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Study to Investigate Safety, Pharmacokinetic (PK), Pharmacodynamic (PD) and Clinical Activity of Trametinib in Subjects With Cancer or Plexiform Neurofibromas and Trametinib in Combination With Dabrafenib in Subjects With Cancers Harboring V600 Mutations
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Trial · NCT02124772

Adverse events8,138

Each adverse event the trial posted, group by group: the participants affected out of those at risk.

1 to 20 of 8,138

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TypeEventOrgan systemGroupAffectedAt riskEvents
otherAnaemiaBlood and lymphatic system disordersPart A - TMT 0.0125 mg/kg/Day03
otherAnaemiaBlood and lymphatic system disordersPart A - TMT 0.025 mg/kg/Day919
otherAnaemiaBlood and lymphatic system disordersPart A - TMT 0.032 mg/kg/Day612
otherAnaemiaBlood and lymphatic system disordersPart A - TMT 0.04 mg/kg/Day716
otherAnaemiaBlood and lymphatic system disordersPart B - Neuroblastoma611
otherAnaemiaBlood and lymphatic system disordersPart B - LGG Fusion310
otherAnaemiaBlood and lymphatic system disordersPart B - NF-1 With PN410
otherAnaemiaBlood and lymphatic system disordersPart B - BRAF V600 Mutant Solid Tumor510
otherAnaemiaBlood and lymphatic system disordersPart C - TMT 0.025 mg/kg/Day + 50% DRB RP2D03
otherAnaemiaBlood and lymphatic system disordersPart C - TMT 0.025 mg/kg/Day + 100% DRB RP2D49
otherAnaemiaBlood and lymphatic system disordersPart C - TMT 0.032 mg/kg/Day + 100% DRB RP2D16
otherAnaemiaBlood and lymphatic system disordersPart D - LGG420
otherAnaemiaBlood and lymphatic system disordersPart D - LCH210
otherBone marrow oedemaBlood and lymphatic system disordersPart A - TMT 0.0125 mg/kg/Day03
otherBone marrow oedemaBlood and lymphatic system disordersPart A - TMT 0.025 mg/kg/Day019
otherBone marrow oedemaBlood and lymphatic system disordersPart A - TMT 0.032 mg/kg/Day112
otherBone marrow oedemaBlood and lymphatic system disordersPart A - TMT 0.04 mg/kg/Day016
otherBone marrow oedemaBlood and lymphatic system disordersPart B - Neuroblastoma011
otherBone marrow oedemaBlood and lymphatic system disordersPart B - LGG Fusion010
otherBone marrow oedemaBlood and lymphatic system disordersPart B - NF-1 With PN010

Source ClinicalTrials.govtrials-2026-11-12-0.5.0

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Sources 3

  • ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
  • ClinicalTrials.govNo license stated
  • NIH RePORTER's clinical studies and project filesPublic domain
Each source's terms
  • ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
  • ClinicalTrials.govnone stated
  • NIH RePORTER's clinical studies and project filesPublic domain (NIH RePORTER)

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

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GET https://conductscience.org/api/trials/v1/NCT02124772/events

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