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Trial · NCT02322892

Registered outcomes11

Each outcome the trial registered, primary first, in ClinicalTrials.gov's words.

ListOutcomeTime frameDescription
PrimaryLactate LevelsPost-surgery within 1 hour of arrival to the ICU
SecondaryPercentage Change From Baseline in Pyruvate Dehydrogenase (PDH) Enzyme ActivityPost-surgery within 1 hour of arrival to the ICUPDH activity will be measured in isolated peripheral blood mononuclear cells using a novel immunocapture and microplate-based method. Reported as relative change from before the surgery.
SecondaryPatients With Post-operative ComplicationsUntil hospital discharge, limit 60 daysAtrial fibrillation, delirium, renal failure, stroke, myocardial infarction, acute respiratory distress syndrome, infection
SecondaryLength of StayUntil hospital discharge, limit 60 daysDuration of intensive care unit stay
SecondaryMortalityUntil hospital discharge, limit 60 days
OtherLactate LevelsSix hours after end of surgery surgery
OtherPyruvate Dehydrogenase (PDH) Enzyme ActivitySix hours after end of surgery surgeryPDH activity will be measured in isolated peripheral blood mononuclear cells using a novel immunocapture and microplate-based method
OtherTime on Mechanical VentilationLimit 60 days
OtherTime on VasopressorsLimit 60 days
OtherGlobal Oxygen Consumption (VO2)From arrival to ICU to extubation, limit 6 hoursVO2 will be measured with a Compact Anesthesia monitor
OtherCellular Oxygen ConsumptionPost-surgery within 1 hour of arrival to the ICUCellular (peripheral blood mononuclear cells) oxygen consumption measured with the XFe24 Extracellular Flux Analyzers

Source ClinicalTrials.govtrials-2026-11-12-0.5.0

Sources 3

  • ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
  • ClinicalTrials.govNo license stated
  • NIH RePORTER's clinical studies and project filesPublic domain
Each source's terms
  • ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
  • ClinicalTrials.govnone stated
  • NIH RePORTER's clinical studies and project filesPublic domain (NIH RePORTER)

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

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