Trial · NCT02255461
Results by group71
Each measurement the trial posted, group by group, in the words and numbers it posted.
1 to 20 of 71
Download this page as JSON| Outcome | Group | Category | Value | Spread | Units |
|---|---|---|---|---|---|
| Maximum Tolerated Dose (MTD) of Palbociclib in Stratum I | Stratum I | 75 | mg/m2/day | ||
| Maximum Tolerated Dose (MTD) of Palbociclib in Stratum II | Stratum II | 75 | mg/m2/day | ||
| Number of Patients Who Experienced Dose Limiting Toxicities (DLTs) | Stratum I, Dose Level 1 (50 mg/m2) | 0 | Participants | ||
| Number of Patients Who Experienced Dose Limiting Toxicities (DLTs) | Stratum I, Dose Level 2 (75 mg/m2) | 2 | Participants | ||
| Number of Patients Who Experienced Dose Limiting Toxicities (DLTs) | Stratum I, Dose Level 3 (95 mg/m2) | 2 | Participants | ||
| Number of Patients Who Experienced Dose Limiting Toxicities (DLTs) | Stratum II, Dose Level 1 (50 mg/m2) | 0 | Participants | ||
| Number of Patients Who Experienced Dose Limiting Toxicities (DLTs) | Stratum II, Dose Level 2 (75mg/m2) | 1 | Participants | ||
| Single Dose Apparent Volume of Central Compartment (Vc/F) | Stratum I, Dose Level 1 (50 mg/m2) | 672 | Full Range 622 to 1189 | L/m^2 | |
| Single Dose Apparent Volume of Central Compartment (Vc/F) | Stratum I, Dose Level 2 (75 mg/m2) | 741 | Full Range 562 to 1856 | L/m^2 | |
| Single Dose Apparent Volume of Central Compartment (Vc/F) | Stratum I, Dose Level 3 (95 mg/m2) | 708 | Full Range 601 to 819 | L/m^2 | |
| Single Dose Apparent Volume of Central Compartment (Vc/F) | Stratum II, Dose Level 1 (50 mg/m2) | 847 | Full Range 373 to 1153 | L/m^2 | |
| Single Dose Apparent Volume of Central Compartment (Vc/F) | Stratum II, Dose Level 2 (75mg/m2) | 850 | Full Range 398 to 3653 | L/m^2 | |
| Single Dose Elimination Rate Constant (Ke) | Stratum I, Dose Level 1 (50 mg/m2) | 0.053 | Full Range 0.045 to 0.055 | per hour | |
| Single Dose Elimination Rate Constant (Ke) | Stratum I, Dose Level 2 (75 mg/m2) | 0.053 | Full Range 0.030 to 0.070 | per hour | |
| Single Dose Elimination Rate Constant (Ke) | Stratum I, Dose Level 3 (95 mg/m2) | 0.048 | Full Range 0.023 to 0.083 | per hour | |
| Single Dose Elimination Rate Constant (Ke) | Stratum II, Dose Level 1 (50 mg/m2) | 0.051 | Full Range 0.031 to 0.070 | per hour | |
| Single Dose Elimination Rate Constant (Ke) | Stratum II, Dose Level 2 (75mg/m2) | 0.051 | Full Range 0.014 to 0.097 | per hour | |
| Single Dose Half-life (t1/2) | Stratum I, Dose Level 1 (50 mg/m2) | 13.0 | Full Range 12.5 to 15.5 | hour | |
| Single Dose Half-life (t1/2) | Stratum I, Dose Level 2 (75 mg/m2) | 13.0 | Full Range 9.9 to 22.8 | hour | |
| Single Dose Half-life (t1/2) | Stratum I, Dose Level 3 (95 mg/m2) | 14.6 | Full Range 8.4 to 29.8 | hour |
Source ClinicalTrials.govtrials-2026-11-12-0.5.0
Sources 3
- ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
- ClinicalTrials.govNo license stated
- NIH RePORTER's clinical studies and project filesPublic domain
Each source's terms
- ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
- ClinicalTrials.govnone stated
- NIH RePORTER's clinical studies and project filesPublic domain (NIH RePORTER)
ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.
For software
Read this list from software.
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GET https://conductscience.org/api/trials/v1/NCT02255461/results