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Trial · NCT02262832

Compassionate Use of Metreleptin in Previously Treated People With Generalized Lipodystrophy

NCT02262832, Phase 3, Active not recruiting, National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)

3 sourcestrials-2026-11-12-0.5.0

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ConductScience Library. Compassionate Use of Metreleptin in Previously Treated People With Generalized Lipodystrophy. Trials, record NCT02262832. Release trials-2026-11-12-0.5.0, 12 Nov 2026. https://conductscience.org/library/trials/NCT02262832

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Trial

As registered on ClinicalTrials.gov, in the graph's capture of the registry.

Title
Compassionate Use of Metreleptin in Previously Treated People With Generalized Lipodystrophy
NCT number
NCT02262832
Status
Active not recruiting
Phases
Phase 3
Enrollment
24 participants, actual
Lead sponsor
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Conditions
Lipodystrophy, Diabetes, Hyperlipidemia
Interventions
Metreleptin
First posted
2014-10-13
Last updated
2026-10-27

Source ClinicalTrials.gov

Registered outcomes6

Each outcome the trial registered, primary first, in ClinicalTrials.gov's words.

ListOutcomeTime frameDescription
PrimarySerum triglyceridesevery 6-12 monthsImprovements in lab value.
PrimarySerum hemoglobin A1Cevery 6-12 monthsImprovements in lab value.
SecondarySteatohepatosisevery 12 monthsstable or improvements
SecondaryPituitary & Reproductive Functionevery 6-12 monthsstable or improvements
SecondaryEctopic lipid & body compositionevery 12 monthsstable or improvements
SecondaryBone mineral density & metabolismevery 12 monthsstable or improvements

Outcomes0

Each outcome the trial posted results for, in ClinicalTrials.gov's words.

None in this release.

Results by group0

Each measurement the trial posted, group by group, in the words and numbers it posted.

None in this release.

Participant flow0

How many started, completed or left each group, period by period.

None in this release.

Adverse events0

Each adverse event the trial posted, group by group: the participants affected out of those at risk.

None in this release.

Adverse event totals0

The totals the trial posted for each group.

None in this release.

Papers3

The papers the trial lists on ClinicalTrials.gov.

PMIDListed asSource
28324110DERIVEDPubMed
30237235BACKGROUNDPubMed
30847226BACKGROUNDPubMed

Grants0

The grants NIH RePORTER links to the trial, newest funded first: NIH's, and some of AHRQ's, CDC's, FDA's and VA's. Each shows its title, principal investigators, organization and funder in its newest year.

None in this release.

Trial comparisons0

Comparisons of the trial's two groups, calculated by ConductScience from the counts it posted.

None in this release.

Tests0

The ConductCognition tests this trial's registered outcomes name, as ScienceGraph matched them in trial-tests-2026-11-12-0.2.1.

None in this release.

Data dates

The day each source was copied for this release.

ClinicalTrials.gov
2026-11-12
ClinicalTrials.gov
Results, from AACT
2026-03-23
AACT
NIH grant links
2026-11-13
NIH RePORTER

Sources 3

  • ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
  • ClinicalTrials.govNo license stated
  • NIH RePORTER's clinical studies and project filesPublic domain
Each source's terms
  • ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
  • ClinicalTrials.govnone stated
  • NIH RePORTER's clinical studies and project filesPublic domain (NIH RePORTER)

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

For software

Read this trial from software.

The record and each of its lists are JSON, twenty rows a page. No key.

GET https://conductscience.org/api/trials/v1/NCT02262832

GET https://conductscience.org/api/trials/v1/NCT02262832/registered