Trial · NCT02021110
Ursodeoxycholic Acid as Treatment for Polycystic Liver Disease
NCT02021110, Phase 2, Completed, Radboud University Medical Center
3 sourcestrials-2026-11-12-0.5.0
Cite this record
ConductScience Library. Ursodeoxycholic Acid as Treatment for Polycystic Liver Disease. Trials, record NCT02021110. Release trials-2026-11-12-0.5.0, 12 Nov 2026. https://conductscience.org/library/trials/NCT02021110
On this page
Trial
As registered on ClinicalTrials.gov, in the graph's capture of the registry.
- Title
- Ursodeoxycholic Acid as Treatment for Polycystic Liver Disease
- NCT number
- NCT02021110
- Status
- Completed
- Phases
- Phase 2
- Enrollment
- 34 participants, actual
- Lead sponsor
- Radboud University Medical Center
- Conditions
- Polycystic Liver Disease, Polycystic Kidney, Autosomal Dominant
- Interventions
- Ursodeoxycholic Acid
- First posted
- 2013-12-27
- Last updated
- 2021-09-23
Source ClinicalTrials.gov
Registered outcomes7
Each outcome the trial registered, primary first, in ClinicalTrials.gov's words.
| List | Outcome | Time frame | Description |
|---|---|---|---|
| Primary | Effect of UDCA on total liver volume | Baseline to week 24 | Proportional change of total liver volume in UDCA treated patients versus non treated patients, as assessed by CT at baseline and week 24 |
| Secondary | Effect of UDCA-therapy on absolute total liver volume | Baseline to week 24 | Absolute total liver volume at baseline and end of treatment (week 24) will be measured |
| Secondary | Effect of UDCA on gastro-intestinal symptoms measured by a GI-questionnaire | Baseline to week 24 | Improvement in Gastrointestinal Symptom score |
| Secondary | Effect of UDCA on health related quality of life as measured by Study Form -36 | Baseline to week 24 | Improvement in Study Form -36 score |
| Secondary | Proportion of patients with any reduction in total liver volume after 24 weeks | Baseline to week 24 | Proportion reduction in total liver volume |
| Secondary | Effect of UDCA on absolute total kidney volume | Baseline to week 24 | Change in total kidney volume after 24 weeks |
| Other | Adverse events as a measure of tolerability and safety of UDCA | Baseline to week 24 | All adverse events |
Source ClinicalTrials.gov
Outcomes0
Each outcome the trial posted results for, in ClinicalTrials.gov's words.
None in this release.
Results by group0
Each measurement the trial posted, group by group, in the words and numbers it posted.
None in this release.
Participant flow0
How many started, completed or left each group, period by period.
None in this release.
Adverse events0
Each adverse event the trial posted, group by group: the participants affected out of those at risk.
None in this release.
Adverse event totals0
The totals the trial posted for each group.
None in this release.
Papers1
The papers the trial lists on ClinicalTrials.gov.
| PMID | Listed as |
|---|---|
| 27212247 | DERIVED |
Source PubMed
Grants0
The grants NIH RePORTER links to the trial, newest funded first: NIH's, and some of AHRQ's, CDC's, FDA's and VA's. Each shows its title, principal investigators, organization and funder in its newest year.
None in this release.
Trial comparisons0
Comparisons of the trial's two groups, calculated by ConductScience from the counts it posted.
None in this release.
Tests0
The ConductCognition tests this trial's registered outcomes name, as ScienceGraph matched them in trial-tests-2026-11-12-0.2.1.
None in this release.
Data dates
The day each source was copied for this release.
Sources 3
- ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
- ClinicalTrials.govNo license stated
- NIH RePORTER's clinical studies and project filesPublic domain
Each source's terms
- ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
- ClinicalTrials.govnone stated
- NIH RePORTER's clinical studies and project filesPublic domain (NIH RePORTER)
ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.
For software
Read this trial from software.
The record and each of its lists are JSON, twenty rows a page. No key.
GET https://conductscience.org/api/trials/v1/NCT02021110
GET https://conductscience.org/api/trials/v1/NCT02021110/registered