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Trial · NCT02121756

Results by group36

Each measurement the trial posted, group by group, in the words and numbers it posted.

OutcomeGroupCategoryValueSpreadUnits
Monocyte and Macrophage Activation Assessed as Change in Plasma Levels of sCD14 From Baseline to Week 12ARM A: Dipyridamole for 24 Weeks244500.00Inter-Quartile Range -318792.00 to 479000.00pg/ml
Monocyte and Macrophage Activation Assessed as Change in Plasma Levels of sCD14 From Baseline to Week 12ARM B: Placebo for 12 Weeks Then Dipyridamole for 12 Weeks-58250.00Inter-Quartile Range -572567.50 to 287500.00pg/ml
Monocyte and Macrophage Activation Assessed as Change in Plasma Levels of sCD163 From Baseline to Week 12ARM A: Dipyridamole for 24 Weeks-6.19Inter-Quartile Range -78.04 to 25.93ng/ml
Monocyte and Macrophage Activation Assessed as Change in Plasma Levels of sCD163 From Baseline to Week 12ARM B: Placebo for 12 Weeks Then Dipyridamole for 12 Weeks5.42Inter-Quartile Range -38.33 to 88.33ng/ml
Systemic Inflammation Assessed as Change in IL-6 Plasma Levels From Baseline to Week 12ARM A: Dipyridamole for 24 Weeks-0.02Inter-Quartile Range -0.36 to 0.86pg/ml
Systemic Inflammation Assessed as Change in IL-6 Plasma Levels From Baseline to Week 12ARM B: Placebo for 12 Weeks Then Dipyridamole for 12 Weeks-0.07Inter-Quartile Range -0.59 to 0.88pg/ml
Immune System Activation as Measured by the Proportion of CD8+ T Cells Co-expressing CD69 and CD25 After 12 Weeks of Dipyridamole Treatment Compared to PlaceboARM A: Dipyridamole for 24 Weeks-0.05Inter-Quartile Range -0.15 to 0.00proportion of CD8+ T cells
Immune System Activation as Measured by the Proportion of CD8+ T Cells Co-expressing CD69 and CD25 After 12 Weeks of Dipyridamole Treatment Compared to PlaceboARM B: Placebo for 12 Weeks Then Dipyridamole for 12 Weeks0.00Inter-Quartile Range -0.05 to 0.05proportion of CD8+ T cells
Safety and Tolerability of Dipyridamole Assessed as the Number of Participants With Grade 2 or Higher Adverse Events or Treatment DiscontinuationsARM A: Dipyridamole for 24 WeeksGrade 2 adverse events12Participants
Safety and Tolerability of Dipyridamole Assessed as the Number of Participants With Grade 2 or Higher Adverse Events or Treatment DiscontinuationsARM B: Placebo for 12 Weeks Then Dipyridamole for 12 WeeksGrade 2 adverse events10Participants
Safety and Tolerability of Dipyridamole Assessed as the Number of Participants With Grade 2 or Higher Adverse Events or Treatment DiscontinuationsARM A: Dipyridamole for 24 WeeksGrade 3 adverse events2Participants
Safety and Tolerability of Dipyridamole Assessed as the Number of Participants With Grade 2 or Higher Adverse Events or Treatment DiscontinuationsARM B: Placebo for 12 Weeks Then Dipyridamole for 12 WeeksGrade 3 adverse events1Participants
Safety and Tolerability of Dipyridamole Assessed as the Number of Participants With Grade 2 or Higher Adverse Events or Treatment DiscontinuationsARM A: Dipyridamole for 24 WeeksTreatment discontinuations4Participants
Safety and Tolerability of Dipyridamole Assessed as the Number of Participants With Grade 2 or Higher Adverse Events or Treatment DiscontinuationsARM B: Placebo for 12 Weeks Then Dipyridamole for 12 WeeksTreatment discontinuations0Participants
Safety and Tolerability of Dipyridamole Assessed as the Number of Participants With Grade 2 or Higher Adverse Events or Treatment DiscontinuationsARM A: Dipyridamole for 24 WeeksNo Grade 2 or 3 AEs or treatment discontinuations3Participants
Safety and Tolerability of Dipyridamole Assessed as the Number of Participants With Grade 2 or Higher Adverse Events or Treatment DiscontinuationsARM B: Placebo for 12 Weeks Then Dipyridamole for 12 WeeksNo Grade 2 or 3 AEs or treatment discontinuations8Participants
Immune System Activation Assessed as the Change in the Proportion of Cycling CD4+ T Cells as Measured by Ki-67 Expression at Baseline and After Treatment With DipyridamoleARM A: Dipyridamole for 24 Weeks-0.15Inter-Quartile Range -0.30 to -0.05proportion of cycling CD4+ T Cells
Immune System Activation Assessed as the Change in the Proportion of Cycling CD4+ T Cells as Measured by Ki-67 Expression at Baseline and After Treatment With DipyridamoleARM B: Placebo for 12 Weeks Then Dipyridamole for 12 Weeks-0.05Inter-Quartile Range -0.20 to 0.05proportion of cycling CD4+ T Cells
Immune System Activation as Measured by the Proportion of CD4+ T Cells Co-expressing HLA-DR and CD38 After 12 Weeks of Dipyridamole Treatment Compared to PlaceboARM A: Dipyridamole for 24 Weeks-0.25Inter-Quartile Range -0.70 to 0.00proportion of CD4+ T cells
Immune System Activation as Measured by the Proportion of CD4+ T Cells Co-expressing HLA-DR and CD38 After 12 Weeks of Dipyridamole Treatment Compared to PlaceboARM B: Placebo for 12 Weeks Then Dipyridamole for 12 Weeks0.10Inter-Quartile Range -0.65 to 0.55proportion of CD4+ T cells

Source ClinicalTrials.govtrials-2026-11-12-0.5.0

Sources 3

  • ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
  • ClinicalTrials.govNo license stated
  • NIH RePORTER's clinical studies and project filesPublic domain
Each source's terms
  • ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
  • ClinicalTrials.govnone stated
  • NIH RePORTER's clinical studies and project filesPublic domain (NIH RePORTER)

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

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