Trial · NCT02025608
Autonomic Function and Cardiovascular Risk in Restless Legs Syndrome
NCT02025608, Phase 4, Completed, Mauro Manconi
3 sourcestrials-2026-11-12-0.5.0
Cite this record
ConductScience Library. Autonomic Function and Cardiovascular Risk in Restless Legs Syndrome. Trials, record NCT02025608. Release trials-2026-11-12-0.5.0, 12 Nov 2026. https://conductscience.org/library/trials/NCT02025608
On this page
Trial
As registered on ClinicalTrials.gov, in the graph's capture of the registry.
- Title
- Autonomic Function and Cardiovascular Risk in Restless Legs Syndrome
- NCT number
- NCT02025608
- Status
- Completed
- Phases
- Phase 4
- Enrollment
- 20 participants, actual
- Lead sponsor
- Mauro Manconi
- Conditions
- Restless Legs Syndrome
- Interventions
- Pramipexole, Placebo
- First posted
- 2014-01-01
- Last updated
- 2017-01-24
Source ClinicalTrials.gov
Registered outcomes4
Each outcome the trial registered, primary first, in ClinicalTrials.gov's words.
| List | Outcome | Time frame | Description |
|---|---|---|---|
| Primary | Change in heart rate activations during sleep from baseline to 4 weeks | Baseline, Week 4 | Number and amplitude of periodic leg movements during sleep (PLMS) and non-PLMS related heart rate activations during stable nocturnal sleep |
| Secondary | Change in baroreflex from baseline to 4 weeks | Baseline, Week 4 | Baroreflex sensitivity and baroreflex gain derived from tilt table tes |
| Secondary | Change in blood serum markers from baseline to 4 weeks | Baseline, Week 4 | Highly-sensitive C reactive protein (hsCRP), lipoprotein-associated phospholipase A2 (lP-PLA2), and oxidised low density lipoprotein (oxLDL) |
| Other | Change in chemoreflexes from baseline to 4 weeks | Baseline, Week 4 | Peripheral and central chemoreflex sensitivity derived from carbon dioxide (CO2) rebreathing test |
Source ClinicalTrials.gov
Outcomes0
Each outcome the trial posted results for, in ClinicalTrials.gov's words.
None in this release.
Results by group0
Each measurement the trial posted, group by group, in the words and numbers it posted.
None in this release.
Participant flow0
How many started, completed or left each group, period by period.
None in this release.
Adverse events0
Each adverse event the trial posted, group by group: the participants affected out of those at risk.
None in this release.
Adverse event totals0
The totals the trial posted for each group.
None in this release.
Papers0
The papers the trial lists on ClinicalTrials.gov.
None in this release.
Grants0
The grants NIH RePORTER links to the trial, newest funded first: NIH's, and some of AHRQ's, CDC's, FDA's and VA's. Each shows its title, principal investigators, organization and funder in its newest year.
None in this release.
Trial comparisons0
Comparisons of the trial's two groups, calculated by ConductScience from the counts it posted.
None in this release.
Tests0
The ConductCognition tests this trial's registered outcomes name, as ScienceGraph matched them in trial-tests-2026-11-12-0.2.1.
None in this release.
Data dates
The day each source was copied for this release.
Sources 3
- ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
- ClinicalTrials.govNo license stated
- NIH RePORTER's clinical studies and project filesPublic domain
Each source's terms
- ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
- ClinicalTrials.govnone stated
- NIH RePORTER's clinical studies and project filesPublic domain (NIH RePORTER)
ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.
For software
Read this trial from software.
The record and each of its lists are JSON, twenty rows a page. No key.
GET https://conductscience.org/api/trials/v1/NCT02025608
GET https://conductscience.org/api/trials/v1/NCT02025608/registered