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Trial · NCT02307682

Results by group1,112

Each measurement the trial posted, group by group, in the words and numbers it posted.

OutcomeGroupCategoryValueSpreadUnits
Change From Baseline in Best Corrected Visual Acuity (BCVA) (Letters Read) at Week 48 - Study EyeBrolucizumab 3 mg5.9Standard Deviation 13.49letters
Change From Baseline in Best Corrected Visual Acuity (BCVA) (Letters Read) at Week 48 - Study EyeBrolucizumab 6 mg6.4Standard Deviation 14.40letters
Change From Baseline in Best Corrected Visual Acuity (BCVA) (Letters Read) at Week 48 - Study EyeAflibercept 2 mg7.0Standard Deviation 13.16letters
Average Change From Baseline in BCVA (Letters Read) Over the Period Week 36 Through Week 48 - Study EyeBrolucizumab 3 mg6.0Standard Deviation 13.37letters
Average Change From Baseline in BCVA (Letters Read) Over the Period Week 36 Through Week 48 - Study EyeBrolucizumab 6 mg6.5Standard Deviation 13.85letters
Average Change From Baseline in BCVA (Letters Read) Over the Period Week 36 Through Week 48 - Study EyeAflibercept 2 mg6.9Standard Deviation 12.61letters
Proportion of Subjects With Positive q12 (Every 12 Weeks) Treatment Status at Week 48Brolucizumab 3 mg0.493995% Confidence Interval 0.4393 to 0.5461proportion of subjects
Proportion of Subjects With Positive q12 (Every 12 Weeks) Treatment Status at Week 48Brolucizumab 6 mg0.556395% Confidence Interval 0.5016 to 0.6075proportion of subjects
Proportion of Subjects With Positive q12 Treatment Status at Week 48 Within the Subjects With no q8 (Every 8 Weeks) Treatment Need During the First q12 Cycle (Week 16, Week 20)Brolucizumab 3 mg0.808595% Confidence Interval 0.7454 to 0.8574proportion of subjects
Proportion of Subjects With Positive q12 Treatment Status at Week 48 Within the Subjects With no q8 (Every 8 Weeks) Treatment Need During the First q12 Cycle (Week 16, Week 20)Brolucizumab 6 mg0.853995% Confidence Interval 0.7987 to 0.8950proportion of subjects
Proportion of Subjects With Positive q12 Treatment Status up to Week 96Brolucizumab 3 mg0.397395% Confidence Interval 0.3427 to 0.4514proportion of subjects
Proportion of Subjects With Positive q12 Treatment Status up to Week 96Brolucizumab 6 mg0.453795% Confidence Interval 0.3984 to 0.5072proportion of subjects
Proportion of Subjects With Positive q12 Treatment Status at Week 96 Within the Subjects With no q8 Treatment Need During the Initial q12 Cycle (Week 16, Week 20)Brolucizumab 3 mg0.650495% Confidence Interval 0.5749 to 0.7159proportion of subjects
Proportion of Subjects With Positive q12 Treatment Status at Week 96 Within the Subjects With no q8 Treatment Need During the Initial q12 Cycle (Week 16, Week 20)Brolucizumab 6 mg0.696395% Confidence Interval 0.6270 to 0.7554proportion of subjects
Change From Baseline in BCVA (Letters Read) at Each Post-baseline Visit - Study EyeBrolucizumab 3 mgChange from baseline at Week 43.7Standard Deviation 8.36letters
Change From Baseline in BCVA (Letters Read) at Each Post-baseline Visit - Study EyeBrolucizumab 6 mgChange from baseline at Week 43.8Standard Deviation 9.77letters
Change From Baseline in BCVA (Letters Read) at Each Post-baseline Visit - Study EyeAflibercept 2 mgChange from baseline at Week 44.2Standard Deviation 7.93letters
Change From Baseline in BCVA (Letters Read) at Each Post-baseline Visit - Study EyeBrolucizumab 3 mgChange from baseline at Week 85.7Standard Deviation 8.83letters
Change From Baseline in BCVA (Letters Read) at Each Post-baseline Visit - Study EyeBrolucizumab 6 mgChange from baseline at Week 85.5Standard Deviation 10.71letters
Change From Baseline in BCVA (Letters Read) at Each Post-baseline Visit - Study EyeAflibercept 2 mgChange from baseline at Week 86.1Standard Deviation 9.48letters

Source ClinicalTrials.govtrials-2026-11-12-0.5.0

Sources 3

  • ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
  • ClinicalTrials.govNo license stated
  • NIH RePORTER's clinical studies and project filesPublic domain
Each source's terms
  • ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
  • ClinicalTrials.govnone stated
  • NIH RePORTER's clinical studies and project filesPublic domain (NIH RePORTER)

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

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