Trial · NCT02272816
Carboplatin AUC-10 With Early PET Scanning in Metastatic Seminoma
NCT02272816, Phase 2, Completed, Barts & The London NHS Trust; results first posted 2019-01-25
3 sourcestrials-2026-11-12-0.5.0
Cite this record
ConductScience Library. Carboplatin AUC-10 With Early PET Scanning in Metastatic Seminoma. Trials, record NCT02272816. Release trials-2026-11-12-0.5.0, 12 Nov 2026. https://conductscience.org/library/trials/NCT02272816
On this page
Trial
As registered on ClinicalTrials.gov, in the graph's capture of the registry.
- Title
- Carboplatin AUC-10 With Early PET Scanning in Metastatic Seminoma
- NCT number
- NCT02272816
- Status
- Completed
- Phases
- Phase 2
- Enrollment
- 48 participants, actual
- Lead sponsor
- Barts & The London NHS Trust
- Conditions
- Metastatic Seminoma
- Interventions
- Carboplatin AUC-10
- First posted
- 2014-10-23
- Last updated
- 2019-01-25
- Other registries' IDs
- eudract:2009-009882-33
- Results first posted
- 2019-01-25
Source ClinicalTrials.gov
Registered outcomes3
Each outcome the trial registered, primary first, in ClinicalTrials.gov's words.
| List | Outcome | Time frame | Description |
|---|---|---|---|
| Primary | 2 - Year Progression Free Survival | 2 years | Number of participants progression free 2 years after registration. |
| Secondary | Metabolic Response Rate | 21 days | Number of participants achieving i) complete metabolic response (CR) and ii) partial metabolic response (PR) after one cycle of treatment. |
| Secondary | Overall Survival | 2 years | Survival status at 2 years after registration. |
Source ClinicalTrials.gov
Outcomes3
Each outcome the trial posted results for, in ClinicalTrials.gov's words.
| Type | Outcome | Time frame | Population | Units | Measured as |
|---|---|---|---|---|---|
| PRIMARY | 2 - Year Progression Free Survival | 2 years | All participants who received at least one dose of study treatment. | Participants | COUNT_OF_PARTICIPANTS |
| SECONDARY | Metabolic Response Rate | 21 days | All participants who completed one cycle of treatment and underwent PET-CT scan on day 17-21. | Participants | COUNT_OF_PARTICIPANTS |
| SECONDARY | Overall Survival | 2 years | All participants who received at least one dose of study treatment. | Participants | COUNT_OF_PARTICIPANTS |
Source ClinicalTrials.gov
Results by group5
Each measurement the trial posted, group by group, in the words and numbers it posted.
| Outcome | Group | Category | Value | Spread | Units |
|---|---|---|---|---|---|
| 2 - Year Progression Free Survival | Carboplatin AUC-10 | 46 | Participants | ||
| Metabolic Response Rate | Carboplatin AUC-10 | CR | 21 | Participants | |
| Metabolic Response Rate | Carboplatin AUC-10 | PR | 26 | Participants | |
| Overall Survival | Carboplatin AUC-10 | Alive | 48 | Participants | |
| Overall Survival | Carboplatin AUC-10 | Deceased | 0 | Participants |
Source ClinicalTrials.gov
Participant flow3
How many started, completed or left each group, period by period.
| Period | Milestone | Group | Participants | Units counted |
|---|---|---|---|---|
| Overall Study | STARTED | Carboplatin AUC-10 | 48 | |
| Overall Study | COMPLETED | Carboplatin AUC-10 | 47 | |
| Overall Study | NOT COMPLETED | Carboplatin AUC-10 | 1 |
Source ClinicalTrials.gov
Adverse events47
Each adverse event the trial posted, group by group: the participants affected out of those at risk.
| Type | Event | Organ system | Group | Affected | At risk | Events |
|---|---|---|---|---|---|---|
| other | Hypertension | Vascular disorders | Carboplatin AUC-10 | 1 | 48 | 1 |
| other | Fatigue | General disorders | Carboplatin AUC-10 | 44 | 48 | 111 |
| other | Pain | General disorders | Carboplatin AUC-10 | 6 | 48 | 7 |
| other | Depression | Psychiatric disorders | Carboplatin AUC-10 | 1 | 48 | 1 |
| other | Insomnia | Psychiatric disorders | Carboplatin AUC-10 | 3 | 48 | 4 |
| other | Mood swings | Psychiatric disorders | Carboplatin AUC-10 | 1 | 48 | 1 |
| other | Sunburn | Injury, poisoning and procedural complications | Carboplatin AUC-10 | 1 | 48 | 1 |
| other | Neutrophil count decreased | Investigations | Carboplatin AUC-10 | 34 | 48 | 81 |
| other | Platelet count decreased | Investigations | Carboplatin AUC-10 | 28 | 48 | 53 |
| other | Weight decreased | Investigations | Carboplatin AUC-10 | 1 | 48 | 1 |
1 to 10 of 47Source ClinicalTrials.gov
See all 47 adverse eventsAdverse event totals3
The totals the trial posted for each group.
| Total | Group | Affected | At risk |
|---|---|---|---|
| Total, all-cause mortality | Carboplatin AUC-10 | 0 | 48 |
| Total, other adverse events | Carboplatin AUC-10 | 47 | 48 |
| Total, serious adverse events | Carboplatin AUC-10 | 12 | 48 |
Source ClinicalTrials.gov
Papers10
The papers the trial lists on ClinicalTrials.gov.
Grants0
The grants NIH RePORTER links to the trial, newest funded first: NIH's, and some of AHRQ's, CDC's, FDA's and VA's. Each shows its title, principal investigators, organization and funder in its newest year.
None in this release.
Trial comparisons0
Comparisons of the trial's two groups, calculated by ConductScience from the counts it posted.
None in this release.
Tests0
The ConductCognition tests this trial's registered outcomes name, as ScienceGraph matched them in trial-tests-2026-11-12-0.2.1.
None in this release.
Data dates
The day each source was copied for this release.
Sources 3
- ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
- ClinicalTrials.govNo license stated
- NIH RePORTER's clinical studies and project filesPublic domain
Each source's terms
- ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
- ClinicalTrials.govnone stated
- NIH RePORTER's clinical studies and project filesPublic domain (NIH RePORTER)
ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.
For software
Read this trial from software.
The record and each of its lists are JSON, twenty rows a page. No key.
GET https://conductscience.org/api/trials/v1/NCT02272816
GET https://conductscience.org/api/trials/v1/NCT02272816/events?page=2