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Trial · NCT02307500

Regorafenib in Patients With Metastatic Solid Tumors Who Have Progressed After Standard Therapy

NCT02307500, Phase 2, Completed, Istituto Clinico Humanitas

3 sourcestrials-2026-11-12-0.5.0

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ConductScience Library. Regorafenib in Patients With Metastatic Solid Tumors Who Have Progressed After Standard Therapy. Trials, record NCT02307500. Release trials-2026-11-12-0.5.0, 12 Nov 2026. https://conductscience.org/library/trials/NCT02307500

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Trial

As registered on ClinicalTrials.gov, in the graph's capture of the registry.

Title
Regorafenib in Patients With Metastatic Solid Tumors Who Have Progressed After Standard Therapy
NCT number
NCT02307500
Status
Completed
Phases
Phase 2
Enrollment
82 participants, actual
Lead sponsor
Istituto Clinico Humanitas
Conditions
Pancreas Cancer, Ovarian Cancer, Melanoma, Sarcoma, Thymoma Type B3, Thymoma Type B2, Thymic Carcinoma
Interventions
Regorafenib
First posted
2014-12-04
Last updated
2022-09-10

Source ClinicalTrials.gov

Registered outcomes4

Each outcome the trial registered, primary first, in ClinicalTrials.gov's words.

ListOutcomeTime frameDescription
Primaryactivity of regorafenib screening, in terms of 2-months progression free survival rate2 monthsto evaluate activity of regorafenib, in terms of 2-months progression free survival rate
Secondaryprognosis in terms of progression-free survival36 monthsto explore the prognosis in terms of progression-free survival calculated from the first day of regorafenib treatment to the date of tumor progression or death, whichever occurs first.
Secondaryoverall survival (OS)36 monthsto explore overall survival (OS) measured from the first day of regorafenib treatment until the date of death from any cause or the date of the last contact, at which the patients will be censored
Secondarysafety profile of regorafenib according to NCI-CTC v.33 monthsto assess the safety profile of regorafenib according to the National Cancer Institute Common Toxicity Criteria (NCI-CTC) version 3

Outcomes0

Each outcome the trial posted results for, in ClinicalTrials.gov's words.

None in this release.

Results by group0

Each measurement the trial posted, group by group, in the words and numbers it posted.

None in this release.

Participant flow0

How many started, completed or left each group, period by period.

None in this release.

Adverse events0

Each adverse event the trial posted, group by group: the participants affected out of those at risk.

None in this release.

Adverse event totals0

The totals the trial posted for each group.

None in this release.

Papers29

The papers the trial lists on ClinicalTrials.gov.

PMIDListed asSource
7596435BACKGROUNDPubMed
7596436BACKGROUNDPubMed
8193545BACKGROUNDPubMed
11001067BACKGROUNDPubMed
11001068BACKGROUNDPubMed
11896121BACKGROUNDPubMed
11927284BACKGROUNDPubMed
12124170BACKGROUNDPubMed
12181402BACKGROUNDPubMed
12360282BACKGROUNDPubMed

1 to 10 of 29

See all 29 papers

Grants0

The grants NIH RePORTER links to the trial, newest funded first: NIH's, and some of AHRQ's, CDC's, FDA's and VA's. Each shows its title, principal investigators, organization and funder in its newest year.

None in this release.

Trial comparisons0

Comparisons of the trial's two groups, calculated by ConductScience from the counts it posted.

None in this release.

Tests0

The ConductCognition tests this trial's registered outcomes name, as ScienceGraph matched them in trial-tests-2026-11-12-0.2.1.

None in this release.

Data dates

The day each source was copied for this release.

ClinicalTrials.gov
2026-11-12
ClinicalTrials.gov
Results, from AACT
2026-03-23
AACT
NIH grant links
2026-11-13
NIH RePORTER

Sources 3

  • ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
  • ClinicalTrials.govNo license stated
  • NIH RePORTER's clinical studies and project filesPublic domain
Each source's terms
  • ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
  • ClinicalTrials.govnone stated
  • NIH RePORTER's clinical studies and project filesPublic domain (NIH RePORTER)

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

For software

Read this trial from software.

The record and each of its lists are JSON, twenty rows a page. No key.

GET https://conductscience.org/api/trials/v1/NCT02307500

GET https://conductscience.org/api/trials/v1/NCT02307500/papers?page=2