Trial · NCT02132767

Rate Control Versus Rhythm Control For Postoperative Atrial Fibrillation

NCT02132767, Phase 3, Completed, Icahn School of Medicine at Mount Sinai; results first posted 2017-01-18

3 sourcestrials-2026-11-12-0.5.0

Cite this record

ConductScience Library. Rate Control Versus Rhythm Control For Postoperative Atrial Fibrillation. Trials, record NCT02132767. Release trials-2026-11-12-0.5.0, 12 Nov 2026. https://conductscience.org/library/trials/NCT02132767

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Trial

As registered on ClinicalTrials.gov, in the graph's capture of the registry.

Title: Rate Control Versus Rhythm Control For Postoperative Atrial Fibrillation
NCT number: NCT02132767
Status: Completed
Phases: Phase 3
Enrollment: 523 participants, actual
Lead sponsor: Icahn School of Medicine at Mount Sinai
Conditions: Postoperative Atrial Fibrillation
Interventions: Amiodarone, DC-cardioversion, Rate Control
First posted: 2014-05-07
Last updated: 2019-03-15
Results first posted: 2017-01-18

Source ClinicalTrials.gov

Registered outcomes10

Each outcome the trial registered, primary first, in ClinicalTrials.gov's words.

List	Outcome	Time frame	Description
Primary	Total Number of Days in Hospital	Within 60 days of randomization	The total number of days in hospital for any hospitalization that occurs within 60 days of randomization to AF treatment strategy.
Secondary	Time to Conversion to Sustained, Stable Non-AF Rhythm	Up to index hospital discharge or 7 days post surgery, whichever came first
Secondary	Heart Rhythm Comparison	Hospital discharge	Compare heart rhythm (number of patients in sustained, stable non-AF rhythm) between treatment arms at hospital discharge
Secondary	Heart Rhythm Comparison	30 days after randomization	Compare heart rhythm (patients in sustained, stable non-AF rhythm) between treatment arms at 30 days after randomization
Secondary	Heart Rhythm Comparison	60 days after randomization	Compare heart rhythm (number of patients in sustained, stable non-AF rhythm) between treatment arms at 60 days after randomization
Secondary	Length of Stay (Index Hospitalization)	Within 60 days post surgery	Overall length of stay for the index hospitalization
Secondary	Length of Stay (Rehospitalization, Including ED Visits)	Within 60 days of randomization	Compare length of stay between groups for any cause and AF-related hospitalizations, including ED visits
Secondary	Outpatient Interventions	Within 60 days of randomization	Compare frequency of outpatient visits between groups for any cause and AF-related causes
Secondary	AF- or Treatment-related Events	Within 60 days of randomization
Secondary	Cost (Hospital)	Within 60 days of randomization	Compare cost of index hospitalization and cost of rehospitalizations (including ED visits) between groups

Source ClinicalTrials.gov

Outcomes10

Each outcome the trial posted results for, in ClinicalTrials.gov's words.

Type	Outcome	Time frame	Population	Units	Measured as
PRIMARY	Total Number of Days in Hospital	Within 60 days of randomization	All randomized patients (intent to treat)	days	MEDIAN
SECONDARY	Time to Conversion to Sustained, Stable Non-AF Rhythm	Up to index hospital discharge or 7 days post surgery, whichever came first	All randomized patients (intent to treat)	days	MEDIAN
SECONDARY	Heart Rhythm Comparison	Hospital discharge		participants	NUMBER
SECONDARY	Heart Rhythm Comparison	30 days after randomization		participants	NUMBER
SECONDARY	Heart Rhythm Comparison	60 days after randomization		participants	NUMBER
SECONDARY	Length of Stay (Index Hospitalization)	Within 60 days post surgery		days	MEDIAN
SECONDARY	Length of Stay (Rehospitalization, Including ED Visits)	Within 60 days of randomization		days	MEDIAN
SECONDARY	Outpatient Interventions	Within 60 days of randomization		hospital stays < 24 hours	NUMBER
SECONDARY	AF- or Treatment-related Events	Within 60 days of randomization
SECONDARY	Cost (Hospital)	Within 60 days of randomization

Source ClinicalTrials.gov

Results by group16

Each measurement the trial posted, group by group, in the words and numbers it posted.

