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Trial · NCT02363452

Reverse Transcriptase Inhibitors in AGS

NCT02363452, Phase 2, Completed, Assistance Publique - Hôpitaux de Paris

3 sourcestrials-2026-11-12-0.5.0

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ConductScience Library. Reverse Transcriptase Inhibitors in AGS. Trials, record NCT02363452. Release trials-2026-11-12-0.5.0, 12 Nov 2026. https://conductscience.org/library/trials/NCT02363452

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Trial

As registered on ClinicalTrials.gov, in the graph's capture of the registry.

Title
Reverse Transcriptase Inhibitors in AGS
NCT number
NCT02363452
Status
Completed
Phases
Phase 2
Enrollment
11 participants, actual
Lead sponsor
Assistance Publique - Hôpitaux de Paris
Conditions
Aicardi-Goutières Syndrome (AGS)
Interventions
Reverse transcriptase inhibitors: Zidovudine, Lamivudine, Abacavir
First posted
2015-02-16
Last updated
2025-09-05

Source ClinicalTrials.gov

Registered outcomes30

Each outcome the trial registered, primary first, in ClinicalTrials.gov's words.

ListOutcomeTime frameDescription
PrimaryInterferon signatureBefore and after 12 months of treatmentInterferon Score
SecondaryInterferon signatureMonth 18Interferon Score
SecondaryAdverse EventsBaseline until Month 18
SecondaryInterferon Activity Level in cerebrospinal fluid (UI/L)Within the 12 month on treatment
SecondaryInterferon Activity Level in blood (UI/L)Within the 12 month on treatment
SecondaryInterferon Activity Level in blood (UI/L)month 18
SecondaryInterferon Protein in cerebrospinal fluid (Fg/mL)within the 12 month on treatment
SecondaryInterferon Protein in blood (FG/mL)Within the 12 month on treatment
SecondaryInterferon Protein in blood (Fg/mL)Month 18
SecondaryNeurological assessmentBaselineScale for Evaluation of Movement Disorders Vineland Adaptive Behaviour Scales

Outcomes0

Each outcome the trial posted results for, in ClinicalTrials.gov's words.

None in this release.

Results by group0

Each measurement the trial posted, group by group, in the words and numbers it posted.

None in this release.

Participant flow0

How many started, completed or left each group, period by period.

None in this release.

Adverse events0

Each adverse event the trial posted, group by group: the participants affected out of those at risk.

None in this release.

Adverse event totals0

The totals the trial posted for each group.

None in this release.

Papers2

The papers the trial lists on ClinicalTrials.gov.

PMIDListed asSource
23607857BACKGROUNDPubMed
30566312RESULTPubMed

Grants0

The grants NIH RePORTER links to the trial, newest funded first: NIH's, and some of AHRQ's, CDC's, FDA's and VA's. Each shows its title, principal investigators, organization and funder in its newest year.

None in this release.

Trial comparisons0

Comparisons of the trial's two groups, calculated by ConductScience from the counts it posted.

None in this release.

Tests0

The ConductCognition tests this trial's registered outcomes name, as ScienceGraph matched them in trial-tests-2026-11-12-0.2.1.

None in this release.

Data dates

The day each source was copied for this release.

ClinicalTrials.gov
2026-11-12
ClinicalTrials.gov
Results, from AACT
2026-03-23
AACT
NIH grant links
2026-11-13
NIH RePORTER

Sources 3

  • ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
  • ClinicalTrials.govNo license stated
  • NIH RePORTER's clinical studies and project filesPublic domain
Each source's terms
  • ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
  • ClinicalTrials.govnone stated
  • NIH RePORTER's clinical studies and project filesPublic domain (NIH RePORTER)

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

For software

Read this trial from software.

The record and each of its lists are JSON, twenty rows a page. No key.

GET https://conductscience.org/api/trials/v1/NCT02363452

GET https://conductscience.org/api/trials/v1/NCT02363452/registered?page=2