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Trial · NCT02325713

Results by group243

Each measurement the trial posted, group by group, in the words and numbers it posted.

OutcomeGroupCategoryValueSpreadUnits
Area Under the Plasma Concentration-time Curve (AUC) From Time Zero to Infinity (AUC0-inf) Adjusted for the Actual Administered Dose (AUC0-inf, Adj) of L-Praziquantel (L-PZQ)Treatment A: 40 mg/kg Test ODT-PZQ After Meal1969.6Geometric Coefficient of Variation 47.2Hour*nanograms per milliliter (h*ng/mL)
Area Under the Plasma Concentration-time Curve (AUC) From Time Zero to Infinity (AUC0-inf) Adjusted for the Actual Administered Dose (AUC0-inf, Adj) of L-Praziquantel (L-PZQ)Treatment B: 40 mg/kg Cysticide Tablet After Meal2047.9Geometric Coefficient of Variation 60.2Hour*nanograms per milliliter (h*ng/mL)
Area Under the Plasma Concentration-time Curve (AUC) From Time Zero to Infinity (AUC0-inf) Adjusted for the Actual Administered Dose (AUC0-inf, Adj) of L-Praziquantel (L-PZQ)Treatment C1: 20 mg/kg Test ODT-PZQ After Meal345.4Geometric Coefficient of Variation 69.5Hour*nanograms per milliliter (h*ng/mL)
Area Under the Plasma Concentration-time Curve (AUC) From Time Zero to Infinity (AUC0-inf) Adjusted for the Actual Administered Dose (AUC0-inf, Adj) of L-Praziquantel (L-PZQ)Treatment C2: 60 mg/kg Test ODT-PZQ After Meal4871.3Geometric Coefficient of Variation 42.2Hour*nanograms per milliliter (h*ng/mL)
Area Under the Plasma Concentration-time Curve (AUC) From Time Zero to Infinity (AUC0-inf) Adjusted for the Actual Administered Dose (AUC0-inf, Adj) of L-Praziquantel (L-PZQ)Treatment D1: 40 mg/kg Test ODT-PZQ Without Meal924.9Geometric Coefficient of Variation 67.7Hour*nanograms per milliliter (h*ng/mL)
Area Under the Plasma Concentration-time Curve (AUC) From Time Zero to Infinity (AUC0-inf) Adjusted for the Actual Administered Dose (AUC0-inf, Adj) of L-Praziquantel (L-PZQ)Treatment D2: 40 mg/kg Cysticide Crushed Tablets After Meal1537.7Geometric Coefficient of Variation 70.6Hour*nanograms per milliliter (h*ng/mL)
Maximum Observed Concentration in Plasma (Cmax) Adjusted for the Actual Administered Dose (Cmax, Adj) of L-PZQ, D-PZQ and Racemate PZQTreatment A: 40 mg/kg Test ODT-PZQ After MealL-PZQ881.3Geometric Coefficient of Variation 57.2ng/mL
Maximum Observed Concentration in Plasma (Cmax) Adjusted for the Actual Administered Dose (Cmax, Adj) of L-PZQ, D-PZQ and Racemate PZQTreatment B: 40 mg/kg Cysticide Tablet After MealL-PZQ762.6Geometric Coefficient of Variation 59.5ng/mL
Maximum Observed Concentration in Plasma (Cmax) Adjusted for the Actual Administered Dose (Cmax, Adj) of L-PZQ, D-PZQ and Racemate PZQTreatment C1: 20 mg/kg Test ODT-PZQ After MealL-PZQ154.6Geometric Coefficient of Variation 80.4ng/mL
Maximum Observed Concentration in Plasma (Cmax) Adjusted for the Actual Administered Dose (Cmax, Adj) of L-PZQ, D-PZQ and Racemate PZQTreatment C2: 60 mg/kg Test ODT-PZQ After MealL-PZQ1548Geometric Coefficient of Variation 32.6ng/mL
Maximum Observed Concentration in Plasma (Cmax) Adjusted for the Actual Administered Dose (Cmax, Adj) of L-PZQ, D-PZQ and Racemate PZQTreatment D1: 40 mg/kg Test ODT-PZQ Without MealL-PZQ189.3Geometric Coefficient of Variation 104.0ng/mL
Maximum Observed Concentration in Plasma (Cmax) Adjusted for the Actual Administered Dose (Cmax, Adj) of L-PZQ, D-PZQ and Racemate PZQTreatment D2: 40 mg/kg Cysticide Crushed Tablets After MealL-PZQ446.3Geometric Coefficient of Variation 87.6ng/mL
Maximum Observed Concentration in Plasma (Cmax) Adjusted for the Actual Administered Dose (Cmax, Adj) of L-PZQ, D-PZQ and Racemate PZQTreatment A: 40 mg/kg Test ODT-PZQ After MealD-PZQ2330Geometric Coefficient of Variation 30.7ng/mL
Maximum Observed Concentration in Plasma (Cmax) Adjusted for the Actual Administered Dose (Cmax, Adj) of L-PZQ, D-PZQ and Racemate PZQTreatment B: 40 mg/kg Cysticide Tablet After MealD-PZQ2179Geometric Coefficient of Variation 33.0ng/mL
Maximum Observed Concentration in Plasma (Cmax) Adjusted for the Actual Administered Dose (Cmax, Adj) of L-PZQ, D-PZQ and Racemate PZQTreatment C1: 20 mg/kg Test ODT-PZQ After MealD-PZQ786.3Geometric Coefficient of Variation 41.5ng/mL
Maximum Observed Concentration in Plasma (Cmax) Adjusted for the Actual Administered Dose (Cmax, Adj) of L-PZQ, D-PZQ and Racemate PZQTreatment C2: 60 mg/kg Test ODT-PZQ After MealD-PZQ3234Geometric Coefficient of Variation 20.0ng/mL
Maximum Observed Concentration in Plasma (Cmax) Adjusted for the Actual Administered Dose (Cmax, Adj) of L-PZQ, D-PZQ and Racemate PZQTreatment D1: 40 mg/kg Test ODT-PZQ Without MealD-PZQ838.5Geometric Coefficient of Variation 65.7ng/mL
Maximum Observed Concentration in Plasma (Cmax) Adjusted for the Actual Administered Dose (Cmax, Adj) of L-PZQ, D-PZQ and Racemate PZQTreatment D2: 40 mg/kg Cysticide Crushed Tablets After MealD-PZQ1556Geometric Coefficient of Variation 35.8ng/mL
Maximum Observed Concentration in Plasma (Cmax) Adjusted for the Actual Administered Dose (Cmax, Adj) of L-PZQ, D-PZQ and Racemate PZQTreatment A: 40 mg/kg Test ODT-PZQ After MealRacemate PZQ3250Geometric Coefficient of Variation 34.6ng/mL
Maximum Observed Concentration in Plasma (Cmax) Adjusted for the Actual Administered Dose (Cmax, Adj) of L-PZQ, D-PZQ and Racemate PZQTreatment B: 40 mg/kg Cysticide Tablet After MealRacemate PZQ2974Geometric Coefficient of Variation 37.2ng/mL

Source ClinicalTrials.govtrials-2026-11-12-0.5.0

Sources 3

  • ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
  • ClinicalTrials.govNo license stated
  • NIH RePORTER's clinical studies and project filesPublic domain
Each source's terms
  • ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
  • ClinicalTrials.govnone stated
  • NIH RePORTER's clinical studies and project filesPublic domain (NIH RePORTER)

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

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