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Trial · NCT02303821

Results by group136

Each measurement the trial posted, group by group, in the words and numbers it posted.

OutcomeGroupCategoryValueSpreadUnits
Phase 1b: Maximum Concentration (Cmax) of Carfilzomib Alone and in CombinationPhase 1b: Dose Escalation 1 (20 mg/m^2)Dose Escalation 1 - Lead in Cycle Day 1927Standard Deviation 259ng/mL
Phase 1b: Maximum Concentration (Cmax) of Carfilzomib Alone and in CombinationPhase 1b: Dose Escalation 1 (20/27 mg/m^2)Dose Escalation 1 - Lead in Cycle Day 1637Standard Deviation 241ng/mL
Phase 1b: Maximum Concentration (Cmax) of Carfilzomib Alone and in CombinationPhase 1b: Dose Escalation 1 (20 mg/m^2)Induction cycle Day 8771Standard Deviation 151ng/mL
Phase 1b: Maximum Concentration (Cmax) of Carfilzomib Alone and in CombinationPhase 1b: Dose Escalation 1 (20/27 mg/m^2)Induction cycle Day 8792Standard Deviation 580ng/mL
Phase 1b: Maximum Concentration (Cmax) of Carfilzomib Alone and in CombinationPhase 1b: Dose Escalation 2 (20/27 mg/m^2)Induction cycle Day 8445Standard Deviation 260ng/mL
Phase 1b: Maximum Concentration (Cmax) of Carfilzomib Alone and in CombinationPhase 1b: Dose Escalation 2 (20/36 mg/m^2)Induction cycle Day 81070Standard Deviation 359ng/mL
Phase 1b: Maximum Concentration (Cmax) of Carfilzomib Alone and in CombinationPhase 1b: Dose Escalation 2 (20/45 mg/m^2)Induction cycle Day 81630Standard Deviation 875ng/mL
Phase 1b: Maximum Concentration (Cmax) of Carfilzomib Alone and in CombinationPhase 1b: Dose Escalation 2 (20/56 mg/m^2)Induction cycle Day 811200Standard Deviation 16400ng/mL
Phase 1b: Area Under the Curve (AUC) From Time 0 to the Last Quantifiable Timepoint (AUClast) of CarfilzomibPhase 1b: Dose Escalation 1 (20 mg/m^2)Dose Escalation 1 - Lead in Cycle Day 1387Standard Deviation 125hr*ng/mL
Phase 1b: Area Under the Curve (AUC) From Time 0 to the Last Quantifiable Timepoint (AUClast) of CarfilzomibPhase 1b: Dose Escalation 1 (20/27 mg/m^2)Dose Escalation 1 - Lead in Cycle Day 1240Standard Deviation 113hr*ng/mL
Phase 1b: Area Under the Curve (AUC) From Time 0 to the Last Quantifiable Timepoint (AUClast) of CarfilzomibPhase 1b: Dose Escalation 1 (20 mg/m^2)Induction Cycle Day 8361Standard Deviation 160hr*ng/mL
Phase 1b: Area Under the Curve (AUC) From Time 0 to the Last Quantifiable Timepoint (AUClast) of CarfilzomibPhase 1b: Dose Escalation 1 (20/27 mg/m^2)Induction Cycle Day 8374Standard Deviation 273hr*ng/mL
Phase 1b: Area Under the Curve (AUC) From Time 0 to the Last Quantifiable Timepoint (AUClast) of CarfilzomibPhase 1b: Dose Escalation 2 (20/27 mg/m^2)Induction Cycle Day 8214Standard Deviation 155hr*ng/mL
Phase 1b: Area Under the Curve (AUC) From Time 0 to the Last Quantifiable Timepoint (AUClast) of CarfilzomibPhase 1b: Dose Escalation 2 (20/36 mg/m^2)Induction Cycle Day 8529Standard Deviation 210hr*ng/mL
Phase 1b: Area Under the Curve (AUC) From Time 0 to the Last Quantifiable Timepoint (AUClast) of CarfilzomibPhase 1b: Dose Escalation 2 (20/45 mg/m^2)Induction Cycle Day 8829Standard Deviation 479hr*ng/mL
Phase 1b: Area Under the Curve (AUC) From Time 0 to the Last Quantifiable Timepoint (AUClast) of CarfilzomibPhase 1b: Dose Escalation 2 (20/56 mg/m^2)Induction Cycle Day 84000Standard Deviation 6370hr*ng/mL
Phase 1b: AUC From Time 0 to Infinity (AUCinf) of CarfilzomibPhase 1b: Dose Escalation 1 (20 mg/m^2)Dose Escalation 1 - Lead in Cycle Day 1387Standard Deviation 124hr*ng/ mL
Phase 1b: AUC From Time 0 to Infinity (AUCinf) of CarfilzomibPhase 1b: Dose Escalation 1 (20/27 mg/m^2)Dose Escalation 1 - Lead in Cycle Day 1268Standard Deviation 101hr*ng/ mL
Phase 1b: AUC From Time 0 to Infinity (AUCinf) of CarfilzomibPhase 1b: Dose Escalation 1 (20 mg/m^2)Induction Cycle Day 8368Standard Deviation 184hr*ng/ mL
Phase 1b: AUC From Time 0 to Infinity (AUCinf) of CarfilzomibPhase 1b: Dose Escalation 1 (20/27 mg/m^2)Induction Cycle Day 8374Standard Deviation 273hr*ng/ mL

Source ClinicalTrials.govtrials-2026-11-12-0.5.0

Sources 3

  • ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
  • ClinicalTrials.govNo license stated
  • NIH RePORTER's clinical studies and project filesPublic domain
Each source's terms
  • ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
  • ClinicalTrials.govnone stated
  • NIH RePORTER's clinical studies and project filesPublic domain (NIH RePORTER)

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

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