Trial · NCT02124824
Contribution of Endothelin-1 to Exercise Intolerance in Heart Failure
NCT02124824, Early phase 1, Completed, VA Office of Research and Development; results first posted 2021-12-20
3 sourcestrials-2026-11-12-0.5.0
Cite this record
ConductScience Library. Contribution of Endothelin-1 to Exercise Intolerance in Heart Failure. Trials, record NCT02124824. Release trials-2026-11-12-0.5.0, 12 Nov 2026. https://conductscience.org/library/trials/NCT02124824
On this page
Trial
As registered on ClinicalTrials.gov, in the graph's capture of the registry.
- Title
- Contribution of Endothelin-1 to Exercise Intolerance in Heart Failure
- NCT number
- NCT02124824
- Status
- Completed
- Phases
- Early phase 1
- Enrollment
- 30 participants, actual
- Lead sponsor
- VA Office of Research and Development
- Conditions
- Heart Failure
- Interventions
- BQ-123
- First posted
- 2014-04-28
- Last updated
- 2021-12-20
- Results first posted
- 2021-12-20
Source ClinicalTrials.gov
Registered outcomes1
Each outcome the trial registered, primary first, in ClinicalTrials.gov's words.
| List | Outcome | Time frame | Description |
|---|---|---|---|
| Primary | Blood Flow | two years | Ultrasound Doppler |
Source ClinicalTrials.gov
Outcomes1
Each outcome the trial posted results for, in ClinicalTrials.gov's words.
| Type | Outcome | Time frame | Population | Units | Measured as |
|---|---|---|---|---|---|
| PRIMARY | Blood Flow | two years | ml/min | MEAN |
Source ClinicalTrials.gov
Results by group2
Each measurement the trial posted, group by group, in the words and numbers it posted.
| Outcome | Group | Category | Value | Spread | Units |
|---|---|---|---|---|---|
| Blood Flow | Arm 1: Control | 300 | Standard Error 50 | ml/min | |
| Blood Flow | Arm 2: Heart Failure | 275 | Standard Error 45 | ml/min |
Source ClinicalTrials.gov
Participant flow6
How many started, completed or left each group, period by period.
| Period | Milestone | Group | Participants | Units counted |
|---|---|---|---|---|
| Overall Study | STARTED | Arm 1: Control | 15 | |
| Overall Study | STARTED | Arm 2: Heart Failure | 15 | |
| Overall Study | COMPLETED | Arm 1: Control | 15 | |
| Overall Study | COMPLETED | Arm 2: Heart Failure | 15 | |
| Overall Study | NOT COMPLETED | Arm 1: Control | 0 | |
| Overall Study | NOT COMPLETED | Arm 2: Heart Failure | 0 |
Source ClinicalTrials.gov
Adverse events0
Each adverse event the trial posted, group by group: the participants affected out of those at risk.
None in this release.
Adverse event totals6
The totals the trial posted for each group.
| Total | Group | Affected | At risk |
|---|---|---|---|
| Total, all-cause mortality | Arm 1: Control | 0 | 15 |
| Total, all-cause mortality | Arm 2: Heart Failure | 0 | 15 |
| Total, other adverse events | Arm 1: Control | 0 | 15 |
| Total, other adverse events | Arm 2: Heart Failure | 0 | 15 |
| Total, serious adverse events | Arm 1: Control | 0 | 15 |
| Total, serious adverse events | Arm 2: Heart Failure | 0 | 15 |
Source ClinicalTrials.gov
Papers0
The papers the trial lists on ClinicalTrials.gov.
None in this release.
Grants0
The grants NIH RePORTER links to the trial, newest funded first: NIH's, and some of AHRQ's, CDC's, FDA's and VA's. Each shows its title, principal investigators, organization and funder in its newest year.
None in this release.
Trial comparisons2
Comparisons of the trial's two groups, calculated by ConductScience from the counts it posted.
| Comparison | Source |
|---|---|
| Arm 2: Heart Failure vs Arm 1: Control: deaths from any cause | Trial comparisons |
| Arm 2: Heart Failure vs Arm 1: Control: serious adverse events | Trial comparisons |
Tests0
The ConductCognition tests this trial's registered outcomes name, as ScienceGraph matched them in trial-tests-2026-11-12-0.2.1.
None in this release.
Data dates
The day each source was copied for this release.
Sources 3
- ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
- ClinicalTrials.govNo license stated
- NIH RePORTER's clinical studies and project filesPublic domain
Each source's terms
- ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
- ClinicalTrials.govnone stated
- NIH RePORTER's clinical studies and project filesPublic domain (NIH RePORTER)
ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.
For software
Read this trial from software.
The record and each of its lists are JSON, twenty rows a page. No key.
GET https://conductscience.org/api/trials/v1/NCT02124824
GET https://conductscience.org/api/trials/v1/NCT02124824/registered