Trial · NCT02187848
Evaluation of SAR408701 in Patients With Advanced Solid Tumors
NCT02187848, Phase 1, Terminated, Sanofi
3 sourcestrials-2026-11-12-0.5.0
Cite this record
ConductScience Library. Evaluation of SAR408701 in Patients With Advanced Solid Tumors. Trials, record NCT02187848. Release trials-2026-11-12-0.5.0, 12 Nov 2026. https://conductscience.org/library/trials/NCT02187848
On this page
Trial
As registered on ClinicalTrials.gov, in the graph's capture of the registry.
- Title
- Evaluation of SAR408701 in Patients With Advanced Solid Tumors
- NCT number
- NCT02187848
- Status
- Terminated
- Phases
- Phase 1
- Enrollment
- 254 participants, actual
- Lead sponsor
- Sanofi
- Conditions
- Neoplasm Malignant
- Interventions
- SAR408701
- First posted
- 2014-07-11
- Last updated
- 2025-02-10
- Other registries' IDs
- eudract:2014-001130-29
Source ClinicalTrials.gov
Registered outcomes14
Each outcome the trial registered, primary first, in ClinicalTrials.gov's words.
| List | Outcome | Time frame | Description |
|---|---|---|---|
| Primary | Number of dose limiting adverse events (every 2 week cycle) | 4 weeks | |
| Primary | Assessment of overall response rate using standard imaging and RECIST 1.1 criteria | Up to 40 months | |
| Primary | Number of dose limiting adverse events (every 3 week cycle) | 3 weeks | |
| Secondary | Number of treatment emergent adverse events | Up to 4 years | |
| Secondary | Maximum concentration (Cmax) | 2 months | |
| Secondary | Time to reach maximum concentration (tmax) | 2 months | |
| Secondary | Trough plasma concentrations (Ctrough) | Intensive testing within first 2 months, then every 2 weeks | |
| Secondary | Area under the plasma concentration versus time curve between 0 and 14 days (AUC0-14day) for Q2W or between 0 and 21 days (AUC-21 day) for Q3W | 2 months | |
| Secondary | Mean systemic clearance (CL) | 2 months | |
| Secondary | Clearance at steady state (CLss) | 2 months |
1 to 10 of 14Source ClinicalTrials.gov
See all 14 registered outcomesOutcomes0
Each outcome the trial posted results for, in ClinicalTrials.gov's words.
None in this release.
Results by group0
Each measurement the trial posted, group by group, in the words and numbers it posted.
None in this release.
Participant flow0
How many started, completed or left each group, period by period.
None in this release.
Adverse events0
Each adverse event the trial posted, group by group: the participants affected out of those at risk.
None in this release.
Adverse event totals0
The totals the trial posted for each group.
None in this release.
Papers3
The papers the trial lists on ClinicalTrials.gov.
Grants0
The grants NIH RePORTER links to the trial, newest funded first: NIH's, and some of AHRQ's, CDC's, FDA's and VA's. Each shows its title, principal investigators, organization and funder in its newest year.
None in this release.
Trial comparisons0
Comparisons of the trial's two groups, calculated by ConductScience from the counts it posted.
None in this release.
Tests0
The ConductCognition tests this trial's registered outcomes name, as ScienceGraph matched them in trial-tests-2026-11-12-0.2.1.
None in this release.
Data dates
The day each source was copied for this release.
Sources 3
- ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
- ClinicalTrials.govNo license stated
- NIH RePORTER's clinical studies and project filesPublic domain
Each source's terms
- ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
- ClinicalTrials.govnone stated
- NIH RePORTER's clinical studies and project filesPublic domain (NIH RePORTER)
ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.
For software
Read this trial from software.
The record and each of its lists are JSON, twenty rows a page. No key.
GET https://conductscience.org/api/trials/v1/NCT02187848
GET https://conductscience.org/api/trials/v1/NCT02187848/registered