Trial · NCT02086500

Study of Tranexamic Acid During Air and Ground Medical Prehospital Transport Trial (STAAMP Trial)

NCT02086500, Phase 3, Completed, Jason Sperry; results first posted 2020-09-10

3 sourcestrials-2026-11-12-0.5.0

Cite this record

ConductScience Library. Study of Tranexamic Acid During Air and Ground Medical Prehospital Transport Trial (STAAMP Trial). Trials, record NCT02086500. Release trials-2026-11-12-0.5.0, 12 Nov 2026. https://conductscience.org/library/trials/NCT02086500

On this page

Trial

As registered on ClinicalTrials.gov, in the graph's capture of the registry.

Title: Study of Tranexamic Acid During Air and Ground Medical Prehospital Transport Trial (STAAMP Trial)
NCT number: NCT02086500
Status: Completed
Phases: Phase 3
Enrollment: 903 participants, actual
Lead sponsor: Jason Sperry
Conditions: Traumatic Hemorrhage
Interventions: Tranexamic Acid, Saline control
First posted: 2014-03-13
Last updated: 2020-09-10
Results first posted: 2020-09-10

Source ClinicalTrials.gov

Registered outcomes7

Each outcome the trial registered, primary first, in ClinicalTrials.gov's words.

List	Outcome	Time frame	Description
Primary	30 Day Mortality	30 Day	Because not all patients had available data regarding 30-day mortality (patients were discharged and there 30-day outcome was unable to be determined) there may be differences between the 30Day mortality relative to the other outcomes. There were 5 and 4 patients from each arm that did not have 30-day outcome and thus are different.
Secondary	24 Hour Mortality	24 Hours
Secondary	Acute Lung Injury	7 days
Secondary	Multiple Organ Failure	30 days
Secondary	Nosocomial Infection	30 days
Secondary	24 Hour Total Blood Transfusion	24 hours
Secondary	Hyperfinbrinolysis	24 hours

Source ClinicalTrials.gov

Outcomes7

Each outcome the trial posted results for, in ClinicalTrials.gov's words.

Type	Outcome	Time frame	Population	Units	Measured as
PRIMARY	30 Day Mortality	30 Day	Because not all patients had available data regarding 30-day mortality (patients were discharged and there 30-day outcome was unable to be determined) there may be differences between the 30Day mortality relative to the other outcomes. There were 5 and 4 patients from each arm that did not have 30-day outcome and thus are different.	Participants	COUNT_OF_PARTICIPANTS
SECONDARY	24 Hour Mortality	24 Hours		Participants	COUNT_OF_PARTICIPANTS
SECONDARY	Acute Lung Injury	7 days		Participants	COUNT_OF_PARTICIPANTS
SECONDARY	Multiple Organ Failure	30 days		Participants	COUNT_OF_PARTICIPANTS
SECONDARY	Nosocomial Infection	30 days		Participants	COUNT_OF_PARTICIPANTS
SECONDARY	24 Hour Total Blood Transfusion	24 hours		units of blood transfusion	MEDIAN
SECONDARY	Hyperfinbrinolysis	24 hours		Participants	COUNT_OF_PARTICIPANTS

Source ClinicalTrials.gov

Results by group14

Each measurement the trial posted, group by group, in the words and numbers it posted.

Outcome	Group	Value	Units
30 Day Mortality	Prehospital Tranexamic Acid	36	Participants
30 Day Mortality	Control	45	Participants
24 Hour Mortality	Prehospital Tranexamic Acid	16	Participants
24 Hour Mortality	Control	17	Participants
Acute Lung Injury	Prehospital Tranexamic Acid	42	Participants
Acute Lung Injury	Control	39	Participants
Multiple Organ Failure	Prehospital Tranexamic Acid	33	Participants
Multiple Organ Failure	Control	39	Participants
Nosocomial Infection	Prehospital Tranexamic Acid	88	Participants
Nosocomial Infection	Control	66	Participants

1 to 10 of 14Source ClinicalTrials.gov

See all 14 results by group

Participant flow6

How many started, completed or left each group, period by period.

