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Trial · NCT02334306

Results by group26

Each measurement the trial posted, group by group, in the words and numbers it posted.

OutcomeGroupCategoryValueSpreadUnits
Change From Baseline in European League Against Rheumatism Sjogren's Syndrome Disease Activity Index (ESSDAI) Score at Day 99Placebo-2.3Standard Error 0.8Scores on a scale
Change From Baseline in European League Against Rheumatism Sjogren's Syndrome Disease Activity Index (ESSDAI) Score at Day 99MEDI5872 210 mg-3.8Standard Error 0.9Scores on a scale
Ratio to Baseline in Peripheral Blood Biomarkers at Day 99PlaceboPlasma Cell Levels0.70Standard Error 0.24Ratio
Ratio to Baseline in Peripheral Blood Biomarkers at Day 99MEDI5872 210 mgPlasma Cell Levels0.65Standard Error 0.24Ratio
Ratio to Baseline in Peripheral Blood Biomarkers at Day 99PlaceboTFH Cells0.94Standard Error 0.27Ratio
Ratio to Baseline in Peripheral Blood Biomarkers at Day 99MEDI5872 210 mgTFH Cells0.62Standard Error 0.27Ratio
Ratio to Baseline in Minor Salivary Gland Tissue Biomarkers at Day 99PlaceboTotal Plasma Cells1.32Standard Error 0.13Ratio
Ratio to Baseline in Minor Salivary Gland Tissue Biomarkers at Day 99MEDI5872 210 mgTotal Plasma Cells1.15Standard Error 0.11Ratio
Ratio to Baseline in Minor Salivary Gland Tissue Biomarkers at Day 99PlaceboCD4/ICOS TFH Cells1.76Standard Error 0.21Ratio
Ratio to Baseline in Minor Salivary Gland Tissue Biomarkers at Day 99MEDI5872 210 mgCD4/ICOS TFH Cells0.75Standard Error 0.18Ratio
Ratio to Baseline in Minor Salivary Gland Tissue Biomarkers at Day 99PlaceboPD-1/ICOS TFH Cells1.06Standard Error 0.19Ratio
Ratio to Baseline in Minor Salivary Gland Tissue Biomarkers at Day 99MEDI5872 210 mgPD-1/ICOS TFH Cells1.07Standard Error 0.16Ratio
Ratio to Baseline in Focus Score at Day 99Placebo0.79Standard Deviation 0.53Ratio
Ratio to Baseline in Focus Score at Day 99MEDI5872 210 mg0.96Standard Deviation 0.50Ratio
Change From Baseline in European League Against Rheumatism Sjogren's Syndrome Patient Reported Index (ESSPRI) Score at Day 99Placebo-1.0Standard Error 0.5Scores on a scale
Change From Baseline in European League Against Rheumatism Sjogren's Syndrome Patient Reported Index (ESSPRI) Score at Day 99MEDI5872 210 mg-0.6Standard Error 0.5Scores on a scale
Percentage of ESSDAI Responders at Day 99PlaceboESSDAI [3]18.8Percentage of participants
Percentage of ESSDAI Responders at Day 99MEDI5872 210 mgESSDAI [3]43.8Percentage of participants
Percentage of ESSDAI Responders at Day 99PlaceboESSDAI [4]18.8Percentage of participants
Percentage of ESSDAI Responders at Day 99MEDI5872 210 mgESSDAI [4]43.8Percentage of participants

Source ClinicalTrials.govtrials-2026-11-12-0.5.0

Sources 3

  • ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
  • ClinicalTrials.govNo license stated
  • NIH RePORTER's clinical studies and project filesPublic domain
Each source's terms
  • ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
  • ClinicalTrials.govnone stated
  • NIH RePORTER's clinical studies and project filesPublic domain (NIH RePORTER)

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

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GET https://conductscience.org/api/trials/v1/NCT02334306/results