Trial · NCT02011516
Baclofen Effects on Marijuana Dependence
NCT02011516, Phase 2, Completed, University of Pennsylvania; results first posted 2017-06-14
3 sourcestrials-2026-11-12-0.5.0
Cite this record
ConductScience Library. Baclofen Effects on Marijuana Dependence. Trials, record NCT02011516. Release trials-2026-11-12-0.5.0, 12 Nov 2026. https://conductscience.org/library/trials/NCT02011516
On this page
Trial
As registered on ClinicalTrials.gov, in the graph's capture of the registry.
- Title
- Baclofen Effects on Marijuana Dependence
- NCT number
- NCT02011516
- Status
- Completed
- Phases
- Phase 2
- Enrollment
- 47 participants, actual
- Lead sponsor
- University of Pennsylvania
- Conditions
- Marijuana Dependence
- Interventions
- Baclofen, Psychosocial, Placebo
- First posted
- 2013-12-13
- Last updated
- 2017-06-14
- Results first posted
- 2017-06-14
- Limitations and caveats
- Sample size too sample to draw conclusions. No subject was able to provide a negative cannabis urine throughout treatment. A caveat is that cannabis stays in the urine for 6 weeks after final use.
Source ClinicalTrials.gov
Registered outcomes1
Each outcome the trial registered, primary first, in ClinicalTrials.gov's words.
| List | Outcome | Time frame | Description |
|---|---|---|---|
| Primary | Urine Drug Screen | study weeks 1-12 | Change from positive to negative over the 12 weeks of a medication regimen |
Source ClinicalTrials.gov
Outcomes1
Each outcome the trial posted results for, in ClinicalTrials.gov's words.
| Type | Outcome | Time frame | Population | Units | Measured as |
|---|---|---|---|---|---|
| PRIMARY | Urine Drug Screen | study weeks 1-12 | Participants | COUNT_OF_PARTICIPANTS |
Source ClinicalTrials.gov
Results by group2
Each measurement the trial posted, group by group, in the words and numbers it posted.
| Outcome | Group | Category | Value | Spread | Units |
|---|---|---|---|---|---|
| Urine Drug Screen | Sugar Pill, Psychosocial Intervention | 0 | Participants | ||
| Urine Drug Screen | Baclofen, Psychosocial Intervention | 0 | Participants |
Source ClinicalTrials.gov
Participant flow6
How many started, completed or left each group, period by period.
| Period | Milestone | Group | Participants | Units counted |
|---|---|---|---|---|
| Overall Study | STARTED | Sugar Pill, Psychosocial Intervention | 8 | |
| Overall Study | STARTED | Baclofen, Psychosocial Intervention | 8 | |
| Overall Study | COMPLETED | Sugar Pill, Psychosocial Intervention | 4 | |
| Overall Study | COMPLETED | Baclofen, Psychosocial Intervention | 6 | |
| Overall Study | NOT COMPLETED | Sugar Pill, Psychosocial Intervention | 4 | |
| Overall Study | NOT COMPLETED | Baclofen, Psychosocial Intervention | 2 |
Source ClinicalTrials.gov
Adverse events26
Each adverse event the trial posted, group by group: the participants affected out of those at risk.
| Type | Event | Organ system | Group | Affected | At risk | Events |
|---|---|---|---|---|---|---|
| other | Headache | General disorders | Sugar Pill, Psychosocial Intervention | 3 | 8 | |
| other | Headache | General disorders | Baclofen, Psychosocial Intervention | 0 | 8 | |
| other | Drowsy/Sluggish | Nervous system disorders | Sugar Pill, Psychosocial Intervention | 3 | 8 | |
| other | Drowsy/Sluggish | Nervous system disorders | Baclofen, Psychosocial Intervention | 1 | 8 | |
| other | Constipation | Gastrointestinal disorders | Sugar Pill, Psychosocial Intervention | 1 | 8 | |
| other | Constipation | Gastrointestinal disorders | Baclofen, Psychosocial Intervention | 0 | 8 | |
| other | Diarrhea | Gastrointestinal disorders | Sugar Pill, Psychosocial Intervention | 1 | 8 | |
| other | Diarrhea | Gastrointestinal disorders | Baclofen, Psychosocial Intervention | 0 | 8 | |
| other | Flatulence | Gastrointestinal disorders | Sugar Pill, Psychosocial Intervention | 1 | 8 | |
| other | Flatulence | Gastrointestinal disorders | Baclofen, Psychosocial Intervention | 0 | 8 |
1 to 10 of 26Source ClinicalTrials.gov
See all 26 adverse eventsAdverse event totals6
The totals the trial posted for each group.
| Total | Group | Affected | At risk |
|---|---|---|---|
| Total, all-cause mortality | Sugar Pill, Psychosocial Intervention | 0 | 8 |
| Total, all-cause mortality | Baclofen, Psychosocial Intervention | 0 | 8 |
| Total, other adverse events | Sugar Pill, Psychosocial Intervention | 4 | 8 |
| Total, other adverse events | Baclofen, Psychosocial Intervention | 4 | 8 |
| Total, serious adverse events | Sugar Pill, Psychosocial Intervention | 0 | 8 |
| Total, serious adverse events | Baclofen, Psychosocial Intervention | 0 | 8 |
Source ClinicalTrials.gov
Papers0
The papers the trial lists on ClinicalTrials.gov.
None in this release.
Grants0
The grants NIH RePORTER links to the trial, newest funded first: NIH's, and some of AHRQ's, CDC's, FDA's and VA's. Each shows its title, principal investigators, organization and funder in its newest year.
None in this release.
Trial comparisons3
Comparisons of the trial's two groups, calculated by ConductScience from the counts it posted.
| Comparison | Source |
|---|---|
| Sugar Pill, Psychosocial Intervention vs Baclofen, Psychosocial Intervention: Urine Drug Screen | Trial comparisons |
| Sugar Pill, Psychosocial Intervention vs Baclofen, Psychosocial Intervention: deaths from any cause | Trial comparisons |
| Sugar Pill, Psychosocial Intervention vs Baclofen, Psychosocial Intervention: serious adverse events | Trial comparisons |
Tests0
The ConductCognition tests this trial's registered outcomes name, as ScienceGraph matched them in trial-tests-2026-11-12-0.2.1.
None in this release.
Data dates
The day each source was copied for this release.
Sources 3
- ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
- ClinicalTrials.govNo license stated
- NIH RePORTER's clinical studies and project filesPublic domain
Each source's terms
- ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
- ClinicalTrials.govnone stated
- NIH RePORTER's clinical studies and project filesPublic domain (NIH RePORTER)
ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.
For software
Read this trial from software.
The record and each of its lists are JSON, twenty rows a page. No key.
GET https://conductscience.org/api/trials/v1/NCT02011516
GET https://conductscience.org/api/trials/v1/NCT02011516/events?page=2