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Study to Investigate Safety, Pharmacokinetic (PK), Pharmacodynamic (PD) and Clinical Activity of Trametinib in Subjects With Cancer or Plexiform Neurofibromas and Trametinib in Combination With Dabrafenib in Subjects With Cancers Harboring V600 Mutations
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Trial · NCT02124772

Participant flow39

How many started, completed or left each group, period by period.

1 to 20 of 39

Download this page as JSON
PeriodMilestoneGroupParticipantsUnits counted
Overall StudySTARTEDPart A - TMT 0.0125 mg/kg/Day3
Overall StudySTARTEDPart A - TMT 0.025 mg/kg/Day19
Overall StudySTARTEDPart A - TMT 0.032 mg/kg/Day12
Overall StudySTARTEDPart A - TMT 0.04 mg/kg/Day16
Overall StudySTARTEDPart B - Neuroblastoma11
Overall StudySTARTEDPart B - LGG Fusion10
Overall StudySTARTEDPart B - NF-1 With PN10
Overall StudySTARTEDPart B - BRAF V600 Mutant Solid Tumor10
Overall StudySTARTEDPart C - TMT 0.025 mg/kg/Day + 50% DRB RP2D3
Overall StudySTARTEDPart C - TMT 0.025 mg/kg/Day + 100% DRB RP2D9
Overall StudySTARTEDPart C - TMT 0.032 mg/kg/Day + 100% DRB RP2D6
Overall StudySTARTEDPart D - LGG20
Overall StudySTARTEDPart D - LCH10
Overall StudyCOMPLETEDPart A - TMT 0.0125 mg/kg/Day0
Overall StudyCOMPLETEDPart A - TMT 0.025 mg/kg/Day5
Overall StudyCOMPLETEDPart A - TMT 0.032 mg/kg/Day6
Overall StudyCOMPLETEDPart A - TMT 0.04 mg/kg/Day3
Overall StudyCOMPLETEDPart B - Neuroblastoma2
Overall StudyCOMPLETEDPart B - LGG Fusion2
Overall StudyCOMPLETEDPart B - NF-1 With PN2

Source ClinicalTrials.govtrials-2026-11-12-0.5.0

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Sources 3

  • ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
  • ClinicalTrials.govNo license stated
  • NIH RePORTER's clinical studies and project filesPublic domain
Each source's terms
  • ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
  • ClinicalTrials.govnone stated
  • NIH RePORTER's clinical studies and project filesPublic domain (NIH RePORTER)

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

For software

Read this list from software.

Twenty rows a page, as JSON. No key.

GET https://conductscience.org/api/trials/v1/NCT02124772/flow

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