Outcome	Group	Value	Spread	Units
Total Number of Days in Hospital	Rate Control	5.1	Inter-Quartile Range 3.0 to 7.4	days
Total Number of Days in Hospital	Rhythm Control	5.0	Inter-Quartile Range 3.2 to 7.5	days
Time to Conversion to Sustained, Stable Non-AF Rhythm	Rate Control	1.85	Inter-Quartile Range 0.46 to 4.81	days
Time to Conversion to Sustained, Stable Non-AF Rhythm	Rhythm Control	0.95	Inter-Quartile Range 0.27 to 3.21	days
Heart Rhythm Comparison	Rate Control	231		participants
Heart Rhythm Comparison	Rhythm Control	244		participants
Heart Rhythm Comparison	Rate Control	220		participants
Heart Rhythm Comparison	Rhythm Control	223		participants
Heart Rhythm Comparison	Rate Control	220		participants
Heart Rhythm Comparison	Rhythm Control	231		participants

1 to 10 of 16Source ClinicalTrials.gov

See all 16 results by group

Participant flow6

How many started, completed or left each group, period by period.

Period	Milestone	Group	Participants
Overall Study	STARTED	Rate Control	262
Overall Study	STARTED	Rhythm Control	261
Overall Study	COMPLETED	Rate Control	245
Overall Study	COMPLETED	Rhythm Control	246
Overall Study	NOT COMPLETED	Rate Control	17
Overall Study	NOT COMPLETED	Rhythm Control	15

Source ClinicalTrials.gov

Adverse events88

Each adverse event the trial posted, group by group: the participants affected out of those at risk.

Type	Event	Organ system	Group	Affected	At risk	Events
other	Bleeding	General disorders	Rate Control	2	262	2
other	Bleeding	General disorders	Rhythm Control	1	261	2
other	Cardiac Arrhythmias	Cardiac disorders	Rate Control	2	262	2
other	Cardiac Arrhythmias	Cardiac disorders	Rhythm Control	7	261	8
other	Major infection	Infections and infestations	Rate Control	17	262	18
other	Major infection	Infections and infestations	Rhythm Control	11	261	11
other	Pleural effusion	Respiratory, thoracic and mediastinal disorders	Rate Control	5	262	5
other	Pleural effusion	Respiratory, thoracic and mediastinal disorders	Rhythm Control	1	261	1
other	Renal events	Renal and urinary disorders	Rate Control	3	262	4
other	Renal events	Renal and urinary disorders	Rhythm Control	6	261	6

1 to 10 of 88Source ClinicalTrials.gov

See all 88 adverse events

Adverse event totals6

The totals the trial posted for each group.

Total	Group	Affected	At risk
Total, all-cause mortality	Rate Control
Total, all-cause mortality	Rhythm Control
Total, other adverse events	Rate Control	29	262
Total, other adverse events	Rhythm Control	26	261
Total, serious adverse events	Rate Control	71	262
Total, serious adverse events	Rhythm Control	73	261

Source ClinicalTrials.gov

Papers2

The papers the trial lists on ClinicalTrials.gov.

PMID	Listed as	Source
27043047	DERIVED	PubMed
29043263	DERIVED	PubMed

Grants1

The grants NIH RePORTER links to the trial, newest funded first: NIH's, and some of AHRQ's, CDC's, FDA's and VA's. Each shows its title, principal investigators, organization and funder in its newest year.

Project	Title	Principal investigators	Organization	Funder	Fiscal years
U01HL088942	Network for Cardiothoracic Surgical Investigations in Cardiovascular Medicine	GELIJNS, ANNE CHRISTINE; MOSKOWITZ, ALAN J	ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI	NATIONAL HEART, LUNG, AND BLOOD INSTITUTE	2007 to 2025

Source NIH RePORTER

Trial comparisons4

Comparisons of the trial's two groups, calculated by ConductScience from the counts it posted.

Comparison	Source
Rate Control vs Rhythm Control: Heart Rhythm Comparison	Trial comparisons
Rate Control vs Rhythm Control: Heart Rhythm Comparison	Trial comparisons
Rate Control vs Rhythm Control: Heart Rhythm Comparison	Trial comparisons
Rate Control vs Rhythm Control: serious adverse events	Trial comparisons

Tests0

The ConductCognition tests this trial's registered outcomes name, as ScienceGraph matched them in trial-tests-2026-11-12-0.2.1.

None in this release.

Data dates

The day each source was copied for this release.

ClinicalTrials.gov: 2026-11-12; ClinicalTrials.gov
Results, from AACT: 2026-03-23; AACT
NIH grant links: 2026-11-13; NIH RePORTER

Sources 3

ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
ClinicalTrials.govNo license stated
NIH RePORTER's clinical studies and project filesPublic domain

Each source's terms

ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
ClinicalTrials.govnone stated
NIH RePORTER's clinical studies and project filesPublic domain (NIH RePORTER)

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

For software

Read this trial from software.

The record and each of its lists are JSON, twenty rows a page. No key.

GET https://conductscience.org/api/trials/v1/NCT02132767

GET https://conductscience.org/api/trials/v1/NCT02132767/events?page=2

API reference For AI assistants