Trial · NCT02137707
Biologic Basis for Multiple Sclerosis Disease Progression in RRMS Patients Treated With Gilenya
NCT02137707, Completed, McGill University
3 sourcestrials-2026-11-12-0.5.0
Cite this record
ConductScience Library. Biologic Basis for Multiple Sclerosis Disease Progression in RRMS Patients Treated With Gilenya. Trials, record NCT02137707. Release trials-2026-11-12-0.5.0, 12 Nov 2026. https://conductscience.org/library/trials/NCT02137707
On this page
Trial
As registered on ClinicalTrials.gov, in the graph's capture of the registry.
- Title
- Biologic Basis for Multiple Sclerosis Disease Progression in RRMS Patients Treated With Gilenya
- NCT number
- NCT02137707
- Status
- Completed
- Enrollment
- 135 participants, actual
- Lead sponsor
- McGill University
- Conditions
- Multiple Sclerosis-Relapsing-Remitting
- Interventions
- Gilenya
- First posted
- 2014-05-14
- Last updated
- 2018-11-09
Source ClinicalTrials.gov
Registered outcomes4
Each outcome the trial registered, primary first, in ClinicalTrials.gov's words.
| List | Outcome | Time frame | Description |
|---|---|---|---|
| Primary | Determination of disease progression of subjects treated with Gilenya over 2 years | 2 years | Changes in number of new and enlarging T2 lesions by MRI between baseline and Year 2 will be compared with immune biomarkers (Teff:Treg ratio) |
| Secondary | Change in cognitive function in patients treated with Gilenya | 2 years | changes in brain volume assessed by MRI between baseline and Year 2 will be compared with immune biomarkers |
| Secondary | Changes in biologic measures in patients treated with Gilenya | 2 years | change in MTR MRI as assessment of myelin content will be compared with blood biomarkers |
| Secondary | Safety and tolerability of Gilenya therapy will be assessed | 2 years | Safety parameters include the initial cardiac effects, liver function, infections and migraines/headaches |
Source ClinicalTrials.gov
Outcomes0
Each outcome the trial posted results for, in ClinicalTrials.gov's words.
None in this release.
Results by group0
Each measurement the trial posted, group by group, in the words and numbers it posted.
None in this release.
Participant flow0
How many started, completed or left each group, period by period.
None in this release.
Adverse events0
Each adverse event the trial posted, group by group: the participants affected out of those at risk.
None in this release.
Adverse event totals0
The totals the trial posted for each group.
None in this release.
Papers1
The papers the trial lists on ClinicalTrials.gov.
| PMID | Listed as |
|---|---|
| 31941953 | DERIVED |
Source PubMed
Grants0
The grants NIH RePORTER links to the trial, newest funded first: NIH's, and some of AHRQ's, CDC's, FDA's and VA's. Each shows its title, principal investigators, organization and funder in its newest year.
None in this release.
Trial comparisons0
Comparisons of the trial's two groups, calculated by ConductScience from the counts it posted.
None in this release.
Tests0
The ConductCognition tests this trial's registered outcomes name, as ScienceGraph matched them in trial-tests-2026-11-12-0.2.1.
None in this release.
Data dates
The day each source was copied for this release.
Sources 3
- ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
- ClinicalTrials.govNo license stated
- NIH RePORTER's clinical studies and project filesPublic domain
Each source's terms
- ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
- ClinicalTrials.govnone stated
- NIH RePORTER's clinical studies and project filesPublic domain (NIH RePORTER)
ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.
For software
Read this trial from software.
The record and each of its lists are JSON, twenty rows a page. No key.
GET https://conductscience.org/api/trials/v1/NCT02137707
GET https://conductscience.org/api/trials/v1/NCT02137707/registered