Trial · NCT02106104
Renal Effects of DPP-4 Inhibitor Linagliptin in Type 2 Diabetes
NCT02106104, Phase 4, Completed, Amsterdam UMC, location VUmc
3 sourcestrials-2026-11-12-0.5.0
Cite this record
ConductScience Library. Renal Effects of DPP-4 Inhibitor Linagliptin in Type 2 Diabetes. Trials, record NCT02106104. Release trials-2026-11-12-0.5.0, 12 Nov 2026. https://conductscience.org/library/trials/NCT02106104
On this page
Trial
As registered on ClinicalTrials.gov, in the graph's capture of the registry.
- Title
- Renal Effects of DPP-4 Inhibitor Linagliptin in Type 2 Diabetes
- NCT number
- NCT02106104
- Status
- Completed
- Phases
- Phase 4
- Enrollment
- 48 participants, actual
- Lead sponsor
- Amsterdam UMC, location VUmc
- Conditions
- Type 2 Diabetes
- Interventions
- Linagliptin 5 mg QD (N=24), Glimepiride 1 mg QD (N=24)
- First posted
- 2014-04-08
- Last updated
- 2016-05-17
- Other registries' IDs
- eudract:2013-002493-47
Source ClinicalTrials.gov
Registered outcomes13
Each outcome the trial registered, primary first, in ClinicalTrials.gov's words.
| List | Outcome | Time frame | Description |
|---|---|---|---|
| Primary | Changes from baseline following 8-week treatment with linagliptin vs glimepiride on fasting and postprandial renal hemodynamics, measured as GFR / ERPF (determined by inulin/para-aminohippuric-acid clearance) | 8 weeks | |
| Secondary | Renal tubular function | 8 weeks | |
| Secondary | Renal damage, measured by urine biomarkers | 8 weeks | |
| Secondary | Blood Pressure and Heart Rate | 8 weeks | |
| Other | Body anthropometrics: body weight, height, body mass index, waist circumference | 8 weeks | |
| Other | Body fat content | 8 weeks | |
| Other | Systemic hemodynamic variables (blood pressure, heart rate, stroke volume, cardiac output/-index, total systemic vascular resistance) | 8 weeks | Derived from non-invasive beat-to-beat finger blood pressure measurements |
| Other | Cardiac autonomic nervous system function | 8 weeks | |
| Other | Microvascular function | 8 weeks | |
| Other | Arterial stiffness | 8 weeks |
1 to 10 of 13Source ClinicalTrials.gov
See all 13 registered outcomesOutcomes0
Each outcome the trial posted results for, in ClinicalTrials.gov's words.
None in this release.
Results by group0
Each measurement the trial posted, group by group, in the words and numbers it posted.
None in this release.
Participant flow0
How many started, completed or left each group, period by period.
None in this release.
Adverse events0
Each adverse event the trial posted, group by group: the participants affected out of those at risk.
None in this release.
Adverse event totals0
The totals the trial posted for each group.
None in this release.
Papers2
The papers the trial lists on ClinicalTrials.gov.
Grants0
The grants NIH RePORTER links to the trial, newest funded first: NIH's, and some of AHRQ's, CDC's, FDA's and VA's. Each shows its title, principal investigators, organization and funder in its newest year.
None in this release.
Trial comparisons0
Comparisons of the trial's two groups, calculated by ConductScience from the counts it posted.
None in this release.
Tests0
The ConductCognition tests this trial's registered outcomes name, as ScienceGraph matched them in trial-tests-2026-11-12-0.2.1.
None in this release.
Data dates
The day each source was copied for this release.
Sources 3
- ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
- ClinicalTrials.govNo license stated
- NIH RePORTER's clinical studies and project filesPublic domain
Each source's terms
- ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
- ClinicalTrials.govnone stated
- NIH RePORTER's clinical studies and project filesPublic domain (NIH RePORTER)
ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.
For software
Read this trial from software.
The record and each of its lists are JSON, twenty rows a page. No key.
GET https://conductscience.org/api/trials/v1/NCT02106104
GET https://conductscience.org/api/trials/v1/NCT02106104/registered