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Trial · NCT02160145

Results by group24

Each measurement the trial posted, group by group, in the words and numbers it posted.

OutcomeGroupCategoryValueSpreadUnits
The Mean Annualized Change in eGFR From Pretreatment Baseline to Post-treatment Follow-up.Tolvaptan-2.339Standard Error 0.240mL/min/1.73 m^2/year
The Mean Annualized Change in eGFR From Pretreatment Baseline to Post-treatment Follow-up.Placebo-3.610Standard Error 0.240mL/min/1.73 m^2/year
Mean Annualized Slope of eGFR ChangeTolvaptan-3.160Standard Error 0.140mL/min/1.73m^2/year
Mean Annualized Slope of eGFR ChangePlacebo-4.170Standard Error 0.142mL/min/1.73m^2/year
Mean Change From Baseline in Urine Osmolality During the Double-blind Treatment Period and Post-treatment Follow-upTolvaptanMonth 310.2Standard Deviation 80.3milliosmole per kilogram (mOSm/kg)
Mean Change From Baseline in Urine Osmolality During the Double-blind Treatment Period and Post-treatment Follow-upPlaceboMonth 3177.7Standard Deviation 124.5milliosmole per kilogram (mOSm/kg)
Mean Change From Baseline in Urine Osmolality During the Double-blind Treatment Period and Post-treatment Follow-upTolvaptanMonth 622.9Standard Deviation 84.3milliosmole per kilogram (mOSm/kg)
Mean Change From Baseline in Urine Osmolality During the Double-blind Treatment Period and Post-treatment Follow-upPlaceboMonth 6179.1Standard Deviation 126.2milliosmole per kilogram (mOSm/kg)
Mean Change From Baseline in Urine Osmolality During the Double-blind Treatment Period and Post-treatment Follow-upTolvaptanMonth 930.4Standard Deviation 92.1milliosmole per kilogram (mOSm/kg)
Mean Change From Baseline in Urine Osmolality During the Double-blind Treatment Period and Post-treatment Follow-upPlaceboMonth 9179.9Standard Deviation 125.1milliosmole per kilogram (mOSm/kg)
Mean Change From Baseline in Urine Osmolality During the Double-blind Treatment Period and Post-treatment Follow-upTolvaptanMonth1236.9Standard Deviation 96.0milliosmole per kilogram (mOSm/kg)
Mean Change From Baseline in Urine Osmolality During the Double-blind Treatment Period and Post-treatment Follow-upPlaceboMonth12180.3Standard Deviation 121.1milliosmole per kilogram (mOSm/kg)
Mean Change From Baseline in Urine Osmolality During the Double-blind Treatment Period and Post-treatment Follow-upTolvaptanFollow-up162.4Standard Deviation 114.0milliosmole per kilogram (mOSm/kg)
Mean Change From Baseline in Urine Osmolality During the Double-blind Treatment Period and Post-treatment Follow-upPlaceboFollow-up179.5Standard Deviation 128.9milliosmole per kilogram (mOSm/kg)
Mean Change From Baseline in Urine Specific Gravity During the Double-blind Treatment Period and Post-treatment Follow-upTolvaptanMonth 30.0001Standard Deviation 0.0022unitless
Mean Change From Baseline in Urine Specific Gravity During the Double-blind Treatment Period and Post-treatment Follow-upPlaceboMonth 30.0041Standard Deviation 0.0033unitless
Mean Change From Baseline in Urine Specific Gravity During the Double-blind Treatment Period and Post-treatment Follow-upTolvaptanMonth 60.0003Standard Deviation 0.0024unitless
Mean Change From Baseline in Urine Specific Gravity During the Double-blind Treatment Period and Post-treatment Follow-upPlaceboMonth 60.0042Standard Deviation 0.0033unitless
Mean Change From Baseline in Urine Specific Gravity During the Double-blind Treatment Period and Post-treatment Follow-upTolvaptanMonth 90.004Standard Deviation 0.0025unitless
Mean Change From Baseline in Urine Specific Gravity During the Double-blind Treatment Period and Post-treatment Follow-upPlaceboMonth 90.0040Standard Deviation 0.0032unitless

Source ClinicalTrials.govtrials-2026-11-12-0.5.0

Sources 3

  • ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
  • ClinicalTrials.govNo license stated
  • NIH RePORTER's clinical studies and project filesPublic domain
Each source's terms
  • ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
  • ClinicalTrials.govnone stated
  • NIH RePORTER's clinical studies and project filesPublic domain (NIH RePORTER)

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

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