The Effect of Calcifediol (Hy.D 25 SD/S) and Vitamin D3 on Muscle Strength in a Frail Elderly Population
NCT02349282, Not applicable, Completed, Wageningen University
Trial 10
As registered on ClinicalTrials.gov, in the graph's capture of the registry.
| Field | Value | Source |
|---|---|---|
| Title | The Effect of Calcifediol (Hy.D 25 SD/S) and Vitamin D3 on Muscle Strength in a Frail Elderly Population | ClinicalTrials.gov |
| NCT number | NCT02349282 | ClinicalTrials.gov |
| Status | Completed | ClinicalTrials.gov |
| Phases | Not applicable | ClinicalTrials.gov |
| Enrollment | 78 participants, actual | ClinicalTrials.gov |
| Lead sponsor | Wageningen University | ClinicalTrials.gov |
| Conditions | Deficiency, Vitamin D, Elderly, Frail | ClinicalTrials.gov |
| Interventions | Calcifediol 10ug/day, Vitamin D3 20ug/day, Placebo | ClinicalTrials.gov |
| First posted | 2015-01-28 | ClinicalTrials.gov |
| Last updated | 2016-01-11 | ClinicalTrials.gov |
Registered outcomes 16
Each outcome the trial registered, primary first, in ClinicalTrials.gov's words.
| List | Outcome | Time frame | Description | Source |
|---|---|---|---|---|
| Primary | Change in muscle strength, knee extension strength (measured by Biodex System) | baseline, week 12, end of study (after 24 weeks supplementation) | measured by Biodex System | ClinicalTrials.gov |
| Secondary | Change in knee flexion strength (measured by Biodex System) | baseline, week 12, end of study (after 24 weeks supplementation) | measured by Biodex System | ClinicalTrials.gov |
| Secondary | Change in handgrip strength | baseline, week 12, end of study (after 24 weeks supplementation) | ClinicalTrials.gov | |
| Secondary | Change in SPPB | baseline, week 12, end of study (after 24 weeks supplementation) | ClinicalTrials.gov | |
| Secondary | Change in Timed Up and Go test | baseline, week 12, end of study (after 24 weeks supplementation) | ClinicalTrials.gov | |
| Secondary | Change in Postural Body Sway | baseline, week 12, end of study (after 24 weeks supplementation) | ClinicalTrials.gov | |
| Secondary | Change in serum Vitamin D3 | baseline, week 12, end of study (after 24 weeks supplementation) | ClinicalTrials.gov | |
| Secondary | Change in serum 25(OH)D | baseline, week 12, end of study (after 24 weeks supplementation) | ClinicalTrials.gov | |
| Secondary | Change in serum 1,25(OH)2D3 | baseline, week 12, end of study (after 24 weeks supplementation) | ClinicalTrials.gov | |
| Secondary | Change in serum 24,25(OH)2D | baseline, week 12, end of study (after 24 weeks supplementation) | ClinicalTrials.gov | |
| Secondary | Frequency of falling | baseline, week 12, end of study (after 24 weeks supplementation) | ClinicalTrials.gov | |
| Secondary | Change in muscle fibre type and size (Biopsy) | baseline, end of study (after 24 weeks supplementation) | Biopsy | ClinicalTrials.gov |
| Secondary | Change in body composition (DEXA-scan) | baseline, end of study (after 24 weeks supplementation) | DEXA-scan | ClinicalTrials.gov |
| Secondary | Change in cognitive functioning (Trail making, Stroop-test, Letter fluency) | baseline, end of study (after 24 weeks supplementation) | Trail making, Stroop-test, Letter fluency | ClinicalTrials.gov |
| Secondary | Change in vital Signs (blood pressure and heart rate) | baseline, week 12, end of study (after 24 weeks supplementation) | blood pressure and heart rate | ClinicalTrials.gov |
| Secondary | Change in neuromuscular measurements (MUNIX, MUSIX by EMG) | baseline, end of study (after 24 weeks supplementation) | MUNIX, MUSIX by EMG | ClinicalTrials.gov |
Outcomes 0
Each outcome the trial posted results for, in ClinicalTrials.gov's words.
| Type | Outcome | Time frame | Population | Units | Measured as | Source |
|---|
Results by group 0
Each measurement the trial posted, group by group, in the words and numbers it posted.
| Outcome | Group | Category | Value | Spread | Units | Source |
|---|
Participant flow 0
How many started, completed or left each group, period by period.
| Period | Milestone | Group | Participants | Units counted | Source |
|---|
Adverse events 0
Each adverse event the trial posted, group by group: the participants affected out of those at risk.
| Type | Event | Organ system | Group | Affected | At risk | Events | Source |
|---|
Adverse event totals 0
The totals the trial posted for each group.
| Total | Group | Affected | At risk | Source |
|---|
Papers 2
The papers the trial lists on ClinicalTrials.gov.
Grants 0
The grants NIH RePORTER links to the trial, newest funded first: NIH's, and some of AHRQ's, CDC's, FDA's and VA's. Each shows its title, principal investigators, organization and funder in its newest year.
| Project | Title | Principal investigators | Organization | Funder | Fiscal years | Source |
|---|
Trial comparisons 0
Comparisons of the trial's two groups, calculated by ConductScience from the counts it posted.
| Comparison | Source |
|---|
Tests 4
The ConductCognition tests this trial's registered outcomes name, as ScienceGraph matched them in trial-tests-2026-11-12-0.2.1.
| Test | Named as | Source |
|---|---|---|
| Stroop Color-Word Test | Secondary outcome | ConductCognition |
| Trail Making Test A | Secondary outcome | ConductCognition |
| Trail Making Test B | Secondary outcome | ConductCognition |
| Verbal Fluency | Secondary outcome | ConductCognition |
Source 5
| Field | Value | Source |
|---|---|---|
| Release | trials-2026-11-12-0.4.0 | ClinicalTrials.gov |
| Release manifest SHA-256 | 0f4a8d8c48aee2a7573ae0fa94ecbeab70c1adbe449bbc95c424bc7d3e97b9d4 | ClinicalTrials.gov |
| Registry capture | 2026-11-12 | ClinicalTrials.gov |
| Results copy, AACT | 2026-03-23 | ClinicalTrials.gov |
| NIH clinical studies file | 2026-11-13 | ClinicalTrials.gov |
Release trials-2026-11-12-0.4.0
ClinicalTrials.gov's posted results, through CTTI's AACT: ClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299 ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.
ClinicalTrials.gov: none stated ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.
NIH RePORTER's clinical studies and project files: Public domain (NIH RePORTER)