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Trial · NCT02339740

Outcomes13

Each outcome the trial posted results for, in ClinicalTrials.gov's words.

TypeOutcomeTime framePopulationUnitsMeasured as
PRIMARYEvent-free Survival (EFS) in Standard Risk Acute Promyelocytic Leukemia (APL) PatientsUp to 24 monthsPatients ineligible, did not start treatment, or RQPCR positive not confirmed are excluded from analyses of EFSpercentage of participantsNUMBER
PRIMARYEFS in High Risk APL PatientsUp to 24 monthsPatients ineligible, did not start treatment, or RQPCR positive not confirmed are excluded from analyses of EFSpercentage of participantsNUMBER
OTHER_PRE_SPECIFIEDInduction Death Rate for Patients With FLT3 Mutations and Wild Type FLT3Up to 70 days
OTHER_PRE_SPECIFIEDDisease Free Survival (DFS)Up to 70 days
OTHER_PRE_SPECIFIEDIncidence of Serious Early Coagulopathy Events, Defined as Grade 3 or Higher Hemorrhage or ThrombosisUp to 29 days of induction therapy
OTHER_PRE_SPECIFIEDChange in CogState Scores, Defined as a Decline of 5 Units in Mean Scores Apparent at 2 Years Off TherapyEnd of induction up to 2 years post-treatment
OTHER_PRE_SPECIFIEDChange in Parent-reported Executive Functioning Over Time, Defined as a Decline of 5 Units in Mean Scores Apparent at 2 Years Off TherapyEnd of induction up to 2 years post-treatment
OTHER_PRE_SPECIFIEDChange in Intellectual Functioning, Defined by Declines on the Wechsler-derived Estimated Intelligence Quotient and Processing Speed ScoresEnd of treatment to 4 years post-treatment
OTHER_PRE_SPECIFIEDChange in Memory Functioning, Defined by Declines on the Children's Memory Scale Faces and Stories Memory ScoresEnd of treatment to 4 years post-treatment
OTHER_PRE_SPECIFIEDChange in Verbal Learning Functioning, Defined by Declines on the California Verbal Learning Test Total ScoreEnd of treatment to 4 years post-treatment
OTHER_PRE_SPECIFIEDChange in Adaptive Functioning, Defined by Declines on the Adaptive Behavior Assessment System-II General Adaptive Behavior Composite ScoreEnd of treatment to 4 years post-treatment
OTHER_PRE_SPECIFIEDChange in Parent-reported Psychosocial Functioning Over TimeEnd of treatment to 4 years off-therapy
OTHER_PRE_SPECIFIEDChange in Parent-reported Quality of Life (QOL) Over TimeEnd of treatment to 4 years

Source ClinicalTrials.govtrials-2026-11-12-0.4.0

Sources 3

  • ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
  • ClinicalTrials.govNo license stated
  • NIH RePORTER's clinical studies and project filesPublic domain
Each source's terms
  • ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
  • ClinicalTrials.govnone stated
  • NIH RePORTER's clinical studies and project filesPublic domain (NIH RePORTER)

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

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