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Trial · NCT02279641

Registered outcomes13

Each outcome the trial registered, primary first, in ClinicalTrials.gov's words.

ListOutcomeTime frameDescription
PrimaryMaximum Observed Plasma Concentration (Cmax)22 daysCmax of Allopurinol/Oxypurinol Alone and In Combination with RDEA3170
PrimaryTime of Occurrence of Maximum Observed Concentration (Tmax)22 daysTmax of Allopurinol/Oxypurinol and RDEA3170 Alone and In Combination
PrimaryArea Under the Concentration-time Curve From Time Zero up to 24 Hours Postdose (AUC 0-24)22 daysAUC 0-24 of Allopurinol/Oxypurinol Alone and In Combination with RDEA3170
PrimaryArea Under the Concentration-time Curve From Time Zero to the Last Quantifiable Sampling Timepoint (AUC Last)22 daysAUC last of Allopurinol/Oxypurinol Alone and In Combination with RDEA3170
PrimaryApparent Terminal Half-life (t1/2)22 dayst1/2 of Allopurinol/Oxypurinol and RDEA3170 Alone and In Combination
PrimaryAmount Excreted in Urine as Unchanged Drug or Metabolite (Ae0-24)22 daysAe0-24 of Allopurinol/Oxypurinol Alone and In Combination with RDEA3170
PrimaryRenal Clearance of the Drug From Time Zero up to 24 Hours Postdose (CRL0-24)22 daysCLR0-24 of Allopurinol/Oxypurinol and RDEA3170 Alone and In Combination
PrimaryPharmacodynamics (PD) Profile of Uric Acid From Serum and Urine22 days
PrimaryMaximum Observed Plasma Concentration (Cmax)22 daysCmax of RDEA3170 Alone and In Combination with Allopurinol
PrimaryArea Under the Concentration-time Curve From Time Zero up to 24 Hours Postdose (AUC 0-24)22 daysAUC 0-24 of RDEA3170 Alone and In Combination with Allopurinol
PrimaryArea Under the Concentration-time Curve From Time Zero to the Last Quantifiable Sampling Timepoint (AUC Last)22 daysAUC last of RDEA3170 Alone and In Combination with Allopurinol
PrimaryAmount Excreted in Urine as Unchanged Drug or Metabolite (Ae0-24)22 daysAe0-24 of RDEA3170 Alone and In Combination with Allopurinol
SecondaryIncidence of Treatment-Emergent Adverse Events22 days

Source ClinicalTrials.govtrials-2026-11-12-0.4.0

Sources 3

  • ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
  • ClinicalTrials.govNo license stated
  • NIH RePORTER's clinical studies and project filesPublic domain
Each source's terms
  • ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
  • ClinicalTrials.govnone stated
  • NIH RePORTER's clinical studies and project filesPublic domain (NIH RePORTER)

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

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