| Secondary | Early death (ED) rate | 30 days | Early death is referred to death within 30 days from the entry into the treatment. |
| Secondary | Overall survival (OS) | 3 years | OS is defined for patients entering the study as time to death of all causes. |
| Secondary | Cumulated incidence of relapse (CIR) | 3 years | CIR is defined for patients having achieved CR as time to any relapse or persistence of PCR positivity after consolidation therapy |
| Other | Hematological or non hematological toxicitytoxicitie | 3 years | Assessed according to the Common Terminology Criteria for Adverse Events Version 4.0 (National Cancer Institute) |
Source ClinicalTrials.gov
Outcomes0
Each outcome the trial posted results for, in ClinicalTrials.gov's words.
None in this release.
Results by group0
Each measurement the trial posted, group by group, in the words and numbers it posted.
None in this release.
Participant flow0
How many started, completed or left each group, period by period.
None in this release.
Adverse events0
Each adverse event the trial posted, group by group: the participants affected out of those at risk.
None in this release.
Adverse event totals0
The totals the trial posted for each group.
None in this release.
Papers1
The papers the trial lists on ClinicalTrials.gov.
| PMID | Listed as |
|---|---|
| 33495363 | DERIVED |
Source PubMed
Grants0
The grants NIH RePORTER links to the trial, newest funded first: NIH's, and some of AHRQ's, CDC's, FDA's and VA's. Each shows its title, principal investigators, organization and funder in its newest year.
None in this release.
Trial comparisons0
Comparisons of the trial's two groups, calculated by ConductScience from the counts it posted.
None in this release.
Tests0
The ConductCognition tests this trial's registered outcomes name, as ScienceGraph matched them in trial-tests-2026-11-12-0.2.1.
None in this release.
Data dates
The day each source was copied for this release.
Sources 3
- ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
- ClinicalTrials.govNo license stated
- NIH RePORTER's clinical studies and project filesPublic domain
Each source's terms
- ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
- ClinicalTrials.govnone stated
- NIH RePORTER's clinical studies and project filesPublic domain (NIH RePORTER)
ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.
For software
Read this trial from software.
The record and each of its lists are JSON, twenty rows a page. No key.
GET https://conductscience.org/api/trials/v1/NCT01987297
GET https://conductscience.org/api/trials/v1/NCT01987297/registered