Period	Milestone	Group	Participants
Overall Study	STARTED	Prehospital Tranexamic Acid	447
Overall Study	STARTED	Control	456
Overall Study	COMPLETED	Prehospital Tranexamic Acid	447
Overall Study	COMPLETED	Control	456
Overall Study	NOT COMPLETED	Prehospital Tranexamic Acid	0
Overall Study	NOT COMPLETED	Control	0

Source ClinicalTrials.gov

Adverse events34

Each adverse event the trial posted, group by group: the participants affected out of those at risk.

Type	Event	Organ system	Group	Affected	At risk	Events
other	ileus	Gastrointestinal disorders	Prehospital Tranexamic Acid	1	447	1
other	ileus	Gastrointestinal disorders	Control	1	456	1
other	Metabolic Acidosis	Metabolism and nutrition disorders	Prehospital Tranexamic Acid	1	447	1
other	Metabolic Acidosis	Metabolism and nutrition disorders	Control	0	456	0
other	Hydrocephalus	Nervous system disorders	Prehospital Tranexamic Acid	0	447	0
other	Hydrocephalus	Nervous system disorders	Control	1	456	1
other	Hypertriglyceridemia	Metabolism and nutrition disorders	Prehospital Tranexamic Acid	0	447	0
other	Hypertriglyceridemia	Metabolism and nutrition disorders	Control	1	456	1
other	Nausea	Gastrointestinal disorders	Prehospital Tranexamic Acid	0	447	0
other	Nausea	Gastrointestinal disorders	Control	1	456	1

1 to 10 of 34Source ClinicalTrials.gov

See all 34 adverse events

Adverse event totals6

The totals the trial posted for each group.

Total	Group	Affected	At risk
Total, all-cause mortality	Prehospital Tranexamic Acid	36	447
Total, all-cause mortality	Control	45	456
Total, other adverse events	Prehospital Tranexamic Acid	4	447
Total, other adverse events	Control	14	456
Total, serious adverse events	Prehospital Tranexamic Acid	4	447
Total, serious adverse events	Control	7	456

Source ClinicalTrials.gov

Papers3

The papers the trial lists on ClinicalTrials.gov.

PMID	Listed as	Source
33016996	DERIVED	PubMed
37125811	DERIVED	PubMed
38933603	DERIVED	PubMed

Grants0

The grants NIH RePORTER links to the trial, newest funded first: NIH's, and some of AHRQ's, CDC's, FDA's and VA's. Each shows its title, principal investigators, organization and funder in its newest year.

None in this release.

Trial comparisons8

Comparisons of the trial's two groups, calculated by ConductScience from the counts it posted.

Comparison	Source
Prehospital Tranexamic Acid vs Control: Multiple Organ Failure	Trial comparisons
Prehospital Tranexamic Acid vs Control: 24 Hour Mortality	Trial comparisons
Prehospital Tranexamic Acid vs Control: Hyperfinbrinolysis	Trial comparisons
Prehospital Tranexamic Acid vs Control: 30 Day Mortality	Trial comparisons
Prehospital Tranexamic Acid vs Control: deaths from any cause	Trial comparisons
Prehospital Tranexamic Acid vs Control: Acute Lung Injury	Trial comparisons
Prehospital Tranexamic Acid vs Control: Nosocomial Infection	Trial comparisons
Prehospital Tranexamic Acid vs Control: serious adverse events	Trial comparisons

Tests0

The ConductCognition tests this trial's registered outcomes name, as ScienceGraph matched them in trial-tests-2026-11-12-0.2.1.

None in this release.

Data dates

The day each source was copied for this release.

ClinicalTrials.gov: 2026-11-12; ClinicalTrials.gov
Results, from AACT: 2026-03-23; AACT
NIH grant links: 2026-11-13; NIH RePORTER

Sources 3

ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
ClinicalTrials.govNo license stated
NIH RePORTER's clinical studies and project filesPublic domain

Each source's terms

ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
ClinicalTrials.govnone stated
NIH RePORTER's clinical studies and project filesPublic domain (NIH RePORTER)

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

For software

Read this trial from software.

The record and each of its lists are JSON, twenty rows a page. No key.

GET https://conductscience.org/api/trials/v1/NCT02086500

GET https://conductscience.org/api/trials/v1/NCT02086500/events?page=2

API reference For AI assistants