Trial · NCT02352896
Registered outcomes12
Each outcome the trial registered, primary first, in ClinicalTrials.gov's words.
1 to 12 of 12
Download this page as JSON| List | Outcome | Time frame | Description |
|---|---|---|---|
| Primary | Disease Severity as Measured by Newcastle Pediatric Mitochondrial Disease Scale (NPMDS) Sections 1-3 Score | Baseline up to Month 36 | NPMDS is a validated scale to assess the mitochondrial disease progression. |
| Primary | Number of Participants With Dose-Limiting Serious Adverse Events (SAEs) | Baseline up to Month 36 | |
| Secondary | Bayley Scales of Infant Development-III Score (Participants Age 0-3) | Baseline up to Month 24 | Effect of EPI-743 on neurodevelopment will be measured by Bayley Scales of Infant Development-III score. |
| Secondary | Wechsler Scale of Intelligence and Movement Assessment Battery Score for Children (Participants Age 4-18) | Baseline up to Month 24 | Effect of EPI-743 on neuromuscular function will be assessed by Wechsler Scale of Intelligence and Movement Assessment Battery score. |
| Secondary | Barry-Albright Dystonia Scale Score | Baseline up to Month 24 | Neuromuscular function will be assessed by Barry-Albright Dystonia Scale score. |
| Secondary | Gross Motor Function Measure | Baseline up to Month 24 | Neuromuscular function will be assessed by gross motor function measure. |
| Secondary | Awake Oxygen Saturation Levels | Baseline up to Month 24 | Effect of EPI-743 on respiratory function will be measured by awake oxygen saturation levels. |
| Secondary | Total Ventilator Days and Total Intensive Care Unit Days | Baseline up to Month 24 | |
| Secondary | Number of Participants With Pneumonia Episodes and Tracheostomy | Baseline up to Month 24 | |
| Secondary | Total Number of Mortalities, Medical Encounters, Hospitalizations, and Hospital Days | Baseline up to Month 24 | |
| Secondary | Health-Related Quality of Life as Measured by NPMDS Section 4 Score | Baseline up to Month 24 | |
| Secondary | Glutathione Cycle Biomarkers Level | Baseline up to Month 24 |
Source ClinicalTrials.govtrials-2026-11-12-0.5.0
Sources 3
- ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
- ClinicalTrials.govNo license stated
- NIH RePORTER's clinical studies and project filesPublic domain
Each source's terms
- ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
- ClinicalTrials.govnone stated
- NIH RePORTER's clinical studies and project filesPublic domain (NIH RePORTER)
ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.
For software
Read this list from software.
Twenty rows a page, as JSON. No key.
GET https://conductscience.org/api/trials/v1/NCT02352896/